Over-expression of FRZB in gastric cancer cell suppresses proliferation and induces differentiation

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Cancer Research and Clinical Oncology

• Publication date

  2008-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00432-007-0291-0PMID 17680269PMCID PMC12161657
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gastric cancer.

  2013cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2005cited by this paper
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  2004influential reference
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  2003cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper

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