Oxysterol-binding protein-related protein (ORP) 9 is a PDK-2 substrate and regulates Akt phosphorylation.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Cellular Signalling

• Publication date

  2007-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.CELLSIG.2006.07.009PMID 16962287
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nonvesicular sterol movement from plasma membrane to ER requires oxysterol-binding protein–related proteins and phosphoinositides

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• Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein.

  2006cited by this paper
• SHIP Down-Regulates FcεR1-Induced Degranulation at Supraoptimal IgE or Antigen Levels

  2005cited by this paper
• Structural mechanism for sterol sensing and transport by OSBP-related proteins

  2005cited by this paper
• PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.

  2005cited by this paper
• SHIP down-regulates FcepsilonR1-induced degranulation at supraoptimal IgE or antigen levels.

  2005cited by this paper
• OSBP Is a Cholesterol-Regulated Scaffolding Protein in Control of ERK1/2 Activation

  2005cited by this paper
• Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

  2005cited by this paper
• VAMP-associated protein-A regulates partitioning of oxysterol-binding protein-related protein-9 between the endoplasmic reticulum and Golgi apparatus.

  2004cited by this paper
• Structure, regulation and function of PKB/AKT--a major therapeutic target.

  2004cited by this paper
• FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

  2004cited by this paper
• Protein Kinase C βII Regulates Akt Phosphorylation on Ser-473 in a Cell Type- and Stimulus-specific Fashion*♦

  2004cited by this paper
• Oxysterol binding proteins: in more than one place at one time?

  2004cited by this paper
• In vivo role of the PIF‐binding docking site of PDK1 defined by knock‐in mutation

  2003cited by this paper
• Identification of novel ERK-mediated feedback phosphorylation sites at the C-terminus of B-Raf

  2003cited by this paper
• SHIP Negatively Regulates IgE + Antigen-Induced IL-6 Production in Mast Cells by Inhibiting NF-κB Activity1

  2002cited by this paper
• mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.

  2002cited by this paper
• Vesicle-associated Membrane Protein-associated Protein-A (VAP-A) Interacts with the Oxysterol-binding Protein to Modify Export from the Endoplasmic Reticulum*

  2002cited by this paper
• PKCβ modulates antigen receptor signaling via regulation of Btk membrane localization

  2001cited by this paper
• Novel Members of the Human Oxysterol-binding Protein Family Bind Phospholipids and Regulate Vesicle Transport*

  2001cited by this paper
• Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells.

  2001cited by this paper
• Studies of Different Aspects of the Role of Protein Kinase C in Mast Cells

  2001cited by this paper
• Inhibition of degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cbeta.

  2000cited by this paper
• Thapsigargin-Induced Degranulation of Mast Cells Is Dependent on Transient Activation of Phosphatidylinositol-3 Kinase1

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• Anchoring proteins for protein kinase C: a means for isozyme selectivity.

  1998cited by this paper
• Differential Effects of Sphingomyelin Hydrolysis and Cholesterol Transport on Oxysterol-binding Protein Phosphorylation and Golgi Localization*

  1998cited by this paper
• The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes.

  1998cited by this paper
• The specificity of association of the IgD molecule with the accessory proteins BAP31/BAP29 lies in the IgD transmembrane sequence.

  1996cited by this paper
• Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

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• Functional omics of ORP7 in primary endothelial cells

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• The emerging roles of OSBP-related proteins in cancer: Impacts through phosphoinositide metabolism and protein-protein interactions.

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• [Budding yeast, a model and a tool… also for biomedical research].

  2020cites this paper
• [A lipid exchange market : vectorial cholesterol transport by the protein OSBP].

  2020cites this paper
• Role of oxysterol-binding protein-related proteins in malignant human tumours.

  2020cites this paper
• Bis(monoacylglycero)phosphate regulates oxysterol binding protein-related protein 11 dependent sterol trafficking.

  2019cites this paper
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  2018cites this paper
• ORP2 - A Sterol Sensor Controlling Hepatocellular Bioenergetics and Actin Cytoskeletal Functions

  2018cites this paper
• Oxysterol, 5α-cholestan-3-one, modulates a contractile response to β2-adrenoceptor stimulation in the mouse atria: Involvement of NO signaling.

  2017cites this paper
• Structural insights into nonvesicular lipid transport by the oxysterol binding protein homologue family.

  2016cites this paper
• Aurora Kinase A expression predicts platinum-resistance and adverse outcome in high-grade serous ovarian carcinoma patients

  2016cites this paper
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  2016cites this paper
• OSBP-Related Protein Family: Mediators of Lipid Transport and Signaling at Membrane Contact Sites.

  2016cites this paper
• Molecular mechanisms of the anti-cancer action of schweinfurthins

  2015cites this paper
• OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity.

  2015cites this paper
• OSBP-Related Protein Family in Lipid Transport Over Membrane Contact Sites

  2015cites this paper
• Association of oxysterol binding protein-related protein 9 polymorphism with cerebral infarction in Hunan Han population

  2014cites this paper
• Characterization of the Sterol and Phosphatidylinositol 4-Phosphate Binding Properties of Golgi-Associated OSBP-Related Protein 9 (ORP9)

  2014cites this paper
• The study on oxysterol-binding protein (OSBP) and related protein 9 (ORP9) ligands: sterols and phosphatidylinositol 4-phosphate

  2014cites this paper
• 27-Hydroxycholesterol and 7alpha-hydroxycholesterol trigger a sequence of events leading to migration of CCR5-expressing Th1 lymphocytes.

  2014cites this paper
• Oxysterol binding protein homologues : Novel functions in intracellular transport and adipogenesis

  2013cites this paper
• The 1,4-benzodiazepine Ro5-4864 (4-chlorodiazepam) suppresses multiple pro-inflammatory mast cell effector functions

  2013cites this paper
• PtdIns(4)P signalling and recognition systems.

  2013cites this paper
• Structure of Osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins.

  2013cites this paper
• Modification of the lipidome in RAW264.7 macrophage subjected to stable silencing of oxysterol-binding proteins.

  2013cites this paper
• Oxysterol-binding proteins: sterol and phosphoinositide sensors coordinating transport, signaling and metabolism.

  2013cites this paper
• Modulating the Hedgehog pathway

  2013cites this paper
• Oxysterol-binding proteins: functions in cell regulation beyond lipid metabolism.

  2013cites this paper
• Oxysterols and Their Cellular Effectors

  2012cites this paper
• Oxysterol‐binding proteins–emerging roles in cell regulation

  2012cites this paper
• The effect of phosphorylation on oxysterol-binding protein (OSBP) sterol binding activity

  2012cites this paper
• Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis

  2012cites this paper
• Cytoplasmic oxysterol-binding proteins: sterol sensors or transporters?

  2011cites this paper
• Gene Expression Changes in Areas of Focal Loss of Retinal Ganglion Cells in the Retina of DBA / 2 J Mice

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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• Functional characterization of acyl-CoA binding protein (ACBP) and oxysterol binding protein-related proteins (ORPS) from Cryptosporidium parvum

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• Yeast oxysterol-binding proteins: sterol transporters or regulators of cell polarization?

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• Characteristics of oxysterol binding proteins.

  2008cites this paper
• Emerging roles of the oxysterol-binding protein family in metabolism, transport, and signaling

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• OSBP-related proteins: lipid sensors or transporters?

  2007cites this paper