Artemin crystal structure reveals insights into heparan sulfate binding.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biochemistry

• Publication date

  2006-05-13

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/BI060035XPMID 16734417
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Glial cell line-derived neurotrophic factor (GDNF) receptor alpha-1 (GFR alpha 1) is highly selective for GDNF versus artemin.

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• The structure of GFRα1 domain 3 reveals new insights into GDNF binding and RET activation

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• Multiple actions of systemic artemin in experimental neuropathy

  2003cited by this paper
• Structural Determinants of Heparan Sulphate Modulation of GDNF Signalling

  2003cited by this paper
• Heparin facilitates glial cell line-derived neurotrophic factor signal transduction

  2002cited by this paper
• Artemin is a vascular-derived neurotropic factor for developing sympathetic neurons.

  2002cited by this paper
• Signalling by glial cell line-derived neurotrophic factor (GDNF) requires heparan sulphate glycosaminoglycan

  2002cited by this paper
• In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin.

  2000cited by this paper
• Functional Mapping of Receptor Specificity Domains of Glial Cell Line-derived Neurotrophic Factor (GDNF) Family Ligands and Production of GFRα1 RET-specific Agonists*

  2000cited by this paper
• Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

  2000cited by this paper
• Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex.

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  1999cited by this paper
• Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. Existence and tissue-specific expression of different splice variants.

  1999cited by this paper
• GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion.

  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
• Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivo.

  1998cited by this paper
• Persephin, a novel neurotrophic factor related to GDNF and neurturin.

  1998cited by this paper
• Glycosaminoglycan‐protein interactions: definition of consensus sites in glycosaminoglycan binding proteins

  1998cited by this paper
• Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex.

  1998cited by this paper
• Hepatocyte Growth Factor/Scatter Factor Binds with High Affinity to Dermatan Sulfate*

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  1997cited by this paper
• X-ray structure of glial cell-derived neurotrophic factor at 1.9 Å resolution and implications for receptor binding

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  1997cited by this paper
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  2020cites this paper
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• Investigating the Role of Artemin Glycosylation

  2016cites this paper
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  2016cites this paper
• ON THE MECHANISMS OF NEURAL DEVELOPMENT IN THE VENTRAL TELENCEPHALON

  2016cites this paper
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• Artemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crush

  2015cites this paper
• Neurotrophic factors GDNF and NRTN : from basic properties to clinical trials

  2014cites this paper
• Neurotrophic factors GDNF and NRTN : from basic properties to clinical trials

  2014cites this paper
• The DAN family: Modulators of TGF‐β signaling and beyond

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• Structural studies of GDNF family ligands with their receptors-Insights into ligand recognition and activation of receptor tyrosine kinase RET.

  2013cites this paper
• Artemin causes hypersensitivity to warm sensation similar to warmth-provoked pruritus in atopic dermatitis

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• Oncogenic functions of ARTEMIN in ER negative mammary carcinoma

  2013cites this paper
• Glial cell line-derived neurotrophic factor: Characterization of mammalian posttranslational modifications

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