Embedding embryos for high-resolution episcopic microscopy (HREM).

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Cold Spring Harbor Protocols

• Publication date

  2012-06-01

• Fields of study

  Biology, Medicine, Materials Science

• Identifiers
  DOI 10.1101/pdb.prot069583PMID 22661437
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Episcopic three-dimensional imaging of embryos.

  2012cited by this paper
• Embedding embryos for episcopic fluorescence image capturing (EFIC).

  2012cited by this paper
• Generation of volume data by episcopic three-dimensional imaging of embryos.

  2012cited by this paper

• Programming of pluripotency and the germ line co-evolved from a Nanog ancestor.

  2025cites this paper
• E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development

  2025cites this paper
• Dermal Arteries of the Human Thumb: Arterial Units, Sucquet-Hoyer Canals, and Arterio-Arterial Anastomoses in Pad Versus Tip.

  2025cites this paper
• 4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.

  2024cites this paper
• Genetic determinants of micronucleus formation in vivo

  2024cites this paper
• In search of the glow—Three‐dimensional reconstruction of Latia neritoides with specific focus on the mantel cavity (Mollusca; Gastropoda; Hygrophila)

  2024cites this paper
• Three-dimensional structural and metric characterisation of cardioids

  2024cites this paper
• Cardiac development demystified by use of the HDBR atlas

  2024cites this paper
• Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease

  2023cites this paper
• Effects of Tulp4 deficiency on murine embryonic development and adult phenotype

  2023cites this paper
• Development of the arterial roots and ventricular outflow tracts

  2023cites this paper
• Revisiting the anatomy of the right ventricle in the light of knowledge of its development

  2023cites this paper
• An end-to-end pipeline based on open source deep learning tools for reliable analysis of complex 3D images of ovaries.

  2023cites this paper
• Hypochondroplasia gain-of-function mutation in FGFR3 causes defective bone mineralization in mice

  2023cites this paper
• NANOG is required to establish the competence for germ-layer differentiation in the basal tetrapod axolotl

  2023cites this paper
• Timeline of Developmental Defects Generated upon Genetic Inhibition of the Retinoic Acid Receptor Signaling Pathway

  2023cites this paper
• PKN2 deficiency leads both to prenatal ‘congenital’ cardiomyopathy and defective angiotensin II stress responses

  2022cites this paper
• Combined method of whole mount and block‐face imaging: Acquisition of 3D data of gene expression pattern from conventional in situ hybridization

  2022cites this paper
• Detailed quantification of cardiac ventricular myocardial architecture in the embryonic and fetal mouse heart by application of structure tensor analysis to high resolution episcopic microscopic data

  2022cites this paper
• Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants

  2022cites this paper
• Visualizing 3D Embryo and Tissue Morphology—A Decade of Using High-Resolution Episcopic Microscopy (HREM) in Biomedical Imaging

  2022cites this paper
• Artefacts in Volume Data Generated with High Resolution Episcopic Microscopy (HREM)

  2021cites this paper
• Multimodality imaging beyond CLEM: Showcases of combined in-vivo preclinical imaging and ex-vivo microscopy to detect murine mural vascular lesions.

  2021cites this paper
• Hypoglossal Nerve Abnormalities as Biomarkers for Central Nervous System Defects in Mouse Lines Producing Embryonically Lethal Offspring

  2021cites this paper
• Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant

  2021cites this paper
• SMCHD1 has separable roles in chromatin architecture and gene silencing that could be targeted in disease

  2021cites this paper
• Smooth Muscle Specific Ablation of CXCL12 in Mice Downregulates CXCR7 Associated with Defective Coronary Arteries and Cardiac Hypertrophy

  2021cites this paper
• Cross-Modality Imaging of Murine Tumor Vasculature—a Feasibility Study

  2021cites this paper
• Pathogenesis of Anorectal Malformations in Retinoic Acid Receptor Knockout Mice Studied by HREM

  2021cites this paper
• High Resolution Episcopic Microscopy for Qualitative and Quantitative Data in Phenotyping Altered Embryos and Adult Mice Using the New “Histo3D” System

  2021cites this paper
• The venous system of E14.5 mouse embryos—reference data and examples for diagnosing malformations in embryos with gene deletions

  2021cites this paper
• Control of skeletal morphogenesis by the Hippo-YAP/TAZ pathway

  2020cites this paper
• High-Resolution Episcopic Imaging for Visualization of Dermal Arteries and Nerves of the Auricular Cymba Conchae in Humans

  2020cites this paper
• Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder

  2020cites this paper
• Disruption of embryonic ROCK signaling reproduces the sarcomeric phenotype of hypertrophic cardiomyopathy

  2019cites this paper
• Myoarchitectural disarray of hypertrophic cardiomyopathy begins pre‐birth

  2019cites this paper
• The Col4a2em1(IMPC)Wtsi mouse line: lessons from the Deciphering the Mechanisms of Developmental Disorders program

  2019cites this paper
• Diverse species-specific phenotypic consequences of loss of function sorting nexin 14 mutations

  2019cites this paper
• High-Resolution Episcopic Microscopy (HREM): Looking Back on 13 Years of Successful Generation of Digital Volume Data of Organic Material for 3D Visualisation and 3D Display

  2019cites this paper
• The dermal arteries in the cutaneous angiosome of the descending genicular artery

  2018cites this paper
• High-Resolution Episcopic Microscopy (HREM) using the HistoCore NANOCUT R Rotary Microtome by Leica Biosystems

  2018cites this paper
• Visualising the Cardiovascular System of Embryos of Biomedical Model Organisms with High Resolution Episcopic Microscopy (HREM)

  2018cites this paper
• Quantification of the detailed cardiac left ventricular trabecular morphogenesis in the mouse embryo

  2018cites this paper
• A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)

  2017cites this paper
• Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

  2017cites this paper
• Morphology, topology and dimensions of the heart and arteries of genetically normal and mutant mouse embryos at stages S21–S23

  2017cites this paper
• High-resolution Episcopic Microscopy (HREM) - Simple and Robust Protocols for Processing and Visualizing Organic Materials

  2017cites this paper
• Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution.

  2016cites this paper
• The Informatics of Developmental Phenotypes

  2016cites this paper
• Comparing homologous microscopic sections from multiple embryos using HREM

  2016cites this paper
• The embryological basis of subclinical hypertrophic cardiomyopathy

  2016cites this paper
• 3D modelling and tissue-level morphology of trapeziometacarpal joint

  2016influential citation
• Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

  2016cites this paper
• An Automated Pipeline for Phenotyping Embryonic Lethal Mice using 3D Imaging

  2015cites this paper
• High-Resolution Episcopic Microscopy (HREM): A Tool for Visualizing Skin Biopsies

  2014cites this paper
• Phenotyping structural abnormalities in mouse embryos using high-resolution episcopic microscopy

  2014cites this paper
• The dermal arteries of the human thumb pad

  2013cites this paper
• Episcopic three-dimensional imaging of embryos.

  2012cites this paper
• Generation of volume data by episcopic three-dimensional imaging of embryos.

  2012cites this paper
• Embedding embryos for episcopic fluorescence image capturing (EFIC).

  2012cites this paper