Mitochondrial quinone reductases: complex I.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Methods in Enzymology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0076-6879(04)82001-9PMID 15047093
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging.

  2002cited by this paper
• The energy-transducing NADH: quinone oxidoreductase, complex I.

  2002cited by this paper
• Mitochondrial superoxide anion production and release into intermembrane space.

  2002cited by this paper
• The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron–sulfur cluster N2

  2001cited by this paper
• Introduction: Complex I—An L-Shaped Black Box

  2001cited by this paper
• GRIM-19, a Cell Death Regulatory Gene Product, Is a Subunit of Bovine Mitochondrial NADH:Ubiquinone Oxidoreductase (Complex I)*

  2001cited by this paper
• Isolated complex I deficiency in children: Clinical, biochemical and genetic aspects

  2000cited by this paper
• Catalytic Activities of Mitochondrial ATP Synthase in Patients with Mitochondrial DNA T8993G Mutation in the ATPase 6 Gene Encoding Subunit a *

  2000cited by this paper
• Mitochondrial bioenergetics in aging.

  2000cited by this paper
• Structure of the respiratory NADH:ubiquinone oxidoreductase (complex I)

  1999cited by this paper
• Biochemical features of mtDNA 14484 (ND6/m64V) point mutation associated with Leber's hereditary optic neuropathy

  1999cited by this paper
• Quinone specificity of complex I.

  1998cited by this paper
• Catalytic properties of the mitochondrial NADH-ubiquinone oxidoreductase (complex I) and the pseudo-reversible active/inactive enzyme transition.

  1998cited by this paper
• Inhibitors of NADH-ubiquinone reductase: an overview.

  1998cited by this paper
• Inhibitors of NADH-ubiquinone reductase: an overview.

  1998cited by this paper
• Human complex I defects in neurodegenerative diseases.

  1998cited by this paper
• Mitochondrial Complex I defects in aging

  1997cited by this paper
• Proton Pumping of Mitochondrial Complex I: Differential Activation by Analogs of Ubiquinone

  1997cited by this paper
• Protonophoric activity of NADH coenzyme Q reductase and ATP synthase in coupled submitochondrial particles from horse platelets.

  1997cited by this paper
• The specificity of mitochondrial complex I for ubiquinones.

  1996cited by this paper
• Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines.

  1996cited by this paper
• Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles.

  1996cited by this paper
• Inhibitor sensitivity of respiratory complex I in human platelets: A possible biomarker of ageing

  1996cited by this paper
• Threshold Effects and Control of Oxidative Phosphorylation in Nonsynaptic Rat Brain Mitochondria

  1996cited by this paper
• Leigh syndrome: Clinical features and biochemical and DNA abnormalities

  1996cited by this paper
• Underevaluation of complex I activity by the direct assay of NADH‐coenzyme Q reductase in rat liver mitochondria

  1995cited by this paper
• The proton‐pumping respiratory complex I of bacteria and mitochondria and its homologue in chloroplasts

  1995cited by this paper
• Major changes in complex I activity in mitochondria from aged rats may not be detected by direct assay of NADH:coenzyme Q reductase.

  1995cited by this paper
• Functional molecular aspects of the NADH dehydrogenases of plant mitochondria

  1995cited by this paper
• Natural substances (acetogenins) from the family Annonaceae are powerful inhibitors of mitochondrial NADH dehydrogenase (Complex I).

  1994cited by this paper
• Functional alterations of the mitochondrially encoded ND4 subunit associated with Leber's hereditary optic neuropathy

  1994cited by this paper
• Control of oxidative phosphorylation in rat muscle mitochondria: implications for mitochondrial myopathies.

  1993cited by this paper
• Steady-state kinetics of ubiquinol-cytochrome c reductase in bovine heart submitochondrial particles: diffusional effects.

  1993cited by this paper
• Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase

  1993cited by this paper
• Complex I and complex III of mitochondria have common inhibitors acting as ubiquinone antagonists.

  1993cited by this paper
• Kinetic characterization of the ATP-dependent proton pump in bacterial photosynthetic membranes : a study with the fluorescent probe 9-amino-6-chloro-2-methoxyacridine

  1993cited by this paper
• The effect of ΔμH+ on the interaction of rotenone with Complex I of submitochondrial particles

  1992cited by this paper
• The effect of delta mu H+ on the interaction of rotenone with complex I of submitochondrial particles.

