Regulation of connexin36 gap junction channels by n‐alkanols and arachidonic acid

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Physiology

• Publication date

  2013-04-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1113/jphysiol.2013.250910PMID 23420660PMCID PMC3634521
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Synergy between Electrical Coupling and Membrane Properties Promotes Strong Synchronization of Neurons of the Mesencephalic Trigeminal Nucleus

  2012influential reference
• The Role of Gap Junction Channels During Physiologic and Pathologic Conditions of the Human Central Nervous System

  2012cited by this paper
• Connexin-36 Gap Junctions Regulate In Vivo First- and Second-Phase Insulin Secretion Dynamics and Glucose Tolerance in the Conscious Mouse

  2012cited by this paper
• Stochastic 16-state model of voltage gating of gap-junction channels enclosing fast and slow gates.

  2012cited by this paper
• Human Connexin Channel Specificity of Classical and New Gap Junction Inhibitors

  2012influential reference
• pH‐dependent modulation of connexin‐based gap junctional uncouplers

  2011cited by this paper
• Gap junctions and other mechanisms of cell–cell communication regulate basal insulin secretion in the pancreatic islet

  2011influential reference
• pH-dependent modulation of voltage gating in connexin45 homotypic and connexin45/connexin43 heterotypic gap junctions

  2010influential reference
• A stochastic four-state model of contingent gating of gap junction channels containing two "fast" gates sensitive to transjunctional voltage.

  2009influential reference
• Gating, permselectivity and pH‐dependent modulation of channels formed by connexin57, a major connexin of horizontal cells in the mouse retina

  2009influential reference
• Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.

  2009influential reference
• Efficient culture of CD8(+) T cells from the islets of NOD mice and their use for the study of autoreactive specificities.

  2008cited by this paper
• Cell coupling in mouse pancreatic β-cells measured in intact islets of Langerhans

  2008influential reference
• A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells.

  2008cited by this paper
• Molecular basis of voltage dependence of connexin channels: an integrative appraisal.

  2007cited by this paper
• Connexin channel permeability to cytoplasmic molecules.

  2007influential reference
• Modeling bovine serum albumin binding of flavor compounds (alcohols, aldehydes, esters, and ketones) as a function of molecular properties.

  2007cited by this paper
• Inhibitors of Brain Phospholipase A2 Activity: Their Neuropharmacological Effects and Therapeutic Importance for the Treatment of Neurologic Disorders

  2006influential reference
• Endoplasmic reticulum: one continuous network compartmentalized by extrinsic cues.

  2005influential reference
• Biophysical evidence that connexin-36 forms functional gap junction channels between pancreatic mouse beta-cells.

  2005influential reference
• Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release.

  2005cited by this paper
• Arachidonic acid closes gap junction channels in rat lacrimal glands

  2004cited by this paper
• Regulation of the specific release of arachidonic acid by cytosolic phospholipase A2.

  2004cited by this paper
• Gap junction channel gating.

  2004cited by this paper
• Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells.

  2004cited by this paper
• Chemical gating of gap junction channels; roles of calcium, pH and calmodulin.

  2004cited by this paper
• Conformational changes in surface structures of isolated connexin 26 gap junctions

  2002cited by this paper
• Prospects for rational development of pharmacological gap junction channel blockers.

  2002cited by this paper
• Epidermal Growth Factor Induces p11 Gene and Protein Expression and Down-regulates Calcium Ionophore-induced Arachidonic Acid Release in Human Epithelial Cells*

  2002cited by this paper
• Gating properties of gap junction channels assembled from connexin43 and connexin43 fused with green fluorescent protein.

  2001cited by this paper
• Emerging issues of connexin channels: biophysics fills the gap

  2001influential reference
• How to close a gap junction channel. Efficacies and potencies of uncoupling agents.

  2001cited by this paper
• Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture

  2001cited by this paper
• Cx36 preferentially connects beta-cells within pancreatic islets.

  2000cited by this paper
• Clustering of connexin 43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells.

  2000influential reference
• Phospholipase A(2)s in cell injury and death.

  2000influential reference
• Functional Expression of the Murine Connexin 36 Gene Coding for a Neuron-Specific Gap Junctional Protein

  2000influential reference
• Cell coupling modulates the contraction of fibroblast‐populated collagen lattices

  2000cited by this paper
• Regulation and inhibition of phospholipase A2.

