Binding of epidermal growth factor by human colon carcinoma cell (Caco-2) monolayers.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  1989-04-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0006-291X(89)91658-6PMID 2785387
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Epidermal growth factor receptor of the intestinal enterocyte. Localization to laterobasal but not brush border membrane.

  1989cited by this paper
• Presence and characteristics of epidermal growth factor receptors in human fetal small intestine and colon

  1988cited by this paper
• Specific receptors for epidermal growth factor in rat intestinal microvillus membranes.

  1988cited by this paper
• Transepithelial transport of epidermal growth factor by absorptive cells of suckling rat ileum.

  1987cited by this paper
• Polarized secretion of newly synthesized lipoproteins by the Caco-2 human intestinal cell line.

  1987cited by this paper
• Transferrin receptor polarity and recycling accuracy in "tight" and "leaky" strains of Madin-Darby canine kidney cells

  1986cited by this paper
• Effects of intraluminal epidermal growth factor on mucosal proliferation in the small intestine of adult rats.

  1986cited by this paper
• Epidermal growth factor receptors in isolated adult mouse intestinal cells: studies in vivo and in organ culture.

  1985cited by this paper
• 615 EGF-MEDIATED BREAST MILK-ENHANCED INTESTINAL GROWTH IN NEONATAL RATS

  1985cited by this paper
• Apical and basolateral endocytosis in Madin‐Darby canine kidney (MDCK) cells grown on nitrocellulose filters.

  1985cited by this paper
• Colostrum-Induced Enteric Mucosal Growth in Beagle Puppies

  1984cited by this paper
• Gastrointestinal absorption of epidermal growth factor in suckling rats.

  1984cited by this paper
• Properties of the receptor for epidermal growth factor.

  1984cited by this paper
• Serum and epidermal growth factor transiently depolarize quiescent BSC-1 epithelial cells.

  1982cited by this paper
• Demonstration of specific receptors for EGF—urogastrone in isolated rat intestinal epithelial cells

  1980cited by this paper
• Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

  1980cited by this paper
• Epidermal growth factor is a major growth-promoting agent in human milk.

  1980cited by this paper
• Ligand: a versatile computerized approach for characterization of ligand-binding systems.

  1980cited by this paper
• Epidermal growth factor.

  1979cited by this paper
• Epidermal growth factor: effects of androgens and adrenergic agents.

  1974cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Biological analysis of constituents in Spatholobi Caulis by UFLC-MS/MS: Enhanced quantification and application to permeability properties study in Caco-2 cell monolayer model.

  2023cites this paper
• AN IN VITRO STUDY OF MODULATORY EFFECTS OF SODIUM BICARBONATE ON HUMAN COLON ADENOCARCINOMA CELL (CACO-2)

  2014cites this paper
• 7. Permeability—PAMPA

  2012cites this paper
• Permeability: Caco‐2/MDCK

  2012cites this paper
• Hidalgo, I. J., Raub, T. J., and Borchardt, R. T.: Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability, Gastroenterology, 96, 736–749, 1989—The Backstory

  2011cites this paper
• The potential of silica nanoparticles as oral drug carriers

  2010cites this paper
• Phospholipids and Terpenes Enhance the Absorption of Polyphenolics in a Caco-2 Cell Model

  2010cites this paper
• Comparison of iron uptake from reduced iron powder and FeSO4 using the Caco-2 cell model: effects of ascorbic acid, phytic acid, and pH.

  2008cites this paper
• A Randomly Coiled, High-Molecular-Weight Polypeptide Exhibits Increased Paracellular Diffusion in Vitro and in Situ Relative to the Highly Ordered α-Helix Conformer

  2005influential citation
• The lectin-cell interaction and its implications to intestinal lectin-mediated drug delivery.

  2004cites this paper
• Differential response to keratinocyte growth factor receptor and epidermal growth factor receptor ligands of proliferating and differentiating intestinal epithelial cells

  2004cites this paper
• Epidermal growth factor and insulin short-term increase hPepT1-mediated glycylsarcosine uptake in Caco-2 cells.

