Extracellular increase of hypoxanthine and xanthine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Brain Research

• Publication date

  1989-01-30

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/0006-8993(89)91504-7PMID 2924128
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of Theophylline on Ischemically Induced Hippocampal Damage in Mongolian Gerbils: A Behavioral and Histopathological Study

  1987cited by this paper
• Interstitial Fluid Adenosine and Sagittal Sinus Blood Flow during Bicuculline-Seizures in Newborn Piglets

  1987cited by this paper
• Postasphyxial Cerebral Survival in Newborn Sheep after Treatment with Oxygen Free Radical Scavengers and a Calcium Antagonist

  1987cited by this paper
• Extracellular Adenosine, Inosine, Hypoxanthine, and Xanthine in Relation to Tissue Nucleotides and Purines in Rat Striatum During Transient Ischemia

  1987cited by this paper
• Extracellular overflow of glutamate, aspartate, GABA and taurine in the cortex and basal ganglia of fetal lambs during hypoxia-ischemia.

  1987cited by this paper
• 31P-NMR studies of cerebral metabolic changes during graded hypoxia in newborn lambs.

  1987cited by this paper
• Extracellular Overflow of Neuroactive Amino Acids During Severe Insulin‐Induced Hypoglycemia: In Vivo Dialysis of the Rat Hippocampus

  1986cited by this paper
• Oxygen-derived free radicals in postischemic tissue injury.

  1985cited by this paper
• Effects of Anoxia on Cerebral Blood Flow in the Rat Brain: Evidence for a Role of Adenosine in Autoregulation

  1984cited by this paper
• Contribution of heart muscle, liver, skeletal muscle and placenta to the asphyxial hypoxanthine elevation in the acutely exteriorised fetal lamb.

  1984cited by this paper
• Brain ischemic anoxia. Mechanisms of injury.

  1984cited by this paper
• Stereotaxic method and atlas for the ovine fetal forebrain.

  1983cited by this paper
• Cerebral arterio-venous difference for hypoxanthine and lactate during graded asphyxia in the fetal lamb.

  1982cited by this paper
• Hypoxanthine production by ischemic heart demonstrated by high pressure liquid chromatography of blood purine nucleosides and oxypurines.

  1981cited by this paper
• ADENINE NUCLEOTIDES AND SYNAPTIC TRANSMISSION IN THE in vitro RAT HIPPOCAMPUS

  1980cited by this paper
• Plasma Hypoxanthine in Exteriorized, Acutely Asphyxiated Fetal Lambs

  1980cited by this paper
• Identification and quantitation of nucleosides, bases and other UV-absorbing compounds in serum, using reversed-phase high-performance liquid chromatography. I. Chromatographic methodology.

  1979cited by this paper
• Identification and quantitation of nucleosides, bases and other UV-absorbing compounds in serum, using reversed-phase high-performance liquid chromatography. II. Evaluation of human sera.

  1979cited by this paper
• Identification and quantitation of nucleosides, bases and other UV-absorbing compounds in serum, using reversed-phase high-performance liquid chromatography : II. Evaluation of human era

  1979cited by this paper
• Post-mortem hypoxanthine levels in the vitreous humour. An introductory report.

  1978cited by this paper
• Post mortem hypo xanthine levels in the vitreous humor an introductory report

  1978cited by this paper
• Measurement of cerebral blood flow in the fetal lamb with a note on the flow-distribution.

  1978cited by this paper
• The dilatatory action of adenosine on pial arteries of cats and its inhibition by theophylline

  1976cited by this paper
• Alteration of the hypoxanthine level in cerebrospinal fluid as an indicator of tissue hypoxia.

  1976cited by this paper
• Changes in the ECG and Somatosensory-Evoked EEG Responses during Intrauterine Asphyxia in the Sheep

  1976cited by this paper
• Alterations in Fetal Heart Rate and ECG Correlated to Glycogen, Creatine Phosphate and ATP Levels during Graded Hypoxia

  1976cited by this paper
• Hypoxanthine as a Measurement of Hypoxia

  1975cited by this paper
• PURINE NUCLEOTIDE METABOLISM IN THE CAT BRAIN AFTER ONE HOUR OF COMPLETE ISCHEMIA

  1974cited by this paper
• Release of Adenosine from Ischemic Brain: Effect on Cerebral Vascular Resistance and Incorporation into Cerebral Adenine Nucleotides

  1974cited by this paper
• Changes in energy state and acid-base parameters of the rat brain during complete compression ischemia.

  1974cited by this paper
• Cerebral Reactions during Intrauterine Asphyxia in the Sheep. I. Circulation and Oxygen Consumption in the Fetal Brain

  1974cited by this paper

• A non-purine inhibitor of xanthine oxidoreductase mitigates adenosine triphosphate degradation under hypoxic conditions in mouse brain.

  2025cites this paper
• Purine nucleoside use as surrogate markers of cerebral ischaemia during local and general anaesthetic carotid endarterectomy

  2019cites this paper
• Intracerebral microdialysis of adenosine and adenosine monophosphate – a systematic review and meta‐regression analysis of baseline concentrations

  2018cites this paper
• Pathophysiology: General Principles

  2018cites this paper
• Allopurinol: Old Drug, New Indication in Neonates?

