Vagal reflexes following an exercise stress test: a simple clinical tool for gene-specific risk stratification in the long QT syndrome.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of the American College of Cardiology

• Publication date

  2012-12-18

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jacc.2012.08.1009PMID 23158531PMCID PMC3522767
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Long-QT syndrome: from genetics to management.

  2012cited by this paper
• Derivation and Validation of a Simple Exercise-Based Algorithm for Prediction of Genetic Testing in Relatives of LQTS Probands

  2011cited by this paper
• Sudden cardiac death, founder populations, and mushrooms: what is the link with gold mines and modifier genes?

  2011cited by this paper
• QTc behavior during exercise and genetic testing for the long-QT syndrome.

  2011cited by this paper
• Polymorphisms in the NOS1AP gene modulate QT interval duration and risk of arrhythmias in the long QT syndrome.

  2010cited by this paper
• The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome.

  2010cited by this paper
• Prevalence of the Congenital Long-QT Syndrome

  2009cited by this paper
• Incidence and Risk Factors of Arrhythmic Events in Catecholaminergic Polymorphic Ventricular Tachycardia

  2009cited by this paper
• NOS1AP Is a Genetic Modifier of the Long-QT Syndrome

  2009cited by this paper
• Long QT syndrome, a purely electrical disease? Not anymore

  2009cited by this paper
• Neural control of heart rate is an arrhythmia risk modifier in long QT syndrome.

  2008influential reference
• Left ventricular mechanical dispersion by tissue Doppler imaging: a novel approach for identifying high-risk individuals with long QT syndrome

  2008cited by this paper
• Long QT syndrome, a purely electrical disease? Not anymore.

  2008cited by this paper
• Effect of endurance exercise training on heart rate onset and heart rate recovery responses to submaximal exercise in animals susceptible to ventricular fibrillation.

  2007cited by this paper
• The Common Long-QT Syndrome Mutation KCNQ1/A341V Causes Unusually Severe Clinical Manifestations in Patients With Different Ethnic Backgrounds: Toward a Mutation-Specific Risk Stratification

  2007cited by this paper
• Clinical Aspects of Type-1 Long-QT Syndrome by Location, Coding Type, and Biophysical Function of Mutations Involving the KCNQ1 Gene

  2007cited by this paper
• Subunit Interaction Determines IKs Participation in Cardiac Repolarization and Repolarization Reserve

  2005cited by this paper
• Autonomic Control of Cardiac Action Potentials: Role of Potassium Channel Kinetics in Response to Sympathetic Stimulation

  2005cited by this paper
• KCNH2-K897T Is a Genetic Modifier of Latent Congenital Long-QT Syndrome

  2005cited by this paper
• Management of long QT syndrome

  2005cited by this paper
• Phenotypic Variability and Unusual Clinical Severity of Congenital Long-QT Syndrome in a Founder Population

  2005cited by this paper
• Heart rate recovery after exercise: a predictor of ventricular fibrillation susceptibility after myocardial infarction.

  2005cited by this paper
• Compound Mutations: A Common Cause of Severe Long-QT Syndrome

  2004cited by this paper
• Risk stratification in the long-QT syndrome.

  2003cited by this paper
• Risk stratification in the long-QT syndrome.

  2003cited by this paper
• How Really Rare Are Rare Diseases?:

  2003cited by this paper
• Exercise-Induced Increase in Baroreflex Sensitivity Predicts Improved Prognosis After Myocardial Infarction

  2002cited by this paper
• Genetic Influences on Baroreflex Function in Normal Twins

  2001cited by this paper
• Baroreflex Sensitivity

  1999influential reference
• Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction

  1998cited by this paper
• Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators.

  1998cited by this paper
• Erratum: Long QT syndrome patients with mutations on the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate: Implications for gene-specific therapy (Circulation (1995) 92 (3381-3386))

  1996cited by this paper
• Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.

