Reciprocal modulation of phospholipase Cβ isoforms: Adaptation to chronic morphine

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2003-11-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.2335885100PMID 14597703PMCID PMC263874
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular mechanisms of drug addiction.

  2004cited by this paper
• Facilitative interactions between vasoactive intestinal polypeptide and receptor type-selective opioids: implications for sensory afferent regulation of spinal opioid action.

  2003cited by this paper
• Chronic morphine induces the concomitant phosphorylation and altered association of multiple signaling proteins: A novel mechanism for modulating cell signaling

  2001cited by this paper
• Coincident signalling between the Gi/Go‐coupled δ‐opioid receptor and the Gq‐coupled m3 muscarinic receptor at the level of intracellular free calcium in SH‐SY5Y cells

  2001cited by this paper
• Regulation of phosphoinositide-specific phospholipase C.

  2001cited by this paper
• Opioid tolerance and the emergence of new opioid receptor-coupled signaling

  2000cited by this paper
• Structure, function, and control of phosphoinositide-specific phospholipase C.

  2000cited by this paper
• Molecular Mechanism of the Inhibition of Phospholipase C β3 by Protein Kinase C*

  2000cited by this paper
• Molecular mechanism of the inhibition of phospholipase C beta 3 by protein kinase C.

  2000cited by this paper
• Genetic alteration of phospholipase C beta3 expression modulates behavioral and cellular responses to mu opioids.

  1999cited by this paper
• Involvement of phospholipid signal transduction pathways in morphine tolerance in mice

  1999cited by this paper
• Genetic alteration of phospholipase C β3 expression modulates behavioral and cellular responses to μ opioids

  1999cited by this paper
• Opioid withdrawal activates MAP kinase in locus coeruleus neurons in morphine‐dependent rats in vivo

  1998cited by this paper
• Chronic morphine augments adenylyl cyclase phosphorylation: relevance to altered signaling during tolerance/dependence.

  1998cited by this paper
• Chronic morphine augments G(beta)(gamma)/Gs(alpha) stimulation of adenylyl cyclase: relevance to opioid tolerance.

  1998cited by this paper
• delta Opioid receptor subtypes activate inositol-signaling pathways in the production of antinociception.

  1998cited by this paper
• Differential effect of chronic morphine on mRNA encoding adenylyl cyclase isoforms: relevance to physiological sequela of tolerance/dependence.

  1998cited by this paper
• TGF-beta signal transduction.

  1998cited by this paper
• Signaling through scaffold, anchoring, and adaptor proteins.

  1997cited by this paper
• G-protein betagamma subunits antagonize protein kinase C-dependent phosphorylation and inhibition of phospholipase C-beta1.

  1997cited by this paper
• Altered μ‐Opiate Receptor‐G Protein Signal Transduction Following Chronic Morphine Exposure

  1997cited by this paper
• Role of Phospholipase C (cid:98) 3 Phosphorylation in the Desensitization of Cellular Responses to Platelet-activating Factor*

  1997cited by this paper
• CREB (cAMP Response Element-Binding Protein) in the Locus Coeruleus: Biochemical, Physiological, and Behavioral Evidence for a Role in Opiate Dependence

  1997cited by this paper
• Role of phospholipase Cbeta3 phosphorylation in the desensitization of cellular responses to platelet-activating factor.

  1997cited by this paper
• δ‐Opioids Stimulate Inositol 1,4,5‐Trisphosphate Formation, and so Mobilize Ca2+ from Intracellular Stores, in Undifferentiated NG108‐15 Cells

  1996cited by this paper
• delta-Opioids stimulate inositol 1,4,5-trisphosphate formation, and so mobilize Ca2+ from intracellular stores, in undifferentiated NG108-15 cells.

  1996cited by this paper
• Relevance of phosphorylation state to opioid responsiveness in opiate naive and tolerant/dependent tissue.

  1996cited by this paper
• Protein kinase C inhibits the Ca(2+)-dependent stimulation of phospholipase C-beta 1 in vitro.

  1996cited by this paper
• Biochemical adaptations in the mesolimbic dopamine system in response to heroin self‐administration

  1995cited by this paper
• Mu-opioids activate phospholipase C in SH-SY5Y human neuroblastoma cells via calcium-channel opening.

  1995cited by this paper
• Increases in protein kinase C gamma immunoreactivity in the spinal cord of rats associated with tolerance to the analgesic effects of morphine.

  1995cited by this paper
• The development of morphine tolerance and dependence is associated with translocation of protein kinase C

  1995cited by this paper
• The association of neuropathic pain, morphine tolerance and dependence, and the translocation of protein kinase C.

  1995cited by this paper
• Homologous and heterologous regulation of receptor-stimulated phosphoinositide hydrolysis.

  1995cited by this paper
• Expressed mu opiate receptor couples to adenylate cyclase and phosphatidyl inositol turnover.

  1994cited by this paper
• Opioids mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells

  1994cited by this paper
• μ‐Opioid Receptor Stimulation of Inositol (1,4,5)Trisphosphate Formation via a Pertussis Toxin‐Sensitive G Protein

  1994cited by this paper
• Mu- and kappa-opioid receptors selectively reduce the same transient components of high-threshold calcium current in rat dorsal root ganglion sensory neurons

  1994cited by this paper
• Two forms of phospholipase C-beta 1 generated by alternative splicing.

  1994cited by this paper
• Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits.

  1993cited by this paper
• δ Opioid receptor mediates phospholipase C activation via Gi in Xenopus oocytes

  1993cited by this paper
• An enzymatic mechanism for potassium channel stimulation through pertussis-toxin-sensitive G proteins.

