Fanconi anemia: at the Crossroads of DNA repair

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Biochemistry (Moscow)

• Publication date

  2011-02-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1134/S0006297911010068PMID 21568838
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.

  2010cited by this paper
• Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents.

  2010cited by this paper
• Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes.

  2010cited by this paper
• FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

  2010cited by this paper
• The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.

  2010cited by this paper
• Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice.

  2010cited by this paper
• FANCC suppresses short telomere-initiated telomere sister chromatid exchange.

  2010cited by this paper
• Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

  2010cited by this paper
• FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses

  2010cited by this paper
• Ring-shaped Rad51 Paralog Protein Complexes Bind Holliday Junctions and Replication Forks as Visualized by Electron Microscopy*

  2010cited by this paper
• BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair.

  2010cited by this paper
• Stalled replication forks: Making ends meet for recognition and stabilization

  2010cited by this paper
• Promotion and regulation of homologous recombination by DNA helicases.

  2010cited by this paper
• Fanconi anemia and breast cancer susceptibility meet again

  2010cited by this paper
• Rad54, the motor of homologous recombination.

  2010cited by this paper
• A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.

  2010cited by this paper
• The FANCM family of DNA helicases/translocases.

  2010cited by this paper
• ATR activation and replication fork restart are defective in FANCM‐deficient cells

  2010cited by this paper
• DNA repair: A new FAN of the Fanconi anaemia pathway

  2010cited by this paper
• FANCJ: solving problems in DNA replication.

  2010cited by this paper
• A new nuclease member of the FAN club

  2010cited by this paper
• Multiple roles of ERCC1‐XPF in mammalian interstrand crosslink repair

  2010cited by this paper
• FANCJ Uses Its Motor ATPase to Destabilize Protein-DNA Complexes, Unwind Triplexes, and Inhibit RAD51 Strand Exchange*

  2009cited by this paper
• The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51.

  2009cited by this paper
• FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia.

  2009cited by this paper
• FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress.

  2009cited by this paper
• FANCI Binds Branched DNA and Is Monoubiquitinated by UBE2T-FANCL*

  2009cited by this paper
• The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange

  2009cited by this paper
• Structure, function and evolution of the XPD family of iron-sulfur-containing 5'-->3' DNA helicases.

  2009cited by this paper
• Genotype-phenotype correlations in Fanconi anemia.

  2009cited by this paper
• FANCM: A landing pad for the Fanconi Anemia and Bloom's Syndrome complexes.

  2009cited by this paper
• Welcome the Family of FANCJ-like Helicases to the Block of Genome Stability Maintenance Proteins

  2009cited by this paper
• Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.

  2009cited by this paper
• PALB2 links BRCA1 and BRCA2 in the DNA-damage response.

  2009cited by this paper
• How the fanconi anemia pathway guards the genome.

  2009cited by this paper
• FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

  2008cited by this paper
• Homologous recombination and maintenance of genome integrity: cancer and aging through the prism of human RecQ helicases.

  2008cited by this paper
• FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair.

  2008cited by this paper
• Remodeling of DNA replication structures by the branch point translocase FANCM

  2008cited by this paper
• Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24.

  2008cited by this paper
• The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks.

  2008cited by this paper
• The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly.

  2008cited by this paper
• The FANCJ/MutLα interaction is required for correction of the cross‐link response in FA‐J cells

  2007cited by this paper
• Deficiency in incisions produced by XPF at the site of a DNA interstrand cross-link in Fanconi anemia cells.

  2007cited by this paper
• Fanconi anemia is associated with a defect in the BRCA2 partner PALB2

  2007cited by this paper
• Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

  2007cited by this paper
• Interactions between human BRCA2 protein and the meiosis‐specific recombinase DMC1

  2007cited by this paper
• BRCA2: a universal recombinase regulator

  2007cited by this paper
• Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.

  2007cited by this paper
• Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.

  2006cited by this paper
• Mechanism of homologous recombination: mediators and helicases take on regulatory functions

  2006cited by this paper
• DSS1 is required for the stability of BRCA2

  2006cited by this paper
• The DNA repair helicases XPD and FancJ have essential iron-sulfur domains.

