Purine-rich enhancers function in the AT-AC pre-mRNA splicing pathway and do so independently of intact U1 snRNP.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  RNA: A publication of the RNA Society

• Publication date

  1998-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1017/S1355838298981432PMID 9848661PMCID PMC1369733
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• SR proteins are sufficient for exon bridging across an intron.

  1998cited by this paper
• Base pairing with U6atac snRNA is required for 5' splice site activation of U12-dependent introns in vivo.

  1998cited by this paper
• RNA-RNA Interactions in Nuclear Pre-mRNA Splicing

  1998influential reference
• Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins.

  1998cited by this paper
• Identification of a new class of exonic splicing enhancers by in vivo selection

  1997cited by this paper
• Site-specific crosslinking of mammalian U11 and u6atac to the 5' splice site of an AT-AC intron.

  1997cited by this paper
• Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs.

  1997influential reference
• U11 snRNA interacts in vivo with the 5' splice site of U12-dependent (AU-AC) pre-mRNA introns.

  1997cited by this paper
• Classification of introns: U2-type or U12-type.

  1997cited by this paper
• Common themes in the function of transcription and splicing enhancers.

  1997cited by this paper
• Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge.

  1997cited by this paper
• U1 snRNA promotes the selection of nearby 5' splice sites by U6 snRNA in mammalian cells.

  1996cited by this paper
• A Parallel Spliceosome

  1996cited by this paper
• An intron enhancer recognized by splicing factors activates polyadenylation.

  1996cited by this paper
• A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro.

  1996influential reference
• Factors involved in the activation of pre-mRNA splicing from downstream splicing enhancers.

  1996influential reference
• The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.

  1996cited by this paper
• Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA [corrected].

  1996cited by this paper
• Highly Diverged U4 and U6 Small Nuclear RNAs Required for Splicing Rare AT-AC Introns

  1996influential reference
• A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer.

  1996cited by this paper
• SR proteins and splicing control.

  1996cited by this paper
• U1-Mediated Exon Definition Interactions Between AT-AC and GT-AG Introns

  1996influential reference
• Interactions among SR proteins, an exonic splicing enhancer, and a lentivirus Rev protein regulate alternative splicing

  1996cited by this paper
• Interaction of U2AF65 RS Region with Pre-mRNA of Branch Point and Promotion Base Pairing with U2 snRNA

  1996cited by this paper
• Requirement of U12 snRNA for in Vivo Splicing of a Minor Class of Eukaryotic Nuclear Pre-mRNA Introns

  1996cited by this paper
• Intrinsic U2AF binding is modulated by exon enhancer signals in parallel with changes in splicing activity.

  1995cited by this paper
• Enhancer-dependent interaction between 5' and 3' splice sites in trans.

  1995cited by this paper
• Synergistic interactions between two distinct elements of a regulated splicing enhancer.

  1995cited by this paper
• A two-step mechanism for 5' and 3' splice-site pairing

  1995cited by this paper
• The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities.

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• A U6 snRNA:pre-mRNA interaction can be rate-limiting for U1-independent splicing.

  1995cited by this paper
• Identification of positive and negative splicing regulatory elements within the terminal tat-rev exon of human immunodeficiency virus type 1

  1995cited by this paper
• Selection of novel exon recognition elements from a pool of random sequences

  1995cited by this paper
• Distinct functions of SR proteins in recruitment of U1 small nuclear ribonucleoprotein to alternative 5' splice sites.

  1995cited by this paper
• Exon Recognition in Vertebrate Splicing (*)

  1995influential reference
• Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors

  1995cited by this paper
• Presence of exon splicing silencers within human immunodeficiency virus type 1 tat exon 2 and tat-rev exon 3: evidence for inhibition mediated by cellular factors.

  1995cited by this paper
• Finding splice sites within a wilderness of RNA.

  1995cited by this paper
• Complementation by SR proteins of pre-mRNA splicing reactions depleted of U1 snRNP.

  1994cited by this paper
• SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex

  1994influential reference
• Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

  1994cited by this paper
• Conserved sequences in a class of rare eukaryotic nuclear introns with non-consensus splice sites.

  1994cited by this paper
• Sequences homologous to 5' splice sites are required for the inhibitory activity of papillomavirus late 3' untranslated regions

  1994cited by this paper
• Polypurine sequences within a downstream exon function as a splicing enhancer

  1994cited by this paper
• A splicing enhancer exhibits both constitutive and regulated activities.

  1994cited by this paper
• SR proteins can compensate for the loss of U1 snRNP functions in vitro.

  1994cited by this paper
• Association with terminal exons in pre-mRNAs: a new role for the U1 snRNP?

  1993cited by this paper
• General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer.

  1993cited by this paper
• A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.

  1993cited by this paper
• A base-pairing interaction between U2 and U6 small nuclear RNAs occurs in > 150S complexes in HeLa cell extracts: implications for the spliceosome assembly pathway.

  1993cited by this paper
• Pathways for selection of 5′ splice sites by U1 snRNPs and SF2/ASF.

  1993cited by this paper
• Control of calcitonin/calcitonin gene-related peptide pre-mRNA processing by constitutive intron and exon elements

  1993cited by this paper
• Uncoupling two functions of the U1 small nuclear ribonucleoprotein particle during in vitro splicing

  1993influential reference
• The role of exon sequences in splice site selection.

  1993cited by this paper
• Mutations which alter splicing in the human hypoxanthine-guanine phosphoribosyltransferase gene.

  1992cited by this paper
• Control of alternative splicing by the differential binding of U1 small nuclear ribonucleoprotein particle.

  1991cited by this paper
• A reappraisal of non-consensus mRNA splice sites.

  1991cited by this paper
• The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA.

  1991cited by this paper
• Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly.

  1990cited by this paper
• Control of retroviral RNA splicing through maintenance of suboptimal processing signals

  1990cited by this paper
• Exon definition may facilitate splice site selection in RNAs with multiple exons.

  1990cited by this paper
• Spliced leader RNA sequences can substitute for the essential 5' end of U1 RNA during splicing in a mammalian in vitro system.

  1990cited by this paper
• Alternative splicing of tropomyosin pre-mRNAs in vitro and in vivo.

  1988cited by this paper
• Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes.

  1987cited by this paper
• A role for exon sequences in alternative splicing of the human fibronectin gene.

  1987cited by this paper
• Are snRNPs involved in splicing?

  1980cited by this paper
• [Leadership through Motivation in the health sectors: greater satisfaction can be achieved through personnel development].

  1976cited by this paper
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