  1992cited by this paper
• Redox-linked proton translocation by NADH-ubiquinone reductase (complex I)

  1991cited by this paper
• Measurements of transmembrane pH differences of low extents in bacterial chromatophores

  1991cited by this paper
• Inhibition by capsaicin of NADH-quinone oxidoreductases is correlated with the presence of energy-coupling site 1 in various organisms.

  1990cited by this paper
• Direct and respiratory chain-mediated redox cycling of adrenochrome.

  1990cited by this paper
• Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio.

  1988cited by this paper
• Structure of NADH-Ubiquinone Reductase (Complex I)

  1987cited by this paper
• Mucidin and strobilurin A are identical and inhibit electron transfer in the cytochrome bc1 complex of the mitochondrial respiratory chain at the same site as myxothiazol.

  1986cited by this paper
• On the mechanism of inhibition of NADH oxidase by ubiquinone-3

  1984cited by this paper
• Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria.

  1984cited by this paper
• Two protons are pumped from the mitochondrial matrix per electron transferred between NADH and ubiquinone

  1984cited by this paper
• Activation of site I redox-driven H+ pump by exogenous quinones in intact mitochondria.

  1982cited by this paper
• Quantification of the contribution of various steps to the control of mitochondrial respiration.

  1982cited by this paper
• Immunological assays of the NADH dehydrogenase content of bovine heart mitochondria and submitochondrial particles

  1980cited by this paper
• Analytical and preparative high-performance liquid chromatography separation of flavin and flavin analog coenzymes.

  1980cited by this paper
• Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria.

  1980cited by this paper
• MOlecular democracy: who shares the controls?

  1979cited by this paper
• Stabilization of mitochondrial functions with digitonin.

  1979cited by this paper
• Hydroperoxide metabolism in mammalian organs.

  1979cited by this paper
• [14] Stabilization of mitochondrial functions with digitonin

  1979cited by this paper
• Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria.

  1977cited by this paper
• Carboxins: powerful selective inhibitors of succinate oxidation in animal tissues.

  1976cited by this paper
• The inhibition of NADH oxidase by the lower homologs of coenzyme Q.

  1975cited by this paper
• The use of acetylated ferricytochrome c for the detection of superoxide radicals produced in biological membranes.

  1975cited by this paper
• [134] Simultaneous microdetermination of riboflavin, FMN, and FAD in animal tissues

  1971cited by this paper
• Studies of the energy-transfer system of submitochondrial particles. 2. Effects of oligomycin and aurovertin.

  1968cited by this paper
• [81] The isolation, properties, and assay of ATP synthetase II

  1967cited by this paper
• [13] Preparation, properties, and conditions for assay of mitochondria: Slaughterhouse material, small-scale

  1967cited by this paper
• [8] Application of inhibitors and uncouplers for a study of oxidative phosphorylation

  1967cited by this paper
• [33] Preparation and assay of phosphorylating submitochondrial particles: Particles from rat liver prepared by drastic sonication

  1967cited by this paper
• STUDIES ON THE RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE. VI. FURTHER PURIFICATION AND PROPERTIES OF THE ENZYME FROM BEEF HEART.

  1964cited by this paper
• Studies on the mechanism of oxidative phosphorylation: VII. Preparation of a submitochondrial particle (ETPH) which is capable of fully coupled oxidative phosphorylation

  1964cited by this paper
• Studies on the electron transfer system. XL. Preparation and properties of mitochondrial DPNH-coenzyme Q reductase.

  1962cited by this paper
• The respiratory chain and oxidative phosphorylation.

  1956cited by this paper

• Advancements in synthetic methodologies and biological applications of lawsone derivatives.

  2025cites this paper
• New 2-Acetyl-3-aminophenyl-1,4-naphthoquinones: Synthesis and In Vitro Antiproliferative Activities on Breast and Prostate Human Cancer Cells

  2020cites this paper
• Multiparametric analysis of the effectiveness of cisplatin on cutaneous squamous carcinoma cells using two different types of adjuvants

  2020cites this paper
• Metformin Alters Locomotor and Cognitive Function and Brain Metabolism in Normoglycemic Mice

  2019cites this paper
• Pharmacology of ME‐344, a novel cytotoxic isoflavone

  2019cites this paper
• Resveratrol preserves mitochondrial function in a human post-mitotic cell model.