  2006cited by this paper
• Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM

  2005cited by this paper
• Fanconi anemia (cross)linked to DNA repair.

  2005cited by this paper
• Analysis of the DNA Substrate Specificity of the Human BACH1 Helicase Associated with Breast Cancer*

  2005cited by this paper
• Direct DNA Binding Activity of the Fanconi Anemia D2 Protein*

  2005cited by this paper
• DNA-bound redox activity of DNA repair glycosylases containing [4Fe-4S] clusters.

  2005cited by this paper
• The RAD51 gene family, genetic instability and cancer.

  2005cited by this paper
• Genetic alterations in accelerated ageing syndromes. Do they play a role in natural ageing?

  2005cited by this paper
• Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells.

  2005cited by this paper
• CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

  2005cited by this paper
• A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

  2005cited by this paper
• The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair.

  2004cited by this paper
• Preferential binding to branched DNA strands and strand-annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex.

  2004cited by this paper
• The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations.

  2004cited by this paper
• PHD domains and E3 ubiquitin ligases: viruses make the connection.

  2003cited by this paper
• Structural insights into BRCA2 function.

  2003cited by this paper
• Fanconi Anemia FANCG Protein in Mitigating Radiation- and Enzyme-Induced DNA Double-Strand Breaks by Homologous Recombination in Vertebrate Cells

  2003cited by this paper
• A novel ubiquitin ligase is deficient in Fanconi anemia

  2003cited by this paper
• FANCE: the link between Fanconi anaemia complex assembly and activity

  2002cited by this paper
• Fork Reversal and ssDNA Accumulation at Stalled Replication Forks Owing to Checkpoint Defects

  2002cited by this paper
• Biallelic Inactivation of BRCA2 in Fanconi Anemia

  2002cited by this paper
• The emerging genetic and molecular basis of Fanconi anaemia

  2001cited by this paper
• BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.

  2001cited by this paper
• Identification and purification of two distinct complexes containing the five RAD51 paralogs.

  2001cited by this paper
• Solution structure of the PHD domain from the KAP‐1 corepressor: structural determinants for PHD, RING and LIM zinc‐binding domains

  2001cited by this paper
• Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.

  2001cited by this paper
• Measuring motion on DNA by the type I restriction endonuclease EcoR124I using triplex displacement

  2000cited by this paper
• A surfeit of RAD51-like genes?

  1999cited by this paper
• XRCC3 promotes homology-directed repair of DNA damage in mammalian cells.

  1999cited by this paper
• XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages.

  1998cited by this paper

• DNA phenotyping and mapping intragenic deletion mutations in Fanconi anemia: Patterns and diagnostic inferences

  2024cites this paper
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  2022cites this paper
• The FANCC–FANCE–FANCF complex is evolutionarily conserved and regulates meiotic recombination

  2022cites this paper
• mTOR pathway and DNA damage response: A therapeutic strategy in cancer therapy.

  2021cites this paper
• Optimized structure of monoubiquitinated FANCD2 (human) at Lys 561: a theoretical approach

  2021cites this paper
• FANCG Gene

  2020cites this paper
• Identification of HLA-A/B/DRB1 alleles in Iranian patients with Fanconi anemia

  2020cites this paper
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  2020cites this paper
• Meningeal Melanocytoma - Focus on Molecular Aspects with 3 New Molecular Alterations: A Literature Review and Report of Two Cases

  2020cites this paper
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  2020cites this paper
• SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair

  2019cites this paper
• A novel frame-shift deletion in FANCF gene causing autosomal recessive Fanconi anemia: a case report

  2019cites this paper
• The Relevance of Induced Pluripotent Stem Cells for the Study of Physiological and Premature Aging

  2018cites this paper
• A Homozygous Missense Mutation in FANCA Gene in a 46,XY Female with Gonadal Dysgenesis

  2018cites this paper
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  2018cites this paper
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