Effects of Hypericum perforatum (St. John’s wort) on Passive Avoidance in the Rat: Evaluation of Potential Neurochemical Mechanisms Underlying its Antidepressant Activity

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Pharmacopsychiatry

• Publication date

  2001-06-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1055/s-2001-15449PMID 11518084
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Different pharmacokinetic and pharmacological effects following acute and chronic treatment with imipramine

  2005cited by this paper
• Multiple 5-HT Receptors in Passive Avoidance: Comparative Studies of p-Chloroamphetamine and 8-OH-DPAT

  2000cited by this paper
• Efficacy of an Hypericum Perforatum (St. John's Wort) Extract in Preventing and Reverting a Condition of Escape Deficit in Rats

  1999cited by this paper
• Enhancement of the serotonin-mediated acetylcholine release by repeated desmethylimipramine treatment in the hippocampus of freely moving rats.

  1999cited by this paper
• St. John's wort for depression: a meta-analysis of well-defined clinical trials.

  1999cited by this paper
• Comparison of hypericum extracts with imipramine and fluoxetine in animal models of depression and alcoholism.

  1999cited by this paper
• Hyperforin enhances the extracellular concentrations of catecholamines, serotonin and glutamate in the rat locus coeruleus.

  1999cited by this paper
• Hyperforin, a major antidepressant constituent of St. John's Wort, inhibits serotonin uptake by elevating free intracellular Na+1.

  1999cited by this paper
• Coupling efficiency of brain β-adrenergic receptors to Gs protein in suicide, alcoholism and control subjects

  1999cited by this paper
• Hypericum for depression. An update of the clinical evidence.

  1999cited by this paper
• Hyperforin represents the neurotransmitter reuptake inhibiting constituent of hypericum extract.

  1998cited by this paper
• Hyperforin as a possible antidepressant component of hypericum extracts.

  1998cited by this paper
• Basic psychopharmacology of antidepressants, part 1: Antidepressants have seven distinct mechanisms of action.

  1998cited by this paper
• Monoamine dysfunction and the pathophysiology and treatment of depression.

  1998cited by this paper
• Activity profiles of two hyperforin-containing hypericum extracts in behavioral models.

  1998cited by this paper
• Treatment of depression--newer pharmacotherapies.

  1998cited by this paper
• In vivo chronoamperometric measures of extracellular serotonin clearance in rat dorsal hippocampus: contribution of serotonin and norepinephrine transporters.

  1998cited by this paper
• Solubilized hypericin and pseudohypericin from Hypericum perforatum exert antidepressant activity in the forced swimming test.

  1998cited by this paper
• Psychopharmacology: The Fourth Generation of Progress

  1998cited by this paper
• Effects of Antidepressant Treatment on Inhibitory Avoidance Behavior and Amygdaloid β-Adrenoceptors in Rats

  1998cited by this paper
• Selective serotonin reuptake inhibitors in affective disorders — I. Basic pharmacology

  1998cited by this paper
• Subsensitivity of adenylyl cyclase-coupled receptors on mononuclear leukocytes from drug-free inpatients with a major depressive episode.

  1997cited by this paper
• Biologically Active and Other Chemical Constituents of the Herb of Hypericum perforatum L.

  1997cited by this paper
• Emotional memory and psychopathology.

  1997cited by this paper
• Effects of hypericum extract (LI 160) in biochemical models of antidepressant activity.

  1997cited by this paper
• In Vitro Receptor Binding and Enzyme Inhibition by Hypericum perforatum Extract

  1997cited by this paper
• Effects of the total extract and fractions of Hypericum perforatum in animal assays for antidepressant activity.

  1997cited by this paper
• Carrier‐dependent and Ca2+‐dependent 5‐HT and dopamine release induced by (+)‐amphetamine, 3,4‐methylendioxy‐methamphetamine, p‐chloroamphetamine and (+)‐fenfluramine

  1997cited by this paper
• Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structures.

  1997cited by this paper
• Analysis of mnemonic processing by means of totally reversible neural inactivations.

  1997cited by this paper
• In vivo effects of the simultaneous blockade of serotonin and norepinephrine transporters on serotonergic function. Microdialysis studies.

  1996cited by this paper
• The amygdala and emotion.

  1996cited by this paper
• Influence of separate and combined septal and amygdala lesions on memory, acoustic startle, anxiety, and locomotor activity in rats.

  1995cited by this paper
• Permeation properties of neurotransmitter transporters.

  1994cited by this paper
• Mammalian brain substrates of aversive classical conditioning.

  1993cited by this paper
• Neuroanatomical differences in the rate of beta-adrenergic receptor adaptation after repeated treatment with imipramine.

  1993cited by this paper
• The Adrenergic-Cholinergic Imbalance Hypothesis of Depression: A Review and a Perspective

  1993cited by this paper
• beta-adrenoceptors in brain and pineal from depressed suicide victims.

  1992cited by this paper
• A Comparative Study on Desipramine Pharmacokinetics in the Rat Brain after Administration of Desipramine or Imipramine

  1992cited by this paper
• Affinity modulation of [3H]imipramine, [3H]paroxetine and [3H]citalopram binding to the 5-HT transporter from brain and platelets.