  1992cited by this paper
• Specific inhibition of calcineurin by type II synthetic pyrethroid insecticides.

  1992cited by this paper
• Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats.

  1992cited by this paper
• Molecular mechanisms of drug addiction [published erratum appears in J Neurosci 1992 Aug;12(8):following table of contents]

  1992cited by this paper
• Opioid receptor-coupled second messenger systems

  1991cited by this paper
• Activation of mu opioid receptors inhibits transient high- and low-threshold Ca2+ currents, but spares a sustained current.

  1991cited by this paper
• Opioid receptor-coupled second messenger systems.

  1991cited by this paper
• Feedback regulation of phospholipase C-beta by protein kinase C.

  1990cited by this paper
• Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: regulation by acute and chronic morphine

  1989cited by this paper
• Inositol phosphates and cell signalling

  1989cited by this paper
• Calyculin A and okadaic acid: inhibitors of protein phosphatase activity.

  1989cited by this paper
• Chronic morphine treatment increases cyclic AMP-dependent protein kinase activity in the rat locus coeruleus.

  1988cited by this paper
• Acute and chronic opiate-regulation of adenylate cyclase in brain: specific effects in locus coeruleus.

  1988cited by this paper
• Morphine withdrawal in vitro: potentiation of agonist-dependent polyphosphoinositide breakdown.

  1988cited by this paper
• Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.

  1987cited by this paper
• Opiate-dependent modulation of adenylate cyclase.

  1977cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Dual regulation of adenylate cyclase accounts for narcotic dependence and tolerance.

  1975cited by this paper
• Morphine receptors as regulators of adenylate cyclase activity.

  1975cited by this paper

• Disrupting Spinal Caveolin-1 Scaffolding Prevents as well as Reverses Tolerance to Opioid Antiallodynia in Treating Neuropathic Pain in Rats

  2022cites this paper
• Phospholipase Cβ2 Promotes Vascular Endothelial Growth Factor Induced Vascular Permeability

  2022cites this paper
• Inhibition of orexin receptor 1 contributes to the development of morphine dependence via attenuation of cAMP response element-binding protein and phospholipase Cβ3.

  2020cites this paper
• Selective up‐regulation of functional mu‐opioid receptor splice variants by chronic opioids

  2016cites this paper
• A1-adenosine acute withdrawal response and cholecystokinin-8 induced contractures are regulated by Ca(2+)- and ATP-activated K(+) channels.

  2015cites this paper
• Revealing the role of phospholipase Cβ3 in the regulation of VEGF-induced vascular permeability.

  2012cites this paper
• Global Changes in the Rat Heart Proteome Induced by Prolonged Morphine Treatment and Withdrawal

  2012cites this paper
• Direct association of Mu-opioid and NMDA glutamate receptors supports their cross-regulation: molecular implications for opioid tolerance.

  2012cites this paper
• A Unique Role of RGS9-2 in the Striatum as a Positive or Negative Regulator of Opiate Analgesia

  2011cites this paper
• RGSZ2 Binds to the Neural Nitric Oxide Synthase PDZ Domain to Regulate Mu-Opioid Receptor-Mediated Potentiation of the N-Methyl-D-Aspartate Receptor-Calmodulin-Dependent Protein Kinase II Pathway

  2011cites this paper
• AUniqueRoleofRGS9-2intheStriatumasaPositiveor NegativeRegulatorofOpiateAnalgesia

  2011cites this paper
• Acute withdrawal induced by adenosine A-receptor activation in isolated guinea-pig ileum: role of opioid receptors and effect of cholecystokinin.

  2010cites this paper
• Regulation of facial morphogenesis by endothelin signaling: Insights from mice and fish

  2010cites this paper
• Acute withdrawal induced by adenosine A1‐receptor activation in isolated guinea‐pig ileum: role of opioid receptors and effect of cholecystokinin

  2010cites this paper
• Down-regulation of c-Cbl by Morphine Accounts for Persistent ERK1/2 Signaling in δ-Opioid Receptor-expressing HEK293 Cells

  2009cites this paper
• Wagging the tail : a case of curtailing G q-mediated PLC activation in living cells

  2008cites this paper
• Do pharmacological approaches that prevent opioid tolerance target different elements in the same regulatory machinery?

  2008cites this paper
• Capsaicin inhibits the in vitro binding of peptides selective for mu- and kappa-opioid, and nociceptin-receptors.

  2008cites this paper
• Properties of phospholipase C-β-mediated signaling in H9c2 cardiac myoblasts

  2007cites this paper
• phospholipase C, beta 3 is required for Endothelin1 regulation of pharyngeal arch patterning in zebrafish.

  2007cites this paper
• Phosphorylation of Gs α influences its association with the mu-opioid receptor and is modulated by chronic morphine

  2007cites this paper
• Opioid elevation of intracellular free calcium: possible mechanisms and physiological relevance.

  2006cites this paper
• Phospholipase Cbeta1 modulates pain sensitivity, opioid antinociception and opioid tolerance formation.

  2006cites this paper
• Mu and kappa opioid receptors activate ERK/MAPK via different protein kinase C isoforms and secondary messengers in astrocytes.

  2005cites this paper
• μ and κ Opioid Receptors Activate ERK/MAPK via Different Protein Kinase C Isoforms and Secondary Messengers in Astrocytes*

  2005cites this paper
• Chronic morphine-induced loss of the facilitative interaction between vasoactive intestinal polypeptide and delta-opioid: involvement of protein kinase C and phospholipase Cbetas.

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• Endogenous opiates and behavior: 2003.

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