The loss of adipokine genes in the chicken genome and implications for insulin metabolism.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Molecular biology and evolution

• Publication date

  2014-07-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/molbev/msu208PMID 25015647
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Discovery and characterization of the first genuine avian leptin gene in the rock dove (Columba livia).

  2014cited by this paper
• Discovery of a novel functional leptin protein (LEP) in zebra finches: evidence for the existence of an authentic avian leptin gene predominantly expressed in the brain and pituitary.

  2014cited by this paper
• Discovery of the Elusive Leptin in Birds: Identification of Several ‘Missing Links’ in the Evolution of Leptin and Its Receptor

  2014cited by this paper
• Nutritional signals and reproduction.

  2014cited by this paper
• All chromosomes great and small: 10 years on

  2014cited by this paper
• Structure, synthesis, and phylogeny of kisspeptin and its receptor.

  2013cited by this paper
• Adipokines Mediate Inflammation and Insulin Resistance

  2013cited by this paper
• Update on ghrelin biology in birds.

  2013cited by this paper
• Implications of leptin in neuroendocrine regulation of male reproduction.

  2013cited by this paper
• Leptin and reproductive function.

  2012cited by this paper
• Evolution of Genes Involved in Gamete Interaction: Evidence for Positive Selection, Duplications and Losses in Vertebrates

  2012cited by this paper
• Characterization of major elements of insulin signaling cascade in chicken adipose tissue: apparent insulin refractoriness.

  2012cited by this paper
• Proinflammatory Actions of Visfatin/Nicotinamide Phosphoribosyltransferase (Nampt) Involve Regulation of Insulin Signaling Pathway and Nampt Enzymatic Activity*

  2012cited by this paper
• Kisspeptins and reproduction: physiological roles and regulatory mechanisms.

  2012cited by this paper
• Excess of leptin inhibits hypothalamic KiSS-1 expression in pubertal mice

  2012cited by this paper
• Adipokines, Ghrelin and Obesity‐Associated Insulin Resistance in Nondiabetic Patients with Acute Coronary Syndrome

  2012cited by this paper
• Kisspeptins and the reproductive axis: potential applications to manage reproduction in farm animals.

  2012cited by this paper
• Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: a meta‐analysis and systemic review

  2011cited by this paper
• Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution.

  2010cited by this paper
• Integrative mapping analysis of chicken microchromosome 16 organization

  2010cited by this paper
• Is there a leptin gene in the chicken genome? Lessons from phylogenetics, bioinformatics and genomics.

  2010influential reference
• Molecular coevolution of kisspeptins and their receptors from fish to mammals

  2010cited by this paper
• Reply to viewpoints by PJ Sharp, IC Dunn, D Waddington and T Boswell [Chicken Leptin: General and Comparative Endocrinology, 158, 2-4 (2008)].

  2009cited by this paper
• Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals

  2009cited by this paper
• Yin-Yang Regulation of Adiponectin Signaling by APPL Isoforms in Muscle Cells*

  2009cited by this paper
• Spontaneous mapping of number and space in adults and young children.

  2009cited by this paper
• Insulin signaling in chicken liver and muscle.

  2009cited by this paper
• Genome size reduction in the chicken has involved massive loss of ancestral protein-coding genes.

  2008cited by this paper
• Addition of the microchromosome GGA25 to the chicken genome sequence assembly through radiation hybrid and genetic mapping

  2008cited by this paper
• Lack of Specificity of Commercially Available Antisera: Better Specifications Needed

  2008cited by this paper
• Chicken leptin receptor is functional in activating JAK-STATpathway in vitro.

  2008cited by this paper
• Insulin immuno-neutralization in chicken: effects on insulin signaling and gene expression in liver and muscle.

  2008cited by this paper
• Role of Chicken TL1A on Inflammatory Responses and Partial Characterization of Its Receptor

  2008cited by this paper
• Chicken leptin.

  2008cited by this paper
• Adipose tissue dysfunction in obesity, diabetes, and vascular diseases.

  2008cited by this paper
• The evolution of the ligand/receptor couple: a long road from comparative endocrinology to comparative genomics.

  2008cited by this paper
• The ‘beneficial’ adipokines in reproduction and fertility

  2008cited by this paper
• Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line.

  2007cited by this paper
• The chicken RH map: current state of progress and microchromosome mapping

  2007cited by this paper
• Molecular cloning and characterization of chicken lipopolysaccharide-induced TNF-α factor (LITAF)

  2006cited by this paper
• Molecular cloning and characterization of chicken lipopolysaccharide-induced TNF-alpha factor (LITAF).

  2006cited by this paper
• GPR54 and kisspeptin in reproduction.

  2006cited by this paper
• APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

  2006cited by this paper
• Epidemiology, trends, and morbidities of obesity and the metabolic syndrome

  2006cited by this paper
• PAI-1 and the Metabolic Syndrome: Links, Causes, and Consequences

  2006cited by this paper
• Activation of SOCS-3 by Resistin

  2005cited by this paper
• Mode of leptin action in chicken hypothalamus.

