Double-Strand Break Repair Gene Polymorphisms and Risk of Breast or Ovarian Cancer

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Cancer Epidemiology, Biomarkers and Prevention

• Publication date

  2005-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/1055-9965.EPI-04-0335PMID 15734952
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the Breast Cancer Family Registry.

  2004cited by this paper
• XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells

  2004cited by this paper
• DNA repair gene polymorphisms, pre-natal factors and the frequency of somatic mutations in the glycophorin-A gene among healthy newborns.

  2004cited by this paper
• Breast cancer risk reduction associated with the RAD51 polymorphism among carriers of the BRCA1 5382insC mutation in Poland.

  2003cited by this paper
• Polymorphisms in DNA double-strand break repair genes and breast cancer risk in the Nurses' Health Study.

  2003cited by this paper
• DNA-repair genetic polymorphisms and breast cancer risk.

  2003cited by this paper
• Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA.

  2003cited by this paper
• No association between the DNA repair gene XRCC3 T241M polymorphism and risk of skin cancer and breast cancer.

  2003cited by this paper
• A naturally occurring mutation in an ATP-binding domain of the recombination repair gene XRCC3 ablates its function without causing cancer susceptibility.

  2003cited by this paper
• Polymorphisms of XRCC1 and XRCC3 genes and susceptibility to breast cancer.

  2003cited by this paper
• Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks

  2002cited by this paper
• A potential role for the XRCC2 R188H polymorphic site in DNA-damage repair and breast cancer.

  2002cited by this paper
• Low-penetrance susceptibility to breast cancer due to CHEK2*1100delC in noncarriers of BRCA1 or BRCA2 mutations

  2002cited by this paper
• Dominant negative ATM mutations in breast cancer families.

  2002cited by this paper
• A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer.

  2002cited by this paper
• Diagnostic x-rays and risk of epithelial ovarian carcinoma in Jews.

  2002cited by this paper
• Variants in DNA double-strand break repair genes and breast cancer susceptibility.

  2002influential reference
• The progesterone receptor exon 4 Val660Leu G/T polymorphism and risk of breast cancer in Australian women.

  2002cited by this paper
• The microsomal epoxide hydrolase Tyr113His polymorphism: Association with risk of ovarian cancer

  2001cited by this paper
• A single nucleotide polymorphism in the RAD51 gene modifies cancer risk in BRCA2 but not BRCA1 carriers

  2001cited by this paper
• Excess breast cancer risk and the role of parity, age at first childbirth and exposure to radiation in infancy

  2001cited by this paper
• A single nucleotide polymorphism in the 5' untranslated region of RAD51 and risk of cancer among BRCA1/2 mutation carriers.

  2001cited by this paper
• No significant association between progesterone receptor exon 4 Val660Leu G/T polymorphism and risk of ovarian cancer.

  2001cited by this paper
• In search of the tumour-suppressor functions of BRCA1 and BRCA2

  2000cited by this paper
• Design and analysis issues in a population-based, case-control-family study of the genetic epidemiology of breast cancer and the Co-operative Family Registry for Breast Cancer Studies (CFRBCS).

  1999cited by this paper
• ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer.

  1998cited by this paper
• Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men

  1997cited by this paper
• Deficient DNA repair capacity, a predisposing factor in breast cancer.

  1996cited by this paper
• Reproductive and other factors and risk of epithelial ovarian cancer: An australian case‐control study

  1995cited by this paper
• Radiation and other environmental exposures and breast cancer.

  1993cited by this paper
• Malignant disease after radiation treatment of benign gynaecological disorders. A study of a cohort of metropathia patients.

  1990cited by this paper
• Breast cancer in women with scoliosis exposed to multiple diagnostic x rays.

  1989cited by this paper
• Malignant and benign ovarian neoplasms among atomic bomb survivors, Hiroshima and Nagasaki, 1950-80.

  1987cited by this paper
• Long term mortality after a single treatment course with X-rays in patients treated for ankylosing spondylitis.

  1987cited by this paper

• Association Between Seven Selected Genetic Polymorphisms in DNA Repair-Related Genes and Breast Cancer Risk: Evidence from a Comprehensive Meta-analysis Including 96 Studies.

