Streptococcus pneumoniae Colonization Disrupts the Microbial Community within the Upper Respiratory Tract of Aging Mice

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Infection and Immunity

• Publication date

  2016-01-19

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1128/IAI.01275-15PMID 26787714PMCID PMC4807479
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity

  2016cited by this paper
• Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age

  2015cited by this paper
• Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking

  2015cited by this paper
• Carriage of Streptococcus pneumoniae in Aged Adults with Influenza-Like-Illness

  2015cited by this paper
• Effectiveness of 23-valent pneumococcal polysaccharide vaccine against invasive disease and hospital-treated pneumonia among people aged ≥65 years: a retrospective case-control study.

  2015cited by this paper
• A Cross-Sectional Observational Study of Pneumococcal Carriage in Children, Their Parents, and Older Adults Following the Introduction of the 7-Valent Pneumococcal Conjugate Vaccine

  2015cited by this paper
• Age-Dependent Prevalence of Nasopharyngeal Carriage of Streptococcus pneumoniae before Conjugate Vaccine Introduction: A Prediction Model Based on a Meta-Analysis

  2014cited by this paper
• Streptococcus pneumoniae detects and responds to foreign bacterial peptide fragments in its environment

  2014cited by this paper
• The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition

  2014cited by this paper
• Avidity of Antibodies against Infecting Pneumococcal Serotypes Increases with Age and Severity of Disease

  2014cited by this paper
• Low Prevalence of Pneumococcal Carriage and High Serotype and Genotype Diversity among Adults over 60 Years of Age Living in Portugal

  2014cited by this paper
• Characterization of inflammatory responses during intranasal colonization with Streptococcus pneumoniae.

  2014cited by this paper
• Human Pharyngeal Microbiome May Play A Protective Role in Respiratory Tract Infections

  2014cited by this paper
• Microbial Communities in the Upper Respiratory Tract of Patients with Asthma and Chronic Obstructive Pulmonary Disease

  2014cited by this paper
• Respiratory Microbiota Dynamics following Streptococcus pneumoniae Acquisition in Young and Elderly Mice

  2014cited by this paper
• The loss of topography in the microbial communities of the upper respiratory tract in the elderly.

  2014influential reference
• Interkingdom Signaling Induces Streptococcus pneumoniae Biofilm Dispersion and Transition from Asymptomatic Colonization to Disease

  2013cited by this paper
• Impaired Innate Mucosal Immunity in Aged Mice Permits Prolonged Streptococcus pneumoniae Colonization

  2013influential reference
• Genomic Insights to Control the Emergence of Vancomycin-Resistant Enterococci

  2013cited by this paper
• Interrelationship of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus colonization within and between pneumococcal-vaccine naïve mother-child dyads

  2013cited by this paper
• Viral and Bacterial Interactions in the Upper Respiratory Tract

  2013influential reference
• Waste Not, Want Not: Why Rarefying Microbiome Data Is Inadmissible

  2013cited by this paper
• The pointy end of the stick: managing biological invasions

  2013cited by this paper
• Pneumococcal vaccination programs and the burden of invasive pneumococcal disease in Ontario, Canada, 1995-2011.

  2013cited by this paper
• Haemophilus influenzae and Streptococcus pneumoniae: living together in a biofilm.

  2013cited by this paper
• Alterations in intestinal microbiota of elderly Irish subjects post-antibiotic therapy.

  2013cited by this paper
• Density Interactions Among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the Nasopharynx of Young Peruvian Children

  2013cited by this paper
• MARCO Is Required for TLR2- and Nod2-Mediated Responses to Streptococcus pneumoniae and Clearance of Pneumococcal Colonization in the Murine Nasopharynx

  2013cited by this paper
• Gut microbiota composition correlates with diet and health in the elderly

  2012cited by this paper
• Protection from the acquisition of Staphylococcus aureus nasal carriage by cross-reactive antibody to a pneumococcal dehydrogenase

  2012cited by this paper
• Co-infection subverts mucosal immunity in the upper respiratory tract.

  2012cited by this paper
• PANDAseq: paired-end assembler for illumina sequences

  2012cited by this paper
• Aging population and future burden of pneumococcal pneumonia in the United States.