  2005cited by this paper
• An open letter to our readers on the use of antibodies

  2005cited by this paper
• Adipose tissue, adipokines, and inflammation.

  2005cited by this paper
• Chicken genome: current status and future opportunities.

  2005cited by this paper
• CARHTA GENE: multipopulation integrated genetic and radiation hybrid mapping

  2005cited by this paper
• Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution

  2004cited by this paper
• Insulin–glucose interactions characterised in newly hatched broiler chicks

  2003cited by this paper
• Redundancy in Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) Signaling In Vivo: Mice with Inactivation of the Entire TNF/LT Locus versus Single-Knockout Mice

  2002cited by this paper
• MapChart: software for the graphical presentation of linkage maps and QTLs.

  2002cited by this paper
• ChickRH6: a chicken whole-genome radiation hybrid panel

  2002cited by this paper
• Chicken leptin: properties and actions.

  2001cited by this paper
• The gene orders on human chromosome 15 and chicken chromosome 10 reveal multiple inter- and intrachromosomal rearrangements.

  2001cited by this paper
• A consensus linkage map of the chicken genome.

  2000cited by this paper
• Metabolic differences between genetically lean and fat chickens are partly attributed to the alteration of insulin signaling in liver.

  1999cited by this paper
• The dynamics of chromosome evolution in birds and mammals

  1999cited by this paper
• Cloning the chicken leptin gene.

  1998cited by this paper
• Cloning of the chicken insulin receptor substrate 1 gene.

  1996cited by this paper
• Corticosterone effect on insulin receptor number and kinase activity in chicken muscle and liver.

  1993cited by this paper
• Reptilian and avian follicular hierarchies: models for the study of ovarian development.

  1990cited by this paper
• Missing link

  1989cited by this paper
• Chicken as a useful species for the comprehension of insulin action

  1989cited by this paper
• Influence of age, strain, and beta-adrenergic agonist on insulin sensitivity in chicks as determined by an adaptation of the euglycemic clamp technique.

  1988cited by this paper
• Ovine luteinizing hormone-induced steroid and luteinizing hormone secretion, and ovulation in intact and pregnant mare serum gonadotropin-primed hens.

  1985cited by this paper
• Longitudinal study of adiposity in chickens selected for high or low abdominal fat content: further evidence of a glucose-insulin imbalance in the fat line.

  1982cited by this paper
• Evidence of a glucose-insulin imbalance and effect of dietary protein and energy level in chickens selected for high abdominal fat content.

  1981cited by this paper
• Biological characterization of chicken insulin activity in rats and domestic fowl.

  1968cited by this paper
• Bioinformatics Applications Note Genome Analysis Genomicus: a Database and a Browser to Study Gene Synteny in Modern and Ancestral Genomes

  year unknowncited by this paper

• Origins of Avian Hyperactive Mitochondria, Genome Compaction, and Air-Sac Physiology in Early Theropods During the Carnian Pluvial Episode

  2026cites this paper
• Genomic Insights into Abdominal and Intramuscular Fat Deposition in Chickens and Their Implications for Productivity Traits: A Systematic Review

  2026cites this paper
• Genetic innovations underlying the evolution of root nodule symbiosis in Leguminosae.

  2025cites this paper
• Genomic Introgression and Adaptation of Southern Seabird Species Facilitate Recent Polar Colonization

  2025cites this paper
• Cloning, phylogenetic analysis, tissue expression profiling, and functional roles of NPC1L1 in chickens, quails, and ducks

  2025cites this paper
• Large scale loss-of-function mutations during chicken evolution and domestication

  2024cites this paper
• Purinergic signaling during Marek’s disease in chickens

  2023cites this paper
• A chromosome-level genome assembly for the Silkie chicken resolves complete sequences for key chicken metabolic, reproductive, and immunity genes

  2023cites this paper
• The relationship between diet, plasma glucose, and cancer prevalence across vertebrates

  2023cites this paper
• The social environment alters neural responses to a lipopolysaccharide challenge.

  2023cites this paper
• Fourth Report on Chicken Genes and Chromosomes 2022

  2023cites this paper
• Gain or Loss? Evidence for Legume Predisposition to Symbiotic Interactions with Rhizobia via Loss of Pathogen-Resistance-Related Gene Families

  2022cites this paper
• Birth and Death in Terminal Complement Pathway

  2022cites this paper
• Expression Signatures of microRNAs and Their Targeted Pathways in the Adipose Tissue of Chickens during the Transition from Embryonic to Post-Hatch Development

  2021cites this paper
• Bird evolution by insulin resistance.

  2021cites this paper
• Adipokines in metabolic and reproductive functions in birds: an overview of current knowns and unknowns.

