EFFECT OF WHOLE BODY X-IRRADIATION ON INDUCTION OF ALLERGIC ENCEPHALOMYELITIS IN RATS.

Allergic encephalomyelitis (AE) is suppressed in rats given whole body x-irradiation prior to sensitization with spinal cord plus adjuvant. Suppression of the disease is paralleled by reduced production of complement-fixing antibrain antibodies. There is little, if any, suppression of delayed-type immunologic reactivity, based on tuberculin skin testing. X-irradiation after sensitization does not suppress AE. The meaning of these findings with respect to pathogenesis of AE is discussed.

• Publication year

  1963

• Venue

  Journal of Immunology

• Publication date

  1963-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.90.4.532PMID 14082015
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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