  2012cited by this paper
• Cutadapt removes adapter sequences from high-throughput sequencing reads

  2011cited by this paper
• Variability and Diversity of Nasopharyngeal Microbiota in Children: A Metagenomic Analysis

  2011cited by this paper
• Antimicrobial Susceptibilities and Serotypes of Streptococcus pneumoniae Isolates from Elderly Patients with Pneumonia and Acute Exacerbation of Chronic Obstructive Pulmonary Disease

  2011cited by this paper
• Generation of Multimillion-Sequence 16S rRNA Gene Libraries from Complex Microbial Communities by Assembling Paired-End Illumina Reads

  2011cited by this paper
• Aquarium Nitrification Revisited: Thaumarchaeota Are the Dominant Ammonia Oxidizers in Freshwater Aquarium Biofilters

  2011cited by this paper
• Unravelling the effects of the environment and host genotype on the gut microbiome

  2011cited by this paper
• Epidemiology of Streptococcus pneumoniae and Staphylococcus aureus colonization in healthy Venezuelan children

  2010cited by this paper
• Nursing home-acquired pneumonia: a 10 year single-centre experience

  2010cited by this paper
• Identification and quantification of abundant species from pyrosequences of 16S rRNA by consensus alignment

  2010cited by this paper
• Comparative Analyses of the Bacterial Microbiota of the Human Nostril and Oropharynx

  2010cited by this paper
• Lack of pneumococcal carriage in the hospitalised elderly.

  2010cited by this paper
• Within-Host Competition Drives Selection for the Capsule Virulence Determinant of Streptococcus pneumoniae

  2010cited by this paper
• Influenza A virus facilitates Streptococcus pneumoniae transmission and disease

  2010cited by this paper
• Composition, variability, and temporal stability of the intestinal microbiota of the elderly

  2010cited by this paper
• QIIME allows analysis of high-throughput community sequencing data

  2010cited by this paper
• The ecology of nasal colonization of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus: the role of competition and interactions with host's immune response

  2010cited by this paper
• Bacterial competition: surviving and thriving in the microbial jungle

  2010cited by this paper
• Age-associated inflammation and toll-like receptor dysfunction prime the lungs for pneumococcal pneumonia.

  2009cited by this paper
• Community-acquired pneumonia in elderly patients.

  2009cited by this paper
• The Descriptive Epidemiology of Streptococcus pneumoniae and Haemophilus influenzae Nasopharyngeal Carriage in Children and Adults in Kilifi District, Kenya

  2008cited by this paper
• Evaluation and Improvement of Real-Time PCR Assays Targeting lytA, ply, and psaA Genes for Detection of Pneumococcal DNA

  2007cited by this paper
• Interference between Streptococcus pneumoniae and Staphylococcus aureus: In Vitro Hydrogen Peroxide-Mediated Killing by Streptococcus pneumoniae

  2006influential reference
• Otitis media, bacterial colonization, and the smoking parent.

  2006cited by this paper
• The Role of Innate Immune Responses in the Outcome of Interspecies Competition for Colonization of Mucosal Surfaces

  2005cited by this paper
• SIVsm Quasispecies Adaptation to a New Simian Host

  2005cited by this paper
• Changing epidemiology of invasive pneumococcal disease among older adults in the era of pediatric pneumococcal conjugate vaccine.

  2005cited by this paper
• Streptococcus pneumoniae colonisation: the key to pneumococcal disease.

  2004cited by this paper
• Bacterial biota in the human distal esophagus

  2004cited by this paper
• Nasopharyngeal versus Oropharyngeal Sampling for Detection of Pneumococcal Carriage in Adults

  2004cited by this paper
• Pneumonia in the very old.

  2004cited by this paper
• Nasopharyngeal carriage of Streptococcus pneumoniae by adults and children in community and family settings.

  2004cited by this paper
• Association between carriage of Streptococcus pneumoniae and Staphylococcus aureus in Children.

  2004influential reference
• Community-acquired pneumonia

  2003cited by this paper
• Etiology of severe pneumonia in the very elderly.

  2001cited by this paper
• Oral clearance and pathogenic oropharyngeal colonization in the elderly.

  2001cited by this paper
• Community-acquired pneumonia

  1998cited by this paper
• An outbreak of multidrug-resistant pneumococcal pneumonia and bacteremia among unvaccinated nursing home residents.

  1998cited by this paper
• Reduction in mortality associated with influenza vaccine during 1989-90 epidemic.

  1995cited by this paper
• Repertoire diversity of antibody response to bacterial antigens in aged mice. II. Phosphorylcholine-antibody in young and aged mice differ in both VH/VL gene repertoire and in specificity.