  2018cites this paper
• Antioxidant and Antifungal Activity of Naphthoquinones Dimeric Derived from Lawsone

  2017cites this paper
• An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition

  2017cites this paper
• Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia

  2017cites this paper
• MASTERARBEIT / MASTER’S THESIS

  2016cites this paper
• Contribution to the study of mouse liver chemical carcinogenesis

  2016cites this paper
• to rat exposure to 60 or 85% oxygen Differential responses of targeted lung redox enzymes

  2015cites this paper
• Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries.

  2015cites this paper
• Use of Ultrasound and Microwave Irradiation for Clean and Efficient Synthesis of 3,3'-(Arylmethylene)bis (2-hydroxynaphthalene-1,4-dione) Derivatives

  2014cites this paper
• Synthesis and biological evaluation of novel ferrocene-naphthoquinones as antiplasmodial agents.

  2013cites this paper
• Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential

  2013cites this paper
• Antimalarial activity of nepodin isolated from Rumex crispus

  2013cites this paper
• Mitochondrial and liver oxidative stress alterations induced by N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine: relevance for hepatotoxicity

  2013cites this paper
• Histology, bioenergetics and oxidative stress in mouse liver exposed to N-diethylnitrosamine.

  2012cites this paper
• Development of an Assay for Complex I/Complex III of the Respiratory Chain Using Solid Supported Membranes and Its Application in Mitochondrial Toxicity Screening in Drug Discovery

  2011cites this paper
• Quantitative Evaluation of Redox Processes in Intact Rat Lungs and Endothelial Cells and the Effect of Hyperoxia

  2011cites this paper
• Alternative Mitochondrial Electron Transfer as a Novel Strategy for Neuroprotection*

  2011cites this paper
• Differential responses of targeted lung redox enzymes to rat exposure to 60 or 85% oxygen.

  2011cites this paper
• HPLC Method for the Simultaneous Determination of Ten Annonaceous Acetogenins after Supercritical Fluid CO2 Extraction

  2010cites this paper
• Kinetics and regulation of mammalian NADH-ubiquinone oxidoreductase (Complex I).

  2010cites this paper
• Methylene Blue Provides Behavioral and Metabolic Neuroprotection Against Optic Neuropathy

  2009cites this paper
• Comparison of two methods for assaying complex I activity in mitochondria isolated from rat liver, brain and heart.

  2009influential citation
• Strategies of neuroprotection in an in vivo model of retinal degeneration induced by mitochondrial dysfunction

  2009cites this paper
• Mitochondrial Decay in the Brains of Old Rats: Ameliorating Effect of Alpha-Lipoic Acid and Acetyl-l-carnitine

  2009influential citation
• Disruption of hepatic mitochondrial bioenergetics is not a primary mechanism for the toxicity of methoprene - relevance for toxicological assessment.

  2008cites this paper
• Coenzyme Q1 redox metabolism during passage through the rat pulmonary circulation and the effect of hyperoxia.

  2008cites this paper
• Data mining of NCI's anticancer screening database reveals mitochondrial complex I inhibitors cytotoxic to leukemia cell lines.

  2007cites this paper
• An Assembled Complex IV Maintains the Stability and Activity of Complex I in Mammalian Mitochondria*

  2007cites this paper
• Role of mitochondrial electron transport complex I in coenzyme Q1 reduction by intact pulmonary arterial endothelial cells and the effect of hyperoxia.

  2007cites this paper
• Effects of site-directed mutations in Escherichia coli succinate dehydrogenase on the enzyme activity and production of superoxide radicals.

  2006cites this paper
• Nuclear Suppression of Mitochondrial Defects in Cells without the ND6 Subunit

  2006cites this paper
• Functional Characterization and Target Validation of Alternative Complex I of Plasmodium falciparum Mitochondria

  2006cites this paper
• Acetogenins from Annonaceae: recent progress in isolation, synthesis and mechanisms of action.

  2005cites this paper
• Multiple ligand binding and kinetic isotope effects in methanol dehydrogenase

  2004cites this paper