Signal transduction pathways involved in mechanical regulation of HB-GAM expression in osteoblastic cells.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2006-04-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BBRC.2006.02.063PMID 16513091
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2007influential citation
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