We examined the role of the amygdala in the modulation of sleep and ponto-geniculo-occipital (PGO) waves in the rat. The amygdala projects massively, via its central nucleus, into brainstem regions involved in alerting and in the generation of rapid-eye movement (REM) sleep and PGO waves. Electrical stimulation of the central nucleus of the amygdala during REM sleep increased PGO wave amplitude. Stimulation during non-REM sleep decreased PGO wave frequency. The results indicate that the amygdala has a role in modulating brainstem neural mechanisms underlying alerting during sleep.
Effects of electrical stimulation in the amygdala on ponto-geniculo-occipital waves in rats.
T. Deboer,L. Sanford,R. Ross,A. Morrison
Published 1998 in Brain Research
ABSTRACT
PUBLICATION RECORD
- Publication year
1998
- Venue
Brain Research
- Publication date
1998-05-18
- Fields of study
Biology, Medicine, Psychology
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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