Correlation of contractile dysfunction with oxidative energy production and tissue high energy phosphate stores during partial coronary flow disruption in rabbit heart.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Journal of Clinical Investigation

• Publication date

  1988-07-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1172/JCI113606PMID 3392219PMCID PMC303480
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Myocardial energy production and consumption remain balanced during positive inotropic stimulation when coronary flow is restricted to basal rates in rabbit heart.

  1987cited by this paper
• Contractile failure and high-energy phosphate turnover during hypoxia: 31P-NMR surface coil studies in living rat.

  1987cited by this paper
• Mechanism of Early Contractile Failure During Hypox in Intact Ferret Heart: Evidence for Modulation of Maximal Ca2+‐Activated Force by Inorganic Phosphate

  1986cited by this paper
• Biochemical mechanisms of acute contractile failure in the hypoxic rat heart.

  1986cited by this paper
• Effect of erythrocyte storage and oxyhemoglobin affinity changes on cardiac function.

  1985cited by this paper
• Role of Glycolytic Products in Damage to Ischemic Myocardium: Dissociation of Adenosine Triphosphate Levels and Recovery of Function of Reperfused Ischemic Hearts

  1984cited by this paper
• Regulation of cardiac contractile proteins. Correlations between physiology and biochemistry.

  1984cited by this paper
• Effect of Exercise on the Relationship between Myocardial Blood Flow and Systolic Wall Thickening in Dogs with Acute Coronary Stenosis

  1983cited by this paper
• Acute Alterations in Left Ventricular Diastolic Chamber Stiffness: Role of the “Erectile” Effect of Coronary Arterial Pressure and Flow in Normal and Damaged Hearts

  1982cited by this paper
• Correlation between Acute Reductions in Myocardial Blood Flow and Function in Conscious Dogs

  1980cited by this paper
• Heart creatine kinase : the integration of isozymes for energy distribution

  1980cited by this paper
• An improved isolated heart preparation for external assessment of myocardial metabolism.

  1979cited by this paper
• Oxygen deprivation and early myocardial contractile failure: a reassessment of the possible role of adenosine triphosphate.

  1979cited by this paper
• Segment stroke work and metabolism depend on coronary blood flow in the pig.

  1978influential reference
• Early changes in regional and global left ventricular function induced by graded reductions in regional coronary perfusion.

  1977cited by this paper
• Acute changes in high energy phosphates, nucleotide derivatives, and contractile force in ischaemic and nonischaemic canine myocardium following coronary occlusion.

  1976cited by this paper
• Changes in Coronary Venous Inosine Concentration and Myocardial Wall Thickening during Regional Ischemia in the Pig

  1974cited by this paper
• Analysis and Correction of Pressure Wave Distortion in Fluid‐Filled Catheter Systems

  1974cited by this paper
• Correlation between changes in the endogenous energy stores and myocardial function due to hypoxia in the isolated perfused rat heart.

  1972cited by this paper
• Functional compartmentation of ATP and creatine phosphate in heart muscle.

  1970cited by this paper
• Editorial: the early "pump" failure of the ischemic heart.

  1969cited by this paper
• Effects of interrupted coronary flow upon myocardial metabolism and contractility.

  1968cited by this paper
• Effects of Interrupted Coronary Flow Upon Myocardial Metabolism and Contractility

  1968cited by this paper
• Myocardial High Energy Phosphate Stores in Acutely Induced Hypoxic Heart Failure

  1966cited by this paper
• Effects of Experimental Congestive Heart Failure, Ouabain, and Asphyxia on the High‐Energy Phosphate and Creatine Content of the Guinea Pig Heart

  1962cited by this paper
• Thermodynamics and the interpretation of biological heat measurements.

  1960cited by this paper
• Thermodynamics and the interpretation of biological heat measurements.