  2025cites this paper
• Systematic evaluation of the association between a missense variant in XRCC3 gene splicing site and the pathogenesis of ovarian cancer

  2023cites this paper
• Relationship between polymorphisms in homologous recombination repair genes RAD51 G172T、XRCC2 & XRCC3 and risk of breast cancer: A meta-analysis

  2023cites this paper
• The association between single nucleotide polymorphisms and ovarian cancer risk: A systematic review and network meta‐analysis

  2022cites this paper
• Association between XRCC3 rs861539 Polymorphism and the Risk of Ovarian Cancer: Meta-Analysis and Trial Sequential Analysis

  2022cites this paper
• Association between XRCC3 Thr241Met polymorphism and risk of gynecological malignancies: A meta-analysis.

  2021cites this paper
• Analysis of the association between the XRCC2 rs3218536 polymorphism and ovarian cancer risk

  2020cites this paper
• Genetic polymorphisms in DNA repair genes XRCC1 and 3 are associated with increased risk of breast cancer in Bangladeshi population

  2020cites this paper
• Associations between XRCC3 Thr241Met polymorphisms and breast cancer risk: systematic-review and meta-analysis of 55 case-control studies

  2019cites this paper
• Association of XRCC3 18067 C>T (Thr241Met) polymorphism with risk of cervical and ovarian cancers: A systematic review and meta-analysis

  2019cites this paper
• Prognostic Significance of Platelet-lymphocyte Ratio in Hepatocellular Carcinoma Patients: A Meta-analysis

  2018influential citation
• Genetic determinants of sporadic breast cancer in Sri Lankan women

  2018cites this paper
• DNA Repair Mechanism Gene, XRCC1A (Arg194Trp) but not XRCC3 (Thr241Met) Polymorphism Increased the Risk of Breast Cancer in Premenopausal Females: A Case–Control Study in Northeastern Region of India

  2017cites this paper
• Association of XRCC2 rs3218536 Polymorphism with Susceptibility of Breast and Ovarian Cancer: A Systematic Review and Meta-Analysis

  2017influential citation
• RAD 51 ( rs 1801320 ) gene polymorphism and breast cancer risk in Turkish population

  2017cites this paper
• RAD 51 Gene 135 G / C polymorphism and ovarian cancer risk : a meta-analysis

  2016cites this paper
• Association between single nucleotide polymorphisms (SNPs) of XRCC2 and XRCC3 homologous recombination repair genes and ovarian cancer in Polish women.

  2016cites this paper
• Associations between XRCC2 rs3218536 and ERCC2 rs13181 polymorphisms and ovarian cancer

  2016cites this paper
• Association between ERCC 2 rs 13181 and XRCC 2 rs 3218536 polymorphisms and the risk of ovarian cancer : a meta-analysis

  2016cites this paper
• RAD51 135G>C substitution increases breast cancer risk in an ethnic-specific manner: a meta-analysis on 21236 cases and 19407 controls

  2015cites this paper
• Association between RAD 51 polymorphism and breast cancer susceptibility : a meta analysis

  2015influential citation
• Lack of an association between XRCC2 R188H polymorphisms and breast cancer: an update meta-analysis involving 35,422 subjects.

  2015cites this paper
• Impact of RAD51 G135C and XRCC1 Arg399Gln polymorphisms on ovarian carcinoma risk in Serbian women

  2015cites this paper
• Arg188His polymorphism in the XRCC2 gene and the risk of ovarian cancer: a meta-analysis.

  2015cites this paper
• RAD51 Gene 135G/C polymorphism and ovarian cancer risk: a meta-analysis.

  2015cites this paper
• Association between RAD51 polymorphism and breast cancer susceptibility: a meta analysis.

  2015cites this paper
• DNA REPAIR GENE XRCC3 241MET VARIANT AND BREAST CANCER SUSCEPTIBILITY OF AZERI POPULATIONIN IRANIAN

  2015cites this paper
• RAD51 135G>C Polymorphism and Cancer Risk: An Updated Meta-Analysis Involving 54,239 Subjects

  2015cites this paper
• RAD51 Gene 135G/C polymorphism and the risk of four types of common cancers: a meta-analysis

  2014cites this paper
• Relationship between Rad51 G135C and G172T Variants and the Susceptibility to Cancer: A Meta-Analysis Involving 54 Case-Control Studies

  2014cites this paper
• An increased risk of ovarian cancer associated with polymorphism in BRCC5 gene in Caucasian populations

  2014cites this paper
• Analyzing Association of the XRCC3 Gene Polymorphism with Ovarian Cancer Risk

  2014cites this paper
• An association between the −41657 C/T polymorphism of X-ray repair cross-complementing 2 (XRCC2) gene and ovarian cancer

  2014cites this paper
• Association between the XRCC3 Thr241Met polymorphism and breast cancer risk: an updated meta-analysis of 36 case-control studies.

