Troglitazone selectively inhibits glyoxalase I gene expression

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Diabetologia

• Publication date

  2001-11-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s001250100004PMID 11719831
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Redox Regulation of Nuclear Factor Kappa B: Therapeutic Potential for Attenuating Inflammatory Responses

  2000cited by this paper
• CYP3A4 allelic variants with amino acid substitutions in exons 7 and 12: Evidence for an allelic variant with altered catalytic activity

  2000cited by this paper
• Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

  2000cited by this paper
• Hepatic injury due to troglitazone.

  2000cited by this paper
• Troglitazone-induced fulminant hepatic failure. Acute Liver Failure Study Group.

  2000cited by this paper
• Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration

  2000cited by this paper
• Thioredoxin reductase and glutathione synthesis is upregulated by t‐butylhydroquinone in cortical astrocytes but not in cortical neurons

  2000cited by this paper
• A systematic approach to evaluate the modification of lens proteins by glycation-induced crosslinking.

  1999cited by this paper
• Genomic sequence of human glyoxalase-I: analysis of promoter activity and its regulation.

  1999cited by this paper
• Troglitazone and pioglitazone attenuate agonist‐dependent Ca2+ mobilization and cell proliferation in vascular smooth muscle cells

  1999cited by this paper
• Rosiglitazone

  1999cited by this paper
• Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes.

  1999cited by this paper
• Metformin reduces systemic methylglyoxal levels in type 2 diabetes.

  1999cited by this paper
• Troglitazone inhibits expression of the phosphoenolpyruvate carboxykinase gene by an insulin-independent mechanism.

  1999cited by this paper
• Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.

  1998cited by this paper
• Cell activation by glycated proteins. AGE receptors, receptor recognition factors and functional classification of AGEs.

  1998cited by this paper
• Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene.

  1998cited by this paper
• Functional Antagonism between CCAAT/Enhancer Binding Protein-α and Peroxisome Proliferator-activated Receptor-γ on the Leptin Promoter*

  1997cited by this paper
• Regulation of human gamma-glutamylcysteine synthetase: co-ordinate induction of the catalytic and regulatory subunits in HepG2 cells.

  1997cited by this paper
• Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance.

  1997cited by this paper
• Troglitazone has a scavenging effect on reactive oxygen species.

  1997cited by this paper
• Selenium and the thioredoxin and glutaredoxin systems.

  1997cited by this paper
• The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene*

  1997cited by this paper
• Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma.

  1996cited by this paper
• Glutathione release and catabolism during energy substrate restriction in astrocytes.

  1996cited by this paper
• Low Glutathione and High Iron Govern the Susceptibility of Oligodendroglial Precursors to Oxidative Stress

  1996cited by this paper
• Thiazolidinediones in the Treatment of Insulin Resistance and Type II Diabetes

  1996cited by this paper
• Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

  1996cited by this paper
• 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma.

  1995cited by this paper
• Glyoxalase I in detoxification: studies using a glyoxalase I transfectant cell line.

  1995cited by this paper
• Thioredoxin and thioredoxin reductase.

  1995cited by this paper
• Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone.

  1994cited by this paper
• Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications.

  1994cited by this paper
• Antihypertensive effects of CS-045 treatment in obese Zucker rats.

  1993cited by this paper
• Modification of the glyoxalase system in streptozotocin-induced diabetic rats. Effect of the aldose reductase inhibitor Statil.

  1993cited by this paper
• Cloning and characterization of human colon glyoxalase-I.

  1993cited by this paper
• 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO.

  1991cited by this paper
• Population genetics of human glyoxalases

  1991cited by this paper
• The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life.

  1990cited by this paper
• Depressant effect of very low levels of aflatoxin B1 on mouse glyoxylase-I activity and methylglyoxal disposal.

  1990cited by this paper
• Three models of free radical-induced cell injury.

  1989cited by this paper
• Erythrocyte glyoxalase activity in genetically obese (ob/ob) and streptozotocin diabetic mice.

  1989cited by this paper
• Glyoxalase activity in human red blood cells fractioned by age.

  1989cited by this paper
• Characterization of New Oral Antidiabetic Agent CS-045: Studies in KK and ob/ob Mice and Zucker Fatty Rats

  1988cited by this paper
• Measurement of protein using bicinchoninic acid.

  1985cited by this paper
• Accelerated age-related browning of human collagen in diabetes mellitus.

  1984cited by this paper
• Oleic acid promotes the activation and translocation of phosphatidate phosphohydrolase from the cytosol to particulate fractions of isolated rat hepatocytes.

  1984cited by this paper
• Glutathione.

  1983cited by this paper
• Properties of a clonal muscle cell line from rat heart.

  1976cited by this paper

• Methylglyoxal in Cancer: Bidirectional Regulatory Networks and Precision Intervention—From Metabolic Reprogramming to Cross-Disease Synergistic Targeting

  2025cites this paper
• The Role of Glyoxalase-I (Glo-I), Advanced Glycation Endproducts (AGEs), and Their Receptor (RAGE) in Chronic Liver Disease and Hepatocellular Carcinoma (HCC)

  2017cites this paper
• Impact of Glyoxalase-I (Glo-I) and Advanced Glycation End Products (AGEs) in Chronic Liver Disease

  2017cites this paper
• Methylglyoxal-derived stress: An emerging biological factor involved in the onset and progression of cancer.

  2017cites this paper
• Methylglyoxal, the dark side of glycolysis

  2015cites this paper
• Methylglyoxal Mediates Adipocyte Proliferation by Increasing Phosphorylation of Akt1

  2012cites this paper
• Thiazolidinediones in Type 2 Diabetes Mellitus

  2012cites this paper
• The role of glyoxalases for sugar stress and aging, with relevance for dyskinesia, anxiety, dementia and Parkinson's disease

  2011cites this paper
• Role of the Glyoxalase System in Astrocyte-Mediated Neuroprotection

  2011cites this paper
• Troglitazone Reduces Glyoxalase I Protein Expression in Glioma and Potentiates the Effects of Chemotherapeutic Agents

  2010cites this paper
• The Effect of Troglitazone on Thermal Sensitivity in Uterine Cervix Cancer Cells

  2010cites this paper
• Troglitazone reverses the multiple drug resistance phenotype in cancer cells

  2009cites this paper
• Methylglyoxal and Insulin Resistance

  2008cites this paper
• Heat‐shock protein 27 is a major methylglyoxal‐modified protein in endothelial cells

  2006cites this paper
• The pro-oxidant role of methylglyoxal in mesenteric artery smooth muscle cells.

  2005cites this paper
• Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells.

  2005cites this paper
• Troglitazone overcomes doxorubicin-resistance in resistant K562 leukemia cells

  2005cites this paper
• Beneficial and deleterious effects of rosiglitazone on hypertension development in spontaneously hypertensive rats.

  2004cites this paper
• Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence.

  2003cites this paper
• Troglitazone stimulates IGF-binding protein-1 by a PPAR gamma-independent mechanism.

  2003cites this paper
• Troglitazone reduces heat shock protein 70 content in primary rat hepatocytes by a ubiquitin proteasome independent mechanism.

  2003cites this paper
• Troglitazone stimulates IGF-binding protein-1 by a PPARγ-independent mechanism

  2003cites this paper
• Regulation of the glyoxalase pathway in human brain microvascular endothelium: effects of troglitazone and tertiary butylhydroperoxide.

  2002cites this paper
• Current literature in diabetes.

  2002cites this paper
• Increased Methylglyoxal and Oxidative Stress in Hypertensive Rat Vascular Smooth Muscle Cells

  2002cites this paper