  1960cited by this paper

• A computational model of myocardial microcirculation including interstitial flow

  2017influential citation
• THE ROLE OF NON-INVASIVE TESTS IN THE MANAGEMENT OF ISCHEMIC HEART DISEASE. ASSESSMENT OF MYOCARDIAL VIABILITY

  2016cites this paper
• Kinetic analysis of 18F-fluorodihydrorotenone as a deposited myocardial flow tracer: comparison to 201Tl.

  2004cites this paper
• Kinetic analysis of 18F-fluorodihydrorotenone as a deposited myocardial flow tracer: Comparison to thallium-201.

  2004cites this paper
• Kinetic Analysis of 18 F-Fluorodihydrorotenone as a Deposited Myocardial Flow Tracer : Comparison to 201 Tl

  2004cites this paper
• Flow heterogeneity following global no-flow ischemia in isolated rabbit heart.

  2003cites this paper
• Oxygen Modulation of Superoxide Radical Injury in the Krebs-Perfused, Isolated Rabbit Heart

  2002cites this paper
• Kinetic Analysis of 125 I-Iodorotenone as a Deposited Myocardial Flow Tracer: Comparison with 99m Tc-Sestamibi

  2001cites this paper
• Kinetic analysis of 125I-iodorotenone as a deposited myocardial flow tracer: comparison with 99mTc-sestamibi.

  2001influential citation
• Myocardial oxygenation and high-energy phosphate levels during graded coronary hypoperfusion.

  2001cites this paper
• Cardioplegia sangüínea anterógrada intermitente normotérmica e hipotérmica: estudo comparativo em corações agudamente isquêmicos de coelhos

  2000cites this paper
• Effects of critical coronary stenosis on global systolic left ventricular function quantified by pressure-volume relations during dobutamine stress in the canine heart.

  1998cites this paper
• Papel de las exploraciones no invasivas en el manejo de la cardiopatía isquémica III. Estimación de la viabilidad miocárdica

  1997cites this paper
• Effects of acetate on energy metabolism and function in the isolated perfused rat heart.

  1997cites this paper
• Inhibition of myocardial crossbridge cycling by hypoxic endothelial cells: a potential mechanism for matching oxygen supply and demand?

  1997cites this paper
• [Role of noninvasive examinations in the management of ischemic heart disease. III. Assessment of myocardial viability].

  1997cites this paper
• Kinetic analysis of rubidium and thallium as deposited myocardial blood flow tracers in isolated rabbit heart.

  1997cites this paper
• Proportionate reversible decreases in systolic function and myocardial oxygen consumption after modest reductions in coronary flow: hibernation versus stunning.

  1997cites this paper
• Effects of low-flow ischemia on the positive inotropic action of angiotensin II in isolated rabbit and rat hearts.

  1997cites this paper
• Estimation of nonmechanical VO2 in isolated rabbit heart: comparison of mechanical unloading and BDM method.

  1997cites this paper
• Myocardial viability.

  1996cites this paper
• Transmural channels can protect ischemic tissue. Assessment of long-term myocardial response to laser- and needle-made channels.

  1996cites this paper
• Rapid shortening during relaxation increases activation and improves systolic performance.

  1996cites this paper
• Beneficial effects of felodipine on myocardial and coronary function during low-flow ischemia and reperfusion

  1996cites this paper
• Effect of treppe on isovolumic function in the isolated blood-perfused mouse heart.

  1996cites this paper
• Stability of high-energy phosphates in right ventricle: myocardial energetics during right coronary hypotension.

  1996cites this paper
• Cardioprotective Effects of Red Blood Cells on Ischemia and Reperfusion Injury in Isolated Rat Heart: Release of Nitric Oxide as a Potential Mechanism

  1996cites this paper
• Myocardial oxygenation and contractile function during graded reduction of coronary flow.

  1996cites this paper
• Vergleich dreier gängiger Kardioplegielösungen—Untersuchungen am isolierten Herzen zur Myokardprotektion während Ischämie und Reperfusion

  1996cites this paper
• Left ventricular mechanoenergetics under altered coronary perfusion in guinea pig hearts.

  1995cites this paper
• Critical role of energy supply and glycolysis during short-term hibernation

  1995cites this paper
• Reduced aerobic metabolic efficiency in postischemic myocardium dysfunction in rats: role of aging.