  1999influential reference
• Rapid and Direct Effects of pH on Connexins Revealed by the Connexin46 Hemichannel Preparation

  1999cited by this paper
• Functional Properties of Channels Formed by the Neuronal Gap Junction Protein Connexin36

  1999cited by this paper
• Molecular Determinants of Electrical Rectification of Single Channel Conductance in Gap Junctions Formed by Connexins 26 and 32

  1999cited by this paper
• Regulation of arachidonic acid release and cytosolic Phospholipase A2 activation

  1999cited by this paper
• Chemical requirements for inhibition of gap junction communication by the biologically active lipid oleamide.

  1998cited by this paper
• Multi-metal binding site of serum albumin.

  1998cited by this paper
• Inhibition of Choline Acetyltransferase Activity by Serum Albumin Modified with Octanoic Acid and Other Fatty Acids

  1998cited by this paper
• Modulation of arachidonic acid release and membrane fluidity by albumin in vascular smooth muscle and endothelial cells.

  1998influential reference
• Modulation of cardiac gap junctions: the mode of action of arachidonic acid.

  1997cited by this paper
• A micro-scale method for determining relative metal-binding affinities of proteins

  1997cited by this paper
• Long-chain n-alkanols and arachidonic acid interfere with the Vm-sensitive gating mechanism of gap junction channels

  1997cited by this paper
• Tamoxifen inhibits the release of arachidonic acid stimulated by thapsigargin in estrogen receptor-negative A549 cells.

  1997influential reference
• Oleic Acid Inhibits Gap Junction Permeability and Increases Glucose Uptake in Cultured Rat Astrocytes

  1997cited by this paper
• Control of arachidonate levels within inflammatory cells.

  1996cited by this paper
• Modification of gap junction conductance by divalent cations and protons in neonatal rat heart cells.

  1995cited by this paper
• Albumin reduces basement membrane hydraulic conductance in part due to arginyl side groups.

  1995cited by this paper
• Inhibition of gap junctional communication by polyunsaturated fatty acids in WB cells: evidence that connexin 43 is not hyperphosphorylated.

  1995cited by this paper
• Heart gap junction preparations reveal hemiplaques by atomic force microscopy.

  1995cited by this paper
• Binding of arachidonate and oleate to bovine serum albumin.

  1994cited by this paper
• Connexin37 forms high conductance gap junction channels with subconductance state activity and selective dye and ionic permeabilities.

  1994cited by this paper
• Properties of a nonjunctional current expressed from a rat connexin46 cDNA in Xenopus oocytes

  1993cited by this paper
• Chick connexin-56, a novel lens gap junction protein. Molecular cloning and functional expression.

  1993cited by this paper
• Oleic acid differentially affects gap junction-mediated communication in heart and vascular smooth muscle cells.

  1993cited by this paper
• Limitations of the dual voltage clamp method in assaying conductance and kinetics of gap junction channels.

  1992cited by this paper
• Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies

  1992cited by this paper
• Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet beta cells.

  1992cited by this paper
• Locations of the three primary binding sites for long-chain fatty acids on bovine serum albumin.

  1991cited by this paper
• Uncoupling of cardiac cells by fatty acids: structure-activity relationships.

  1991influential reference
• Connexin32 gap junction channels in stably transfected cells: unitary conductance.

  1991cited by this paper
• Metabolic coupling and ligand-stimulated meiotic maturation in the mouse oocyte-cumulus cell complex.

  1991cited by this paper
• Effects of arachidonic acid on the gap junctions of neonatal rat heart cells

  1990cited by this paper
• Structure-activity relations of the cardiac gap junction channel.

  1990cited by this paper
• Lipids in gap junction assembly and function

  1990cited by this paper
• Rapid confirmation and revision of the primary structure of bovine serum albumin by ESIMS and Frit-FAB LC/MS.

  1990cited by this paper
• Effects of n‐alcohols on junctional coupling and amylase secretion of pancreatic acinar cells

  1989cited by this paper
• Single-channel events and gating behavior of the cardiac gap junction channel.

  1988cited by this paper
• Regulation of Pancreatic Exocrine Function: A Role for Cell‐to‐Cell Communication?

  1987cited by this paper
• Location of long chain fatty acid-binding sites of bovine serum albumin by affinity labeling.

  1986cited by this paper
• The effects of native and modified bovine serum albumin on the permeability of frog mesenteric capillaries.

  1985influential reference
• Arachidonate release and phosphatidic acid turnover in stimulated human platelets.

  1983cited by this paper
• Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

  1975cited by this paper
• Studies on the chemical modification of arginine. I. The reaction of 1,2-cyclohexanedione with arginine and arginyl residues of proteins.