  2021cites this paper
• Peripheral regulation of food intake in chickens: adiposity signals, satiety signals and others

  2021cites this paper
• Chemerin impairs food intake and body weight in chicken: focus on hypothalamic neuropeptides gene expression and AMPK signaling pathway.

  2021cites this paper
• Should I Lay or Should I Grow: Photoperiodic Versus Metabolic Cues in Chickens

  2020cites this paper
• Molecular evolution of GIP and Exendin and their receptors.

  2020cites this paper
• Unravelling fatty liver haemorrhagic syndrome: 2. Inflammation and pathophysiology

  2020cites this paper
• Identification of a Novel Lipid Metabolism-Associated Hepatic Gene Family Induced by Estrogen via ERα in Chicken (Gallus gallus)

  2020cites this paper
• Effect of Different Levels of L-carnitine and Excess Lysine-Methionine on Broiler Performance, Carcass Characteristics, Blood Constituents, Immunity and Triiodothyronine Hormone

  2020cites this paper
• Long Non-coding RNA and mRNA Profile of Liver Tissue During Four Developmental Stages in the Chicken

  2020cites this paper
• Evidence for the loss of plasminogen receptor KT gene in chicken

  2020cites this paper
• Comparative analysis of the insect mobile genetic element repertoire and its influence on genome size dynamics

  2020cites this paper
• Avian Expression Patterns and Genomic Mapping Implicate Leptin in Digestion and TNF in Immunity, Suggesting That Their Interacting Adipokine Role Has Been Acquired Only in Mammals

  2019cites this paper
• Sequence properties of certain GC rich avian genes, their origins and absence from genome assemblies: case studies

  2019cites this paper
• The effect of &bgr;‐mannanase on nutrient utilization and blood parameters in chicks fed diets containing soybean meal and guar gum

  2018cites this paper
• Comparative omics and feeding manipulations in chicken indicate a shift of the endocrine role of visceral fat towards reproduction

  2018cites this paper
• A Dead Gene Walking: Convergent Degeneration of a Clade of MADS-Box Genes in Crucifers

  2018cites this paper
• Chicken Is a Useful Model to Investigate the Role of Adipokines in Metabolic and Reproductive Diseases

  2018cites this paper
• Dextran sulphate sodium (DSS) causes intestinal histopathology and inflammatory changes consistent with increased gut leakiness in chickens

  2018cites this paper
• Identification of biological factors that can be consistently linked to performance variation in modern commercial broiler flocks

  2017cites this paper
• Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost

  2017cites this paper
• Mapping of leptin and its syntenic genes to chicken chromosome 1p

  2017cites this paper
• Leptin as immune mediator: Interaction between neuroendocrine and immune system.

  2017cites this paper
• Evolution of the functionally conserved DCC gene in birds

  2017cites this paper
• On the Molecular Evolution of Leptin, Leptin Receptor, and Endospanin

  2017cites this paper
• Evolution of the vertebrate insulin receptor substrate (Irs) gene family

  2017cites this paper
• An Overall View of the Regulation of Hepatic Lipid Metabolism in Chicken Revealed by New-Generation Sequencing

  2017cites this paper
• Maternal consumption of fish oil programs reduced adiposity in broiler chicks

  2017cites this paper
• A dead gene walking: convergent degeneration of a clade of MADS-box genes in Brassicaceae

  2017cites this paper
• Identification of the Long-Sought Leptin in Chicken and Duck: Expression Pattern of the Highly GC-Rich Avian leptin Fits an Autocrine/Paracrine Rather Than Endocrine Function.

  2016cites this paper
• Discovery and functional characterization of leptin and its receptors in Japanese quail (Coturnix japonica).

  2016cites this paper
• Systematic analysis of the regulatory functions of microRNAs in chicken hepatic lipid metabolism

  2016cites this paper
• Genome-Wide Analysis Indicates Lineage-Specific Gene Loss during Papilionoideae Evolution

  2016cites this paper
• Decay of Sexual Trait Genes in an Asexual Parasitoid Wasp

  2016cites this paper
• Gene loss in plants: Evidence from genome‐wide phylogenetic analysis of thiamine pyrophosphate‐dependent enzymes

  2015cites this paper
• RNA-Seq Analysis of Abdominal Fat in Genetically Fat and Lean Chickens Highlights a Divergence in Expression of Genes Controlling Adiposity, Hemostasis, and Lipid Metabolism

  2015cites this paper
• Evolution of the Vertebrate Resistin Gene Family

  2015influential citation
• Transcriptome profile of liver at different physiological stages reveals potential mode for lipid metabolism in laying hens

  2015cites this paper
• Identification of Ohnolog Genes Originating from Whole Genome Duplication in Early Vertebrates, Based on Synteny Comparison across Multiple Genomes

  2015cites this paper
• Regulation of the avian central melanocortin system and the role of leptin.

  2015cites this paper