Directed engineering of umbilical cord blood stem cells to produce C‐peptide and insulin

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Cell Proliferation

• Publication date

  2007-06-01

• Fields of study

  Biology, Medicine, Engineering

• Identifiers
  DOI 10.1111/j.1365-2184.2007.00439.xPMID 17531081PMCID PMC6496474
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2009influential citation
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  2009cites this paper
• [Increasing clinical applications of stem cells from umbilical cord blood and consequences for the handling of this biomaterial].

  2009cites this paper
• Autologous umbilical cord blood infusion for type 1 diabetes.

  2008cites this paper
• Critical issues for engineering cord blood stem cells to produce insulin

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  2008cites this paper
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  2008cites this paper
• [Cord blood banks].

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