  1995cited by this paper
• Quantitative analysis of T wave abnormalities and their prognostic implications in the idiopathic long QT syndrome.

  1994cited by this paper
• Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure.

  1994cited by this paper
• Vagal Control of the Heart: Experimental Basis and Clinical Implications

  1994cited by this paper
• Unsuspected Echocardiographic Abnormality in the Long QT Syndrome: Diagnostic, Prognostic, and Pathogenetic Implications

  1991cited by this paper
• Cardiac Electrophysiology: From Cell to Bedside

  1990cited by this paper
• Idiopathic long QT syndrome: progress and questions.

  1985cited by this paper
• The effects of daily exercise on susceptibility to sudden cardiac death.

  1984cited by this paper
• The long Q-T syndrome.

  1975cited by this paper
• Electrical alternation of the T-wave: clinical and experimental evidence of its relationship with the sympathetic nervous system and with the long Q-T syndrome.

  1975cited by this paper
• Life-threatening Arrhythmias Genotype-phenotype Correlation in the Long-qt Syndrome : Gene-specific Triggers for Genotype-phenotype Correlation in the Long-qt Syndrome Gene-specific Triggers for Life-threatening Arrhythmias

  year unknowninfluential reference
• Polymorphisms in the NOS 1 AP Gene Modulate QT Interval Duration and Risk of Arrhythmias in the Long QT Syndrome

  year unknowncited by this paper

• Characteristics of sudden cardiac arrest during endurance racing: a decade of the Paris registry

  2026cites this paper
• What Lies Beneath: Provoking the QT to Identify Risk in Long QT syndrome.

  2025cites this paper
• Neonatal death of siblings with Uhl’s disease and KCNH2 mutation - A rare association

  2024cites this paper
• From genes to clinical management: A comprehensive review of long QT syndrome pathogenesis and treatment

  2024cites this paper
• Novel risk predictor of arrhythmias for patients with potassium channel related congenital Long-QT Syndrome.

  2024cites this paper
• Roles of exercise treadmill test in the diagnosis & risk stratification of cardiac channelopathies

  2023cites this paper
• Holter Recordings at Initial Assessment for Long QT Syndrome: Relationship to Genotype Status and Cardiac Events

  2022cites this paper
• Exercise in the Genetic Arrhythmia Syndromes - A Review.

  2022cites this paper
• An inherited sudden cardiac arrest syndrome may be based on primary myocardial and autonomic nervous system abnormalities.

  2021cites this paper
• Autonomic cardiac innervation: impact on the evolution of arrhythmias in inherited cardiac arrhythmia syndromes

  2021cites this paper
• Fear of Sudden Death During Sport Activity and the Long QT Syndrome

  2021cites this paper
• Aberrant autonomic pattern during the post-exercise recovery phase in long QT syndrome patients.

  2021cites this paper
• Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

  2020cites this paper
• Neuroscience in the heart: recent advances in neurocardiac communication and its role in cardiac arrhythmias.

  2020cites this paper
• Heritable arrhythmias associated with abnormal function of cardiac potassium channels.

  2020cites this paper
• Specific Cardiovascular Diseases and Competitive Sports Participation: Channelopathies

  2020cites this paper
• Recurrent dramatic QT prolongation in a patient with the sickle cell disease

  2020cites this paper
• Frequency Domain Heart Period and QT Interval Variability Markers Are Linked to Arrhythmic Risk in Long QT Syndrome Type 2

  2020cites this paper
• Inherited cardiac arrhythmias

  2020cites this paper
• Autonomic Control of the Heart and Its Clinical Impact. A Personal Perspective

  2020cites this paper
• Genetic Determinants Affecting the Relationship Between the Autonomic Nervous System and Sudden Death

  2020cites this paper
• Dynamic QT response to cold‐water face immersion in long‐QT syndrome type 3

  2020cites this paper
• Exercise-Related Acute Cardiovascular Events and Potential Deleterious Adaptations Following Long-Term Exercise Training: Placing the Risks Into Perspective–An Update: A Scientific Statement From the American Heart Association

  2020cites this paper
• Proarrhythmic proclivity of left-stellate ganglion stimulation in a canine model of drug-induced long-QT syndrome type 1.

