The Role of Alpha-2 Adrenergic Receptors in Anti-ulcer Activity.

Although peptic ulcer disease has long been recognized, the proposed mechanisms of its etiopathogenesis change every year. This review shows that gastric ulcers have a significant relationship with alpha-2 adrenergic receptors. The aggravating factors of gastric ulcer formation have been reported to act by blocking alpha-2 adrenergic receptors, whereas drugs possessing anti-ulcer activity have been shown to ensure gastric protection by stimulating the alpha-2 adrenergic receptors. The data derived from the literature indicate the likelihood that any drug or substance selectively stimulating the alpha-2 adrenergic receptors may possess anti-ulcer activity.

• Publication year

  2012

• Venue

  Eurasian Journal of Medicine

• Publication date

  2012-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.5152/eajm.2012.09PMID 25610204PMCID PMC4261408
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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