  2014cites this paper
• The Relationship between Seven Common Polymorphisms from Five DNA Repair Genes and the Risk for Breast Cancer in Northern Chinese Women

  2014cites this paper
• The Arg188His polymorphism in the XRCC2 gene and the risk of cancer

  2014influential citation
• The effect of RAD51 135 G>C and XRCC2 G>A (rs3218536) polymorphisms on ovarian cancer risk among Caucasians: a meta-analysis

  2014cites this paper
• Genetic 135G/C polymorphism of RAD51 gene and risk of cancer: a meta-analysis of 28,956 cases and 28,372 controls

  2014cites this paper
• Impact of XRCC2 Arg188His Polymorphism on Cancer Susceptibility: A Meta-Analysis

  2014cites this paper
• Association of polymorphisms in the 5′ untranslated region of RAD51 gene with risk of endometrial cancer in the Polish population

  2014cites this paper
• Association between the XRCC3 T241M polymorphism and risk of cancer: evidence from 157 case-control studies.

  2013cites this paper
• DNA repair and cytotoxic drugs: the potential role of RAD51 in clinical outcome of non-small-cell lung cancer patients.

  2013cites this paper
• Association between the RAD51 135 G>C Polymorphism and Risk of Cancer: A Meta-Analysis of 19,068 Cases and 22,630 Controls

  2013cites this paper
• Synthetic Lethality between Gene Defects Affecting a Single Non-essential Molecular Pathway with Reversible Steps

  2013cites this paper
• XRCC3 Thr241Met polymorphism and ovarian cancer risk: a meta-analysis

  2013cites this paper
• Association between polymorphisms of the DNA repair gene RAD51 and ovarian cancer.

  2013cites this paper
• The association between polymorphisms of the RAD51-G135C, XRCC2-Arg188His and XRCC3-Thr241Met genes and clinico-pathologic features in breast cancer in Poland.

  2012cites this paper
• Sapacitabine for cancer

  2012cites this paper
• Single nucleotide polymorphisms of RAD51 G135C, XRCC2 Arg188His and XRCC3 Thr241Met homologous recombination repair genes and the risk of sporadic endometrial cancer in Polish women

  2012cites this paper
• A single nucleotide polymorphism in the 5' untranslated region of RAD51 and ovarian cancer risk in Polish women.

  2012cites this paper
• RAD51 135G/C polymorphism and breast cancer risk: a meta-analysis from 21 studies

  2011cites this paper
• RAD51 135G>C does not modify breast cancer risk in non-BRCA1/2 mutation carriers: evidence from a meta-analysis of 12 studies

  2011cites this paper
• DNA Damage Repair and Cancer: The Role of RAD51 Protein and Its Genetic Variants

  2011cites this paper
• Association between the p53 polymorphisms and breast cancer risk: meta-analysis based on case–control study

  2011cites this paper
• Single nucleotide polymorphisms in the homologous recombination repair genes and breast cancer risk in Polish women.

  2011cites this paper
• Genetic susceptibility to sporadic ovarian cancer: a systematic review.

  2011cites this paper
• Association between the XRCC3 polymorphisms and breast cancer risk: meta-analysis based on case–control studies

  2011cites this paper
• Need for clarification of data in the recent meta-analysis about RAD51 135G>C polymorphism and breast cancer risk

  2011cites this paper
• XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3)

  2011cites this paper
• Combined effect of polymorphisms in Rad51 and Xrcc3 on breast cancer risk and chromosomal radiosensitivity.

  2011cites this paper
• RAD51 135G>C polymorphism and breast cancer risk: a meta-analysis

  2010influential citation
• Polymorphisms of the XRCC3 C722T and the RAD51 G135C genes and the risk of head and neck cancer in a Polish population.