  1995cites this paper
• Gradual onset of myocardial ischemia results in reduced myocardial infarction. Association with reduced contractile function and metabolic downregulation.

  1995cites this paper
• Effects of perfusion pressure on intracellular calcium, energetics, and function in perfused rat hearts.

  1993cites this paper
• Effects of brief repetitive ischemia on contractility, relaxation, and coronary flow. Exaggerated postischemic diastolic dysfunction in pressure-overload hypertrophy.

  1993cites this paper
• Regulation of cardiac energy turnover by coronary flow: a 31P-NMR study.

  1993cites this paper
• Exacerbation of ischemic dysfunction by angiotensin II in red cell-perfused rabbit hearts. Effects on coronary flow, contractility, and high-energy phosphate metabolism.

  1992cites this paper
• Molecular regulation of cardiac myocyte adaptations to chronic hypoxia.

  1992cites this paper
• The response to ischemia in blood perfused vs. crystalloid perfused isolated rat heart preparations.

  1992cites this paper
• Reperfusion of hibernating myocardium: contractile function, high-energy phosphate content, and myocyte injury after 3 hours of sublethal ischemia and 3 hours of reperfusion in the canine model.

  1992cites this paper
• Cardiac contractile dysfunction during mild coronary flow reductions is due to an altered calcium-pressure relationship in rat hearts.

  1992cites this paper
• Exacerbation of left ventricular ischemic diastolic dysfunction by pressure-overload hypertrophy. Modification by specific inhibition of cardiac angiotensin converting enzyme.

  1992cites this paper
• Correlation of contractile dysfunction and abnormal tissue energy metabolism during hypoperfusion with norepinephrine in isolated rat hearts: differences between normal and diabetic hearts.

  1992cites this paper
• Effects of Ischemia, Hypoxia, and Acidosis on Cardiac Systolic and Diastolic Function, and Glycolytic Metabolism in Normal and Hypertrophied Hearts

  1992cites this paper
• The effect of flow on technetium-99m-teboroxime (SQ30217) and thallium-201 extraction and retention in rabbit heart.

  1991cites this paper
• Cardiac contractile function, oxygen consumption rate and cytosolic phosphates during inhibition of electron flux by amytal--a 31P-NMR study.

  1991cites this paper
• Protective effect of increased glycolytic substrate against systolic and diastolic dysfunction and increased coronary resistance from prolonged global underperfusion and reperfusion in isolated rabbit hearts perfused with erythrocyte suspensions.

  1991cites this paper
• A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart.

  1991cites this paper
• Response to myocardial ischemia as a regulated process.

  1991cites this paper
• Effect of graded reductions of coronary pressure and flow on myocardial metabolism and performance: a model of "hibernating" myocardium.

  1991cites this paper
• Should 18F deoxyglucose scans be indicated for care of patients with coronary artery disease?

  1991cites this paper
• Correlation between transmural high energy phosphate levels and myocardial blood flow in the presence of graded coronary stenosis.

  1990cites this paper
• Technetium-99m hexakis 2-methoxy-2-isobutyl isonitrile and thallium-201 extraction, washout, and retention at varying coronary flow rates in rabbit heart.

  1990cites this paper
• Relationship between myocardial metabolites and contractile abnormalities during graded regional ischemia. Phosphorus-31 nuclear magnetic resonance studies of porcine myocardium in vivo.

  1990cites this paper
• Comparative 13C and 31P NMR assessment of altered metabolism during graded reductions in coronary flow in intact rat hearts.

  1989cites this paper
• Reduced aerobic metabolic efficiency in globally "stunned" myocardium.

  1989cites this paper
• Cellular mechanism of the modulation of contractile function by coronary perfusion pressure in ferret hearts.

  1989cites this paper
• Response of Myocardial Metabolites to Graded Regional Ischemia: 31P NMR Spectroscopy of Porcine Myocardium In Vivo

  1989cites this paper