  1991cited by this paper
• Preferential reduction of binding of 125I-iodopindolol to beta-1 adrenoceptors in the amygdala of rat after antidepressant treatments.

  1991cited by this paper
• Brain beta-adrenoceptor binding sites in antidepressant-free depressed suicide victims.

  1990cited by this paper
• Concurrent muscarinic and β-adrenergic blockade in rats impairs place-learning in a water maze and retention of inhibitory avoidance

  1990cited by this paper
• Selective activation of 5HT1A receptors induces lower lip retraction in the rat.

  1989cited by this paper
• Regionally selective increases in β-adrenergic receptor density in the brains of suicide victims

  1988cited by this paper
• [Animal experiments on the psychotropic action of a Hypericum extract].

  1987cited by this paper
• Biological markers in depression.

  1986cited by this paper
• Neurochemical and neuroendocrine dysregulation in affective disorders.

  1986cited by this paper
• Central serotonin neurones in avoidance learning: interactions with noradrenaline and dopamine neurones.

  1985cited by this paper
• Evidence for a role of brain serotonergic neurotransmission in avoidance learning.

  1985cited by this paper
• Inhibition of monoamine oxidase by hypericin.

  1984cited by this paper
• Muscarinic binding in suicides.

  1984cited by this paper
• The route of administration of imipramine as a factor affecting formation of its metabolite desipramine

  1982cited by this paper
• Human brain receptor alterations in suicide victims.

  1982cited by this paper
• Cerebral pharmacokinetics of imipramine in rats after single and multiple dosages

  1981cited by this paper
• Antidepressants and the muscarinic acetylcholine receptor.

  1977cited by this paper
• Memory formation: evidence for a specific neurochemical system in the amygdala.

  1977cited by this paper
• Development of beta-adrenergic receptor subsensitivity by antidepressants.

  1977cited by this paper
• Tricyclic antidepressants as antimuscarinic drugs: in vivo and in vitro studies.

  1977cited by this paper
• An animal behavior model for studying central serotonergic synapses.

  1976cited by this paper
• Behavioral evidence for the rapid release of CNS serotonin by PCA and fenfluramine.

  1976cited by this paper
• STUDIES IN VIVO ON THE RELATIONSHIP BETWEEN BRAIN TRYPTOPHAN, BRAIN 5‐HT SYNTHESIS AND HYPERACTIVITY IN RATS TREATED WITH A MONOAMINE OXIDASE INHIBITOR AND L‐TRYPTOPHAN

  1971cited by this paper
• Experimental Design: Procedures for the Behavioral Sciences

  1969cited by this paper
• The Biochemistry of Affective Disorders

  1967cited by this paper

• Perspectives on Animal Experimentation in Herbal Medicine Research: Ethical Dilemmas and Scientific Progress

  2024cites this paper
• Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis

  2016cites this paper
• Nature cures nature: Hypericum perforatum attenuates physical withdrawal signs in opium dependent rats

  2014cites this paper
• St. John's Wort increases brain serotonin synthesis by inhibiting hepatic tryptophan 2, 3 dioxygenase activity and its gene expression in stressed rats.

  2014cites this paper
• SEROTONIN IN EMOTIONAL MEMORY PROCESSES: NEUROPHARMACOLOGICAL STUDIES WITH EMPHASIS ON DEPRESSION

  2012cites this paper
• Effects of Hypericum perforatum extract on diabetes‐induced learning and memory impairment in rats

  2011cites this paper
• Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration

  2011cites this paper
• St. John's Wort modulates brain regional serotonin metabolism in swim stressed rats.

  2009cites this paper
• Adulterant profile of illicit street heroin and reduction of its precipitated physical dependence withdrawal syndrome by extracts of St John's wort (Hypericum perforatum)

  2009cites this paper
• EFEITO DO HYPERICUM PERFORATUM, EM PREPARAÇÃO HOMEOPÁTICA E FITOTERÁPICA, SOBRE O DESAMPARO APRENDIDO EM RATOS

  2006cites this paper
• Effects on transmitter uptake and their cellular and molecular basis

  2005cites this paper
• Biological Activity of Quinones

  2005cites this paper
• Neural monoaminergic mediation of the effect of St. John’s wort extract on prepulse inhibition of the acoustic startle response in rats

  2005cites this paper
• Hyperforin activates nonselective cation channels (NSCCs)

  2005cites this paper
• Modulation of neurotransmitter release and metabolism

  2005cites this paper
• Pharmacological and neurochemical evidence for antidepressant-like effects of the herbal product Catuama.

  2004cites this paper
• Hypericum perforatum L (St John's wort) preferentially increases extracellular dopamine levels in the rat prefrontal cortex

  2004cites this paper
• Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders

  2003cites this paper
• Current St John's wort research from mode of action to clinical efficacy.

  2003cites this paper
• Long term administration of Hypericum perforatum improves spatial learning and memory in the water maze.

  2002cites this paper