  2019cites this paper
• The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies

  2019cites this paper
• The Brain-Heart Connection in Sympathetically Triggered Inherited Arrhythmia Syndromes.

  2019cites this paper
• Long and Short QT Syndromes

  2018cites this paper
• Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort

  2017cites this paper
• Lidocaine attenuation testing: An in vivo investigation of putative LQT3-associated variants in the SCN5A-encoded sodium channel.

  2017cites this paper
• Channelopathies as Causes of Sudden Cardiac Death.

  2017cites this paper
• Long-term aerobic exercise in Calsequestrin2 knockout mice accentuates vagal antagonism during β-adrenergic stimulation which restricts heart rate acceleration and paradoxically increases abnormal ryanodine receptor calcium leak in ventricular myocytes

  2017cites this paper
• Accentuated vagal antagonism paradoxically increases ryanodine receptor calcium leak in long-term exercised Calsequestrin2 knockout mice.

  2017cites this paper
• The electrophysiological development of cardiomyocytes.

  2016cites this paper
• The role of hereditary KCNQ1 mutations in water-related death

  2016cites this paper
• QT Dynamics During Exercise in Asymptomatic Children with Long QT Syndrome Type 3

  2016cites this paper
• Are There Deleterious Cardiac Effects of Acute and Chronic Endurance Exercise?

  2016cites this paper
• Autonomic control of heart rate and QT interval variability influences arrhythmic risk in long QT syndrome type 1.

  2015influential citation
• Long- und Short-QT-Syndrome

  2015cites this paper
• Breath Holding Spells in Children with Long QT Syndrome.

  2015cites this paper
• A Refined Multiscale Self-Entropy Approach for the Assessment of Cardiac Control Complexity: Application to Long QT Syndrome Type 1 Patients

  2015cites this paper
• Complex excitation dynamics underlie polymorphic ventricular tachycardia in a transgenic rabbit model of long QT syndrome type 1.

  2015cites this paper
• The Year in Cardiology 2013: arrhythmias.

  2014cites this paper
• Multiscale Complexity Analysis of the Cardiac Control Identifies Asymptomatic and Symptomatic Patients in Long QT Syndrome Type 1

  2014cites this paper
• Risk stratification for sudden cardiac death: current status and challenges for the future

  2014cites this paper
• Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target?

  2014cites this paper
• Sudden death by stress: how far under the nerves should we dig to find out why LQT1 patients die?

  2014cites this paper
• Épreuves d’effort chez l’enfant

  2014cites this paper
• Genetic Variants and Risk in Sudden Cardiac Death Syndromes

  2014cites this paper
• 93 – Long and Short QT Syndromes

  2014cites this paper
• Filtering approach based on empirical mode decomposition improves the assessment of short scale complexity in long QT syndrome type 1 population

  2014cites this paper
• Low-Pass Filtering Approach via Empirical Mode Decomposition Improves Short-Scale Entropy-Based Complexity Estimation of QT Interval Variability in Long QT Syndrome Type 1 Patients

  2014cites this paper
• Mechanistic Basis for Atrial and Ventricular Arrhythmias Caused by KCNQ1 Mutations

  2013cites this paper
• The long QT syndrome: a transatlantic clinical approach to diagnosis and therapy.

  2013cites this paper
• Practical issues in the management of the long QT syndrome: focus on diagnosis and therapy.

  2013cites this paper
• A review of JACC articles on the topic of heart rhythm disorders: 2011-2012.

  2013cites this paper
• Exercise and vagal reflex in long QT syndrome type 1.

  2012influential citation
• Congenital long QT syndrome: Diagnosis

  year unknowncites this paper