STUbL-mediated degradation of the transcription factor MATα2 requires degradation elements that coincide with corepressor binding sites

The yeast cell type regulator MATα (α2) is degraded through two ubiquitylation pathways, one of which has been minimally characterized. We identify two regions in α2 important for this pathway and show that these regions overlap specific binding sites for α2 corepressors, suggesting that α2 degradation is coordinated with its functional status.

• Publication year

  2015

• Venue

  Molecular Biology of the Cell

• Publication date

  2015-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E15-06-0436PMID 26246605PMCID 4591686
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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