Centripetal modules and ancient introns.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Gene

• Publication date

  1999-09-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0378-1119(99)00292-9PMID 10570987
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Toward a resolution of the introns early/late debate: only phase zero introns are correlated with the structure of ancient proteins.

  1998cited by this paper
• The recent origins of spliceosomal introns revisited.

  1998cited by this paper
• Relationship between "proto-splice sites" and intron phases: evidence from dicodon analysis.

  1998cited by this paper
• Origin of genes.

  1997cited by this paper
• Intron positions correlate with module boundaries in ancient proteins.

  1996cited by this paper
• Testing the exon theory of genes: the evidence from protein structure.

  1994cited by this paper
• Localization of hydrogen‐bonds within modules in barnase

  1993cited by this paper
• Natural selection and the origin of jingwei, a chimeric processed functional gene in Drosophila.

  1993cited by this paper
• The exon theory of genes.

  1987cited by this paper
• Protein architecture and the origin of introns.

  1987cited by this paper
• Do genes-in-pieces imply proteins-in-pieces?

  1978cited by this paper

• Back in time to the Gly-rich prototype of the phosphate binding elementary function

  2024cites this paper
• Induced splice site mutation generates alternative intron splicing in starch synthase II (SSII) gene in rice

  2017cites this paper
• Basic units of protein structure, folding, and function.

  2017cites this paper
• Generalized EM estimation for semi-parametric mixture distributions with discretized non-parametric component

  2011cites this paper
• Evolutionary dynamics of spliceosomal intron revealed by in silico analyses of the P-Type ATPase superfamily genes

  2011cites this paper
• From protein sequence space to elementary protein modules.

  2008cites this paper
• Walking through protein sequence space.

  2007cites this paper
• A very high fraction of unique intron positions in the intron-rich diatom Thalassiosira pseudonana indicates widespread intron gain.

  2007cites this paper
• Conserved intron positions in ancient protein modules

  2007cites this paper
• Comparative genomics and evolution of alternative splicing: the pessimists' science.

  2007cites this paper
• A sequence-based model accounts largely for the relationship of intron positions to protein structural features.

  2007cites this paper
• Walking through the protein sequence space: Towards new generation of the homology modeling

  2007cites this paper
• Exon size distribution and the origin of introns

  2007cites this paper
• Formation of new genes explains lower intron density in mammalian Rhodopsin G protein-coupled receptors.

  2007cites this paper
• Conserved intron positions in ancient protein modules

  2007cites this paper
• The origin of introns and their role in eukaryogenesis: a compromise solution to the introns-early versus introns-late debate?

  2006cites this paper
• The evolution of spliceosomal introns: patterns, puzzles and progress

  2006cites this paper
• Origins and evolution of spliceosomal introns.

  2006cites this paper
• Signs of Ancient and Modern Exon-Shuffling Are Correlated to the Distribution of Ancient and Modern Domains Along Proteins

  2005influential citation
• A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage

  2004cites this paper
• A phylogeny of caenorhabditis reveals frequent loss of introns during nematode evolution.

  2004influential citation
• Phylogenetic and Exon–Intron Structure Analysis of Fungal Subtilisins: Support for a Mixed Model of Intron Evolution

  2004cites this paper
• When proteome meets genome: the alpha helix and the beta strand of proteins are eschewed by mRNA splice junctions and may define the minimal indivisible modules of protein architecture

  2004cites this paper
• When proteome meets genome : the alpha helix and the beta strand of proteins are eschewed by mRNA splice junctions and may define the minimal indivisible modules of protein architecture S

  2004cites this paper
• Functional evolution and structural conservation in chimeric cytochromes p450: calibrating a structure-guided approach.

  2004cites this paper
• The glyceraldehyde-3-phosphate dehydrogenase homologue is differentially regulated in phases of Paracoccidioides brasiliensis: molecular and phylogenetic analysis.

  2004cites this paper
• Evolutionary Aspects of Protein Structure and Folding

  2004cites this paper
• A new Drosophila spliceosomal intron position is common in plants

  2003cites this paper
• The Universe of Exons Revisited

  2003influential citation
• The Emergence of a Synthetic Theory of Intron Evolution

  2003cites this paper
• The Emergence of a Synthetic Theory of Intron Evolution

  2003cites this paper
• Recent Evidence for the Exon Theory of Genes

  2003influential citation
• Construction of block-shuffled libraries of DNA for evolutionary protein engineering: Y-ligation-based block shuffling.

  2002cites this paper
• Do introns favor or avoid regions of amino acid conservation?

  2002cites this paper
• Large-scale comparison of intron positions among animal, plant, and fungal genes

  2002cites this paper
• The signal of ancient introns is obscured by intron density and homolog number

  2002cites this paper
• Signatures of domain shuffling in the human genome.

  2002cites this paper
• Intron distribution difference for 276 ancient and 131 modern genes suggests the existence of ancient introns

  2001cites this paper
• Recombination and the Structure of Globular Proteins

  2001cites this paper
• The sequence of a 200 kb portion of a Plasmodium vivax chromosome reveals a high degree of conservation with Plasmodium falciparum chromosome 3.

  2001cites this paper
• A survey of introns in three genes of rotifers

  2001cites this paper
• [Evolutionary aspects of protein structure and folding].

  2001cites this paper
• Footprints of primordial introns on the eukaryotic genome

  2001cites this paper
• Footprints of primordial introns on the eukaryotic genome.

  2001cites this paper
• Distinct Stages of Protein Evolution as Suggested by Protein Sequence Analysis

  2001cites this paper
• Intron Dynamics and the Evolution of Integrin β-Subunit Genes: Maintenance of an Ancestral Gene Structure in the Coral, Acropora millepora

  2001influential citation
• Widespread occurrence of spliceosomal introns in the rDNA genes of ascomycetes.

  2000cites this paper