  1967cited by this paper
• General Chemistry:

  1936cited by this paper
• for A MicroScale Method Determining Relative Metal-Binding Affinities of Proteins

  year unknowncited by this paper

• Dose- and Time-Dependent Modulation of Cx43 and Cx45 Expression and Gap Junction Conductance by Resveratrol

  2026cites this paper
• Preference of short isoprene-repeat terpenes for Cx43 gap junctions compared with cardiac Na+ and Ca2+ channels: application for cardiac ephaptic transmission research.

  2025cites this paper
• Electrostatic Interaction Determines the Docking Specificity and the Formation of Functional Cx36 Gap Junction Channels

  2025cites this paper
• The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact

  2024cites this paper
• The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact

  2023cites this paper
• Mefloquine-induced conformational shift in Cx36 N-terminal helix leading to channel closure mediated by lipid bilayer

  2023influential citation
• When microscopy and electrophysiology meet connectomics—Steve Massey’s contribution to unraveling the structure and function of the rod/cone gap junction

  2023influential citation
• Cryo-EM structures of human Cx36/GJD2 neuronal gap junction channel

  2023cites this paper
• Insect Gap Junctions Could Be a Potential Target for Pest Management

  2022cites this paper
• The Amino Terminal Domain and Modulation of Connexin36 Gap Junction Channels by Intracellular Magnesium Ions

  2022cites this paper
• Prostaglandin E2 Enhances Gap Junctional Intercellular Communication in Clonal Epithelial Cells

  2021influential citation
• Analysis of rod/cone gap junctions from the reconstruction of mouse photoreceptor terminals

  2021cites this paper
• Role of Lipid Metabolism and Signaling in Mammalian Oocyte Maturation, Quality, and Acquisition of Competence

  2021cites this paper
• Beyond plasticity: the dynamic impact of electrical synapses on neural circuits

  2019cites this paper
• Molecular basis for potentiation of Cx36 gap junction channel conductance by n-alcohols and general anesthetics

  2018cites this paper
• 8 – Molecular Organization, Gating, and Function of Connexin-Based Gap Junction Channels and Hemichannels

  2018cites this paper
• The SH3-binding domain of Cx43 participates in loop/tail interactions critical for Cx43-hemichannel activity

  2018cites this paper
• The electrical synapse: Molecular complexities at the gap and beyond

  2017cites this paper
• Potential role of polyunsaturated fatty acids, with particular regard to the signaling pathways of arachidonic acid and its derivatives in the process of maturation of the oocytes: Contemporary review.

  2017cites this paper
• Connexins in Cardiovascular and Neurovascular Health and Disease: Pharmacological Implications

  2017cites this paper
• Regulation of Connexin-Based Channels by Fatty Acids

  2017cites this paper
• From Neuron Biophysics to Orientation Selectivity in Electrically Coupled Networks of Neocortical L2/3 Large Basket Cells

  2016cites this paper
• Reverberation of excitation in neuronal networks interconnected through voltage-gated gap junction channels

  2016cites this paper
• Gap Junction Blockers: An Overview of their Effects on Induced Seizures in Animal Models

  2016influential citation
• Functional Properties of Dendritic Gap Junctions in Cerebellar Golgi Cells

  2016cites this paper
• Stochastic Model of Gap Junctions Exhibiting Rectification and Multiple Closed States of Slow Gates.

  2016cites this paper
• Linoleic acid permeabilizes gastric epithelial cells by increasing connexin 43 levels in the cell membrane via a GPR40- and Akt-dependent mechanism.

  2016cites this paper
• The role of neural connexins in HeLa cell mobility and intercellular communication through tunneling tubes

  2016cites this paper
• TWO-COLOR FLUORESCENT ANALYSIS OF CONNEXIN 36 TURNOVER AND TRAFFICKING – RELATIONSHIP TO FUNCTIONAL PLASTICITY

  2015cites this paper
• New insights into the role of connexins in pancreatic islet function and diabetes

  2014cites this paper
• Activation, Permeability, and Inhibition of Astrocytic and Neuronal Large Pore (Hemi)channels*♦

  2014cites this paper
• Effects of small interfering RNA interference of connexin 37 on subcutaneous gastric tumours in mice.

  2014cites this paper
• ( Hemi ) channels Astrocytic and Neuronal Large Pore Activation , Permeability , and Inhibition of Neurobiology

  2014cites this paper
• Molecular Determinants of Magnesium-Dependent Synaptic Plasticity at Electrical Synapses Formed by Connexin36

  2014cites this paper
• Turnover rate of the neuronal connexin Cx36 in HeLa cells

  2013cites this paper