  2010cites this paper
• RAD51 135G>C polymorphism contributes to breast cancer susceptibility: a meta-analysis involving 26,444 subjects

  2010cites this paper
• XRCC2 Arg188His polymorphism is not directly associated with breast cancer risk: evidence from 37,369 subjects

  2010cites this paper
• Genetic susceptibility to breast cancer

  2010cites this paper
• Variants in DNA double-strand break repair genes and risk of familial breast cancer in a South American population

  2010cites this paper
• Breast cancer risk and common single nucleotide polymorphisms in homologous recombination DNA repair pathway genes XRCC2, XRCC3, NBS1 and RAD51.

  2010cites this paper
• RAD51 G135C polymorphism is associated with breast cancer susceptibility: a meta-analysis involving 22,399 subjects

  2010cites this paper
• XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis

  2010cites this paper
• XRCC2 Arg188His polymorphism is not directly associated with breast cancer risk: evidence from 37,369 subjects

  2010cites this paper
• Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium

  2009cites this paper
• Genetic Modifiers of Risk of BRCA1 - and BRCA2 -Related Breast and Ovarian Cancers

  2009cites this paper
• Validating genetic risk associations for ovarian cancer through the International Ovarian Cancer Association Consortium

  2009cites this paper
• XRCC1 and XRCC3 DNA repair gene polymorphisms in breast cancer women from the Lodz region of Poland.

  2009cites this paper
• An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses

  2009cites this paper
• Genetic variations in DNA repair genes, radiosensitivity to cancer and susceptibility to acute tissue reactions in radiotherapy-treated cancer patients

  2008cites this paper
• Null Results in Brief Polymorphisms in RAD51, XRCC2, and XRCC3 Are Not Related to Breast Cancer Risk

  2008cites this paper
• The ERCC4/XPF gene polymorphism in postmenopausal women with breast cancer

  2008cites this paper
• DNA repair enzyme genotypes and their toxicologically relevant phenotypes.

  2008cites this paper
• Association between DNA damage, DNA repair genes variability and clinical characteristics in breast cancer patients.

  2008cites this paper
• Polymorphisms in RAD51, XRCC2, and XRCC3 Are Not Related to Breast Cancer Risk

  2008cites this paper
• A naturally occurring genetic variant of human XRCC2 (R188H) confers increased resistance to cisplatin-induced DNA damage.

  2007cites this paper
• Genetic polymorphism of XRCC3 Thr241Met and breast cancer risk: case-control study in Korean women and meta-analysis of 12 studies

  2007cites this paper
• Association Between Single-Nucleotide Polymorphisms in Hormone Metabolism and DNA Repair Genes and Epithelial Ovarian Cancer: Results from Two Australian Studies and an Additional Validation Set

  2007cites this paper
• Ovarian cancer survival and polymorphisms in hormone and DNA repair pathway genes.

  2007cites this paper
• The MnSOD Val9Ala polymorphism, dietary antioxidant intake, risk and survival in ovarian cancer (Australia).

  2007cites this paper
• Commonly studied single-nucleotide polymorphisms and breast cancer: results from the Breast Cancer Association Consortium.

  2007cites this paper
• Molecular Epidemiology of DNA Repair and Cancer Susceptibility — A Review of Population-based Studies

  2007cites this paper
• DNA repair polymorphisms might contribute differentially on familial and sporadic breast cancer susceptibility: a study on a Portuguese population

  2007cites this paper
• RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.

  2007cites this paper
• Commonly studied single-nucleotide polymorphisms and breast cancer: Results from the Breast Cancer Association Consortium

  2006cites this paper
• Candidate single nucleotide polymorphism selection using publicly available tools: a guide for epidemiologists.

  2006cites this paper
• Polymorphisms in DNA double-strand break repair genes and risk of breast cancer: two population-based studies in USA and Poland, and meta-analyses

  2006influential citation
• DNA repair gene XRCC3 polymorphisms and cancer risk: a meta-analysis of 48 case–control studies

  2006cites this paper
• Review Article DNA Signalling/Repair Genetic Polymorphisms and Breast Cancer Risk: a Review

  2005cites this paper
• DNA Signalling/Repair Genetic Polymorphisms and BreastCancer Risk: a Review

  2005cites this paper