  1991cited by this paper

• Evaluating the Risks of Heated Tobacco Products: Toxicological Effects on Two Selected Respiratory Bacteria and Human Lung Cells

  2025cites this paper
• Intranasal vaccination with probiotic Escherichia coli membrane vesicles displaying pneumococcal capsular polysaccharides elicits mucosal immunity

  2025cites this paper
• Interactions between bacteria in the human nasopharynx: a scoping review.

  2025cites this paper
• Regulatory functions and mechanisms of human microbiota in infectious diseases

  2024cites this paper
• Sensory neurons regulate stimulus-dependent humoral immunity in mouse models of bacterial infection and asthma

  2024cites this paper
• Inflammation of the nasal mucosa is associated with susceptibility to experimental pneumococcal challenge in older adults

  2024cites this paper
• Exploring the complexities of poultry respiratory microbiota: colonization, composition, and impact on health

  2024cites this paper
• Air pollution-associated shifts in the human airway microbiome and exposure-associated molecular events.

  2023cites this paper
• Age-Related Intestinal Dysbiosis and Enrichment of Gut-specific Bacteria in the Lung Are Associated With Increased Susceptibility to Streptococcus pneumoniae Infection in Mice

  2022cites this paper
• Understanding Human Microbiota Offers Novel and Promising Therapeutic Options against Candida Infections

  2021cites this paper
• Nasopharyngeal Microbiome

  2021cites this paper
• Antigen-Presenting Cells in the Airways: Moderating Asymptomatic Bacterial Carriage

  2021cites this paper
• Nasopharyngeal Carriage of Methicillin-Resistant Staphylococcus aureus (MRSA) among Sickle Cell Disease (SCD) Children in the Pneumococcal Conjugate Vaccine Era

  2021cites this paper
• Nasopharyngeal Carriage and Antimicrobial Susceptibility Profile of Staphylococcus aureus among Children under Five Years in Accra

  2021cites this paper
• The microbiota in pneumonia: From protection to predisposition

  2021cites this paper
• Experimental Evolution In Vivo To Identify Selective Pressures during Pneumococcal Colonization

  2020cites this paper
• Influenza-like illness is associated with high pneumococcal carriage density in Malawian children

  2020cites this paper
• B Cell Immunosenescence.

  2020cites this paper
• DYSBIOSIS, MALNUTRITION AND ENHANCED GUT-LUNG AXIS CONTRIBUTE TO AGE-RELATED RESPIRATORY DISEASES.

  2020cites this paper
• Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota

  2020cites this paper
• The alterations of tracheal microbiota and inflammation caused by different levels of ammonia exposure in broiler chickens

  2020cites this paper
• Influence of Obesity on Pneumococcus Infection Risk in the Elderly

  2019cites this paper
• Animal Models of Pneumococcal pneumonia

  2019cites this paper
• Age-Related Dysfunction in the Innate Immune Response to Lung Infections

  2019cites this paper
• Rapid Differentiation of Pneumococci And Viridans Group Streptococci by MALDI-TOF Mass Spectrometry And a Rapid Nucleic Acid Amplification Test in A Clinical Microbiology Laboratory

  2019cites this paper
• Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine

  2019cites this paper
• Isolation and Identification of Streptococcus pneumoniae Isolated From Pneumonia Patients In Thi-Qar Province/Iraq

  2019cites this paper
• A longitudinal characterization of the Non-Cystic Fibrosis Bronchiectasis airway microbiome

  2019cites this paper
• The Microbiome – The Unscheduled Parameter for Future Therapies

  2018cites this paper
• NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection.

  2018cites this paper
• Behavior of type II methanotrophic bacteria enriched from activated sludge process while utilizing ammonium as a nitrogen source

  2018cites this paper
• Modeling the within-host co-infection of influenza A virus and pneumococcus

  2018cites this paper
• Inflammaging and the Lung.

  2017cites this paper
• The lung microbiome.

  2017cites this paper
• Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice

  2017influential citation
• The nasopharyngeal microbiome.

  2017cites this paper
• Pulmonary Interleukin-17-Positive Lymphocytes Increase during Pneumocystis murina Infection but Are Not Required for Clearance of Pneumocystis

  2017cites this paper
• Innate immune responses in the ageing lung

  2016cites this paper
• Composition and immunological significance of the upper respiratory tract microbiota

  2016cites this paper