Wild-type p53-induced phosphatase 1 (Wip1) forestalls cellular premature senescence at physiological oxygen levels by regulating DNA damage response signaling during DNA replication

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Cell Cycle

• Publication date

  2014-01-31

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4161/cc.27920PMID 24552809PMCID PMC3984300
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Down-regulation of Wild-type p53-induced Phosphatase 1 (Wip1) Plays a Critical Role in Regulating Several p53-dependent Functions in Premature Senescent Tumor Cells*

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  2024influential citation
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  2022cites this paper
• Low WIP1 Expression Accelerates Ovarian Aging by Promoting Follicular Atresia and Primordial Follicle Activation

  2022cites this paper
• The inhibition of WIP1 phosphatase accelerates the depletion of primordial follicles.

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• Targeting oncogenic WIP1 phosphatase sensitizes hypoxic breast cancer cells to doxorubicin induced apoptosis via activation of p53-p21 axis

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• CDK5RAP2 loss-of-function causes premature cell senescence via the GSK3β/β-catenin-WIP1 pathway

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