Soluble CD40 ligand contributes to dendritic cell-mediated T-cell dysfunction in HIV-1 infection

No abstract is available for this paper.

• Publication year

  2015

• Venue

  AIDS (London)

• Publication date

  2015-07-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/QAD.0000000000000698PMID 26091297PMCID PMC4478195
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2009influential reference
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  2001cited by this paper
• CD40‐CD40 ligand

  2000cited by this paper
• CD40 and CD154 in cell-mediated immunity.

  1998cited by this paper
• Dendritic cells and the control of immunity

  1998cited by this paper
• Interleukin-12: a cytokine at the interface of inflammation and immunity.

  1998cited by this paper
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  1995cited by this paper

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