  2003cites this paper
• Wheat Germ Agglutinin Binds to the Epidermal Growth Factor Receptor of Artificial Caco-2 Membranes as Detected by Silver Nanoparticle Enhanced Fluorescence

  2003influential citation
• Effect of excipients on the stability and transport of recombinant human epidermal growth factor (rhEGF) across CACO-2 cell monolayers

  2003cites this paper
• Absorption and Drug Development: Solubility, Permeability, and Charge State

  2003cites this paper
• Permeability characteristics of polyamines across intestinal epithelium using the Caco-2 monolayer system: comparison between transepithelial flux and mitogen-stimulated uptake into epithelial cells.

  2001cites this paper
• Apical and basolateral EGF receptors regulate gastric mucosal paracellular permeability.

  2001cites this paper
• Transepithelial transport of putrescine across monolayers of the human intestinal epithelial cell line, Caco-2.

  2001cites this paper
• Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line.

  2001cites this paper
• Physicochemical profiling (solubility, permeability and charge state).

  2001cites this paper
• Physicochemical Profiling (Solubility, Permeability and Charge State)

  2001cites this paper
• Integrin alpha5/beta1 mediates fibronectin-dependent epithelial cell proliferation through epidermal growth factor receptor activation.

  2000cites this paper
• Nonsteroidal anti-inflammatory drugs attenuate proliferation of colonic carcinoma cells by blocking epidermal growth factor-induced Ca++ mobilization

  2000cites this paper
• EGF-Stimulated Polyamine Accumulation in the Colon Carcinoma Cell Line, Caco-2

  2000cites this paper
• Integrin α5/β1 Mediates Fibronectin-dependent Epithelial Cell Proliferation through Epidermal Growth Factor Receptor Activation

  2000cites this paper
• Epidermal growth factor-induced cytoprotection in human intestinal cells involves intracellular calcium signaling.

  2000cites this paper
• Epidermal growth factor regulates fatty acid uptake and metabolism in Caco-2 cells.

  1999cites this paper
• The dynamic expression of the epidermal growth factor receptor and epidermal growth factor ligand family in a differentiating intestinal epithelial cell line.

  1999cites this paper
• Epidermal growth factor regulates fatty acid uptake and metabolism in Caco-2 cells.

  1999cites this paper
• Ontogeny of EGF receptors in the human gut.

  1999cites this paper
• AGI Mar 39/3

  1999cites this paper
• Mechanism of antimitogenic action of vitamin D in human colon carcinoma cells: relevance for suppression of epidermal growth factor-stimulated cell growth.

  1999cites this paper
• S-adenosylmethionine decarboxylase activity and utilization of exogenous putrescine are enhanced in colon cancer cells stimulated to grow by EGF.

  1998cites this paper
• Epidermal growth factor receptor expression in primary cultured human colorectal carcinoma cells.

  1998influential citation
• The effect of apotransferrin on iron release from Caco-2 cells, an intestinal epithelial cell line.

  1998cites this paper
• Human Insulin Diffusion Profile Through a Layer of Caco-2 Cells

  1997cites this paper
• Immobilized Artificial Membranes — screens for drug membrane interactions

  1997cites this paper
• Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation.

  1997cites this paper
• A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model.

  1997cites this paper
• Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation.

  1997cites this paper
• Epidermal growth factor up-regulates sodium-glucose cotransport in enterocyte models in the presence of cholera toxin.

  1997cites this paper
• Effect of methotrexate and 5-fluorouracil on de novo thymidylate synthesis in human colon carcinoma cell line, Caco-2

  1996cites this paper
• Insulin receptor tyrosine kinase activity in colon carcinoma.

  1996cites this paper
• Expression of insulin-like growth factor (IGF)-I receptors, IGF-II/cation-independent mannose 6-phosphate receptors (CI-MPRs), and cation-dependent MPRs in polarized human intestinal Caco-2 cells.

  1996cites this paper
• The Influence of Polarized Epithelial (Caco-2) Cell Differentiation on the Cellular Binding of Phosphodiester and Phosphorothioate Oligonucleotides

  1996cites this paper
• Epidermal growth factor (EGF).

