Rapid intranasal delivery of chloramphenicol acetyltransferase in the active form to different brain regions as a model for enzyme therapy in the CNS.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Neuroscience Methods

• Publication date

  2016-02-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.jneumeth.2015.11.027PMID 26688469PMCID PMC4715996
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• MMP‐9 in translation: from molecule to brain physiology, pathology, and therapy

  2016cited by this paper
• Rapid Transport within Cerebral Perivascular Spaces Underlies Widespread Tracer Distribution in the Brain after Intranasal Administration

  2015cited by this paper
• The nasal approach to delivering treatment for brain diseases: an anatomic, physiologic, and delivery technology overview.

  2014cited by this paper
• Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro

  2014cited by this paper
• Intranasal insulin to treat and protect against posttraumatic stress disorder.

  2013influential reference
• Intranasal delivery of biologics to the central nervous system.

  2012influential reference
• Intranasal Treatment of Central Nervous System Dysfunction in Humans

  2012cited by this paper
• Lysosomal enzyme can bypass the blood-brain barrier and reach the CNS following intranasal administration.

  2012cited by this paper
• A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

  2012cited by this paper
• Intranasal nerve growth factor enhances striatal neurogenesis in adult rats with focal cerebral ischemia

  2011cited by this paper
• Delivery of interferon-beta to the monkey nervous system following intranasal administration.

  2008cited by this paper
• Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration.

  2004cited by this paper
• Nasal drug delivery--possibilities, problems and solutions.

  2003cited by this paper
• Permeability issues in nasal drug delivery.

  2002cited by this paper
• Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis.

  2001cited by this paper
• Delivery of Neurotrophic Factors to the Central Nervous System

  2001cited by this paper
• Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage.

  2001cited by this paper
• Quantitative analysis of the olfactory pathway for drug delivery to the brain.

  1995cited by this paper
• Tubule formation by human surface respiratory epithelial cells cultured in a three-dimensional collagen lattice.

  1993cited by this paper
• Brain Maps: Structure of the Rat Brain

  1992cited by this paper
• A method for increasing the sensitivity of chloramphenicol acetyltransferase assays in extracts of transfected cultured cells.

  1987cited by this paper
• Inducible expression of a cloned heat shock fusion gene in sea urchin embryos.

  1984cited by this paper
• Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

  1982cited by this paper

• Intranasal delivery of drug-loaded polymeric nanomicelles for brain targeting: a comprehensive review

  2025cites this paper
• Exploring the Potential of Nasal Drug Delivery for Brain Targeted Therapy: A Detailed Analysis

  2024cites this paper
• Research progress in brain-targeted nasal drug delivery

  2024cites this paper
• Can Amphotericin B-mediated effects be limited using intranasal versus intravenous route?

  2023cites this paper
• Nasal Drug Delivery System for Brain Targeting: A Potential Route

  2022cites this paper
• Evaluation of Recent Intranasal Drug Delivery Systems to the Central Nervous System

  2022cites this paper
• Recent progress in nanocarriers for direct nose to brain drug delivery

  2021cites this paper
• TARGETABLE MULTI-DRUG NANOPARTICLES FOR TREATMENT OF GLIOBLASTOMA WITH NEUROIMAGING ASSESSMENT

  2020cites this paper
• Imaging of intranasal drug delivery to the brain.

  2020cites this paper
• A OVERVIEW OF NASAL TO BRAIN DRUG DELIVERY

  2020cites this paper
• Review Imaging of intranasal drug delivery to the brain

  2020cites this paper
• Cut off Your Nose to Spite Your Face: Face, Nose, The Paranasal Sinuses and Smell Related to Taste

  2018cites this paper
• Mixed cationic liposomes for brain delivery of drugs by the intranasal route: The acetylcholinesterase reactivator 2-PAM as encapsulated drug model.

  2018cites this paper
• Current Strategies for the Delivery of Therapeutic Proteins and Enzymes to Treat Brain Disorders.

  2017cites this paper
• Effect of administration method, animal weight and age on the intranasal delivery of drugs to the brain.

  2017cites this paper
• Intranasal delivery of N‐terminal modified leptin‐pluronic conjugate for treatment of obesity

  2017cites this paper
• Formulation and device design to increase nose to brain drug delivery

  2016cites this paper