  2018cites this paper
• Proof of concept and feasibility studies examining the influence of combination ribose, adenine and allopurinol treatment on stroke outcome in the rat

  2017cites this paper
• Blood purine measurements as a rapid real-time indicator of reversible brain ischaemia

  2017cites this paper
• The fetal brain sparing response to hypoxia: physiological mechanisms

  2016cites this paper
• Selective Regulation of Oocyte Meiotic Events Enhances Progress in Fertility Preservation Methods

  2015cites this paper
• Animal Models of Neurodevelopmental Disorders

  2015cites this paper
• Fetal Brain Activity in the Sheep Model with Intrauterine Hypoxia

  2015cites this paper
• Selective Regulation of Oocyte Meiotic Events Enhances Progress in Fertility Preservation Methods

  2015cites this paper
• Identification, mechanisms and treatment of perinatal brain injury

  2014cites this paper
• Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes

  2013cites this paper
• Cerebral metabolism during acute liver failure and the effect of treatment with fractionated plasma separation and

  2011cites this paper
• On neonatal asphyxia : clinical and animal studies including development of a simple, safe method for therapeutic hypothermia with global applicability

  2011cites this paper
• Hypoxic ischemic encephalopathy : Diagnosis, hypothermia treatment and outcome

  2010cites this paper
• Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

  2010cites this paper
• The effect of infusing hypoxanthine or xanthine on hypoxic-ischemic brain injury in rabbits.

  2007cites this paper
• White Matter Injury Following Prolonged Free Radical Formation in the 0.65 Gestation Fetal Sheep Brain

  2005cites this paper
• The use of intensity modulated optical spectroscopy to measure cerebral saturation and haemoglobin concentration in the human fetus during labour

  2005cites this paper
• Purine and Pyrimidine Metabolism and Electrocortical Brain Activity during Hypoxemia in Near-Term Lambs

  2004cites this paper
• Adenosine Mediates Decreased Cerebral Metabolic Rate and Increased Cerebral Blood Flow During Acute Moderate Hypoxia in the Near‐Term Fetal Sheep

  2003cites this paper
• Effects of maternal oxygen supplementation on fetal oxygenation and lipid peroxidation following a single umbilical cord occlusion in fetal goats.

  2003cites this paper
• Key neuroprotective role for endogenous adenosine A1 receptor activation during asphyxia in the fetal sheep.

  2003cites this paper
• The Role of Adenosine in Regulation of Cerebral Blood Flow During Hypoxia in the Near‐Term Fetal Sheep

  2002cites this paper
• Reduced postnatal cerebral glucose metabolism measured by PET after asphyxia in near term fetal lambs

  2001cites this paper
• Adenosine A1 receptor agonism in the immature rat brain and heart

  2001cites this paper
• Neurobiology of Periventricular Leukomalacia in the Premature Infant

  2001cites this paper
• Adenosine A(1) receptor agonism in the immature rat brain and heart.

  2001cites this paper
• Changes in fetal plasma adenosine and xanthine concentrations during fetal asphyxia with maternal oxygen administration in ewes.

  2000cites this paper
• Free Radicals Are Formed in the Brain of Fetal Sheep during Reperfusion after Cerebral Ischemia

  1998cites this paper
• Intrapartum fetal hypoxia and biochemical markers: a review.

  1998cites this paper
• Pharmacological strategies for the prevention of perinatal brain damage

  1998cites this paper
• Effects of hypoxemia and reoxygenation with 21% or 100% oxygen in newborn piglets: extracellular hypoxanthine in cerebral cortex and femoral muscle.

  1997cites this paper
• Impact of reoxygenation with oxygen and air on the extent of the brain damage after hypoxia‐ischaemia in neonatal rats

  1996cites this paper
• Effects of the 21-Amino Steroid Tirilazad Mesylate (U-74006F) on Brain Damage and Edema after Perinatal Hypoxia-Ischemia in the Rat

  1996cites this paper
• Reduction in Cerebral Ischemic Injury in the Newborn Rat by Potentiation of Endogenous Adenosine

  1995cites this paper
• Purine metabolite washout and platelet aggregation at reflow after tourniquet ischemia: effect of intravenous regional lidocaine

  1995cites this paper
• Changes in adenosine receptors in the neonatal rat brain following hypoxic ischemia.

  1994cites this paper
• Hypoxic inhibition of breathing in fetal sheep: relationship to brain adenosine concentrations.

  1994cites this paper
• Effects of Surgery and Asphyxia on Levels of Nucleosides, Purine Bases, and Lactate in Cerebrospinal Fluid of Fetal Lambs

  1994cites this paper
• Brain Hypoxia: Metabolic and Ventilatory Depression

  1994cites this paper
• Relationship between ion gradients and neurotransmitter release in the newborn rat striatum during anoxia.

  1993cites this paper
• Transport of hypoxanthine from plasma to cerebrospinal fluid and vitreous humor in newborn pigs

  1993cites this paper
• Scavengers of Free Oxygen Radicals in Combination with Magnesium Ameliorate Perinatal Hypoxic-Ischemic Brain Damage in the Rat

  1993cites this paper
• Effects of asphyxia on the fetal lamb brain.

  1993cites this paper
• Extracellular levels of adenosine and its metabolites in the striatum of awake rats: inhibition of uptake and metabolism.

  1991cites this paper
• Oxygen free radicals and Parkinson's disease.

  1991cites this paper
• Mechanisms of perinatal brain damage.

  1991cites this paper
• Disturbed brain purine metabolism results in a gross opening of the blood-brain barrier in newborn piglets following experimental pneumothorax.

  1990cites this paper
• Excitatory amino acids in the developing brain: ontogeny, plasticity, and excitotoxicity.

  1990cites this paper
• Hydrocephalus‐Induced Changes in the Composition of Cerebrospinal Fluid

  1989cites this paper