Biocompatible polymer nanoparticles for intra-cellular applications.

Polymeric styrene microspheres have a great potential at the interface of chemistry and biology. The progress of the synthetic development of multifunctional microspheres and their use as delivery agents of different biomolecules into cells is discussed. Their multifunctional properties open a wide range of applications from intracellular real-time sensors, to the use of microspheres as catalysts performing exogenous chemistry within cells.

• Publication year

  2012

• Venue

  Chimia (Basel)

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.2533/chimia.2012.237PMID 22613158
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progress and Outlook of Inorganic Nanoparticles for Delivery of Nucleic Acid Sequences Related to Orthopedic Pathologies: A Review

  2011cited by this paper
• Zeta potential mediated reaction monitoring on nano and microparticles.

  2011cited by this paper
• Nanoparticles in biological systems.

  2011cited by this paper
• The controlled display of biomolecules on nanoparticles: a challenge suited to bioorthogonal chemistry.

  2011cited by this paper
• Solid-phase synthesis of arginine-based double-tailed cationic lipopeptides: potent nucleic acid carriers.

  2011cited by this paper
• Palladium-mediated intracellular chemistry.

  2011cited by this paper
• Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles.

  2011cited by this paper
• Novel strategy for microsphere-mediated DNA transfection.

  2011cited by this paper
• Potent Delivery of Functional Proteins into Mammalian Cells in Vitro and in Vivo Using a Supercharged Protein

  2010cited by this paper
• What the cell "sees" in bionanoscience.

  2010cited by this paper
• Glycopeptide dendrimer colchicine conjugates targeting cancer cells.

  2010cited by this paper
• Knocking (anti)-sense into cells: the microsphere approach to gene silencing.

  2009cited by this paper
• Microsphere‐Mediated Protein Delivery into Cells

  2009cited by this paper
• Metalloproteins and metal sensing

  2009cited by this paper
• Microsphere-based tracing and molecular delivery in embryonic stem cells.

  2009cited by this paper
• Microspheres as a vehicle for biomolecule delivery to neural stem cells.

  2009cited by this paper
• Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

  2008cited by this paper
• pH sensing in living cells using fluorescent microspheres.

  2008cited by this paper
• The present and future of nanotechnology in human health care.

  2007cited by this paper
• Microsphere-based real-time calcium sensing.

  2006cited by this paper
• Loading of hydrophobic materials into polymer particles: implications for fluorescent nanosensors and drug delivery.

  2005cited by this paper
• Dendrimers in gene delivery.

  2005cited by this paper
• Bead‐Based Cellular Analysis, Sorting and Multiplexing

  2005cited by this paper
• Cell Penetrating Peptides in Drug Delivery

  2004cited by this paper
• Ratiometric intracellular calcium imaging in the isolated beating rat heart using indo-1 fluorescence.

  2004cited by this paper
• Solid-phase synthesis of 89 polyamine-based cationic lipids for DNA delivery to mammalian cells.

  2004cited by this paper
• Physics and Chemistry of Interfaces

  2003cited by this paper
• Protein delivery by subviral particles of human cytomegalovirus

  2003cited by this paper
• Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

  2001cited by this paper
• Breaking the barrier: methods for reversible permeabilization of cellular membranes.

  1997cited by this paper
• Intracellular pH.

  1981cited by this paper
• Tissue sulfhydryl groups.

  1959cited by this paper

• Vasoactive Intestinal Peptide (VIP) Nanoparticles for Diagnostics and for Controlled and Targeted Drug Delivery.

  2015cites this paper
• Transition-metal-mediated uncaging in living human cells—an emerging alternative to photolabile protecting groups.

  2015cites this paper