  1996cites this paper
• Development of intestinal cell culture models for drug transport and metabolism studies

  1996cites this paper
• Protein kinase C-dependent regulation of L-arginine transport activity in Caco-2 intestinal cells.

  1995cites this paper
• Interruption of a transforming growth factor alpha autocrine loop in Caco-2 cells by antisense oligodeoxynucleotides.

  1995cites this paper
• Diffusion Profile of Human Insulin Through Polycarbonate Membrane

  1995cites this paper
• EGF stimulates polyamine uptake in Caco-2 cells.

  1995cites this paper
• In vitro systems for studying intestinal drug absorption

  1995cites this paper
• Differentiation and Polarity Alter the Binding of IGF‐I to Human Intestinal Epithelial (Caco‐2) Cells

  1995cites this paper
• Surface distribution of the EGF receptor during differentiation of the human colon carcinoma cell line HT29-D4.

  1994cites this paper
• Regulation of Caco-2 cell proliferation by basolateral membrane epidermal growth factor receptors.

  1994cites this paper
• Proliferation and differentiation of the small intestinal epithelium: from Petri dish to bedside.

  1994cites this paper
• Profile of IGF-binding proteins secreted by intestinal epithelial cells changes with differentiation.

  1994cites this paper
• Metabolism of L-alpha-methyldopa in cultured human intestinal epithelial (Caco-2) cell monolayers. Comparison with metabolism in vivo.

  1994cites this paper
• Epidermal growth factor induces protein tyrosine phosphorylation and association of p190 with ras‐GTP‐ase activating protein in Caco‐2 cells

  1994cites this paper
• Diamine oxidase in relation to diamine and polyamine metabolism

  1994cites this paper
• Transport mechanisms responsible for the absorption of loracarbef, cefixime, and cefuroxime axetil into human intestinal Caco-2 cells.

  1994cites this paper
• Cytokine modulation of Na(+)-dependent glutamine transport across the brush border membrane of monolayers of human intestinal Caco-2 cells.

  1992cites this paper
• Constitutive secretion of a bacterial enzyme by polarized epithelial cells.

  1992cites this paper
• [Growth factors and intestinal cancers].

  1992cites this paper
• Interleukin-4 receptor and epidermal growth factor receptor expression in colorectal cancer.

  1992cites this paper
• Kinetics of the sodium-dependent glutamine transporter in human intestinal cell confluent monolayers.

  1992cites this paper
• Iron absorption by intestinal epithelial cells: 1. CaCo2 cells cultivated in serum-free medium, on polyethyleneterephthalate microporous membranes, as an in vitro model

  1991cites this paper
• Pharmaceutical Applications of Cell Culture: An Overview

  1991cites this paper
• Effects of epidermal growth factor on diamine oxidase expression and cell growth in Caco-2 cells.

  1991cites this paper
• Expression of cobalamin transport proteins and cobalamin transcytosis by colon adenocarcinoma cells.

  1991cites this paper
• Growth factor signal transduction in human intestinal cells.

  1991cites this paper
• GROWTH AND CHARACTERIZATION OF CELL AND TISSUE CULTURES FOR THE STUDY OF DRUG TRANSPORT

  1991cites this paper
• Inhibition of sucrose-isomaltase expression by EGF in the human colon adenocarcinoma cells Caco-2.

  1991cites this paper
• Substrate specificity and some properties of phenol sulfotransferase from human intestinal Caco-2 cells.

  1991cites this paper
• Transcytosis of epidermal growth factor. The epidermal growth factor receptor mediates uptake but not transcytosis.

  1991cites this paper
• Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2.

  1990cites this paper
• Assessment of transport barriers using cell and tissue culture systems

  1990cites this paper
• Increased cell surface EGF receptor expression during the butyrate-induced differentiation of human HCT-116 colon tumor cell clones.

  1990cites this paper
• The Use of Cultured Epithelial and Endothelial Cells for Drug Transport and Metabolism Studies

  1990cites this paper
• Cell culture techniques for the study of drug transport

  1990cites this paper
• Basolateral secretion of kappa light chain in the polarised epithelial cell line, Caco-2.

  1989cites this paper