Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6–24 weeks

The data presented in this article describe the fatty acid composition of chow, liver tissue and isolated liver mitochondria from mice fed for 6–24 weeks with a high caloric western diet (WD) in comparison to control diet (normal diet, ND). The fatty acid composition was measured via gas chromatography flame ionization detection (GC-FID). Moreover, WD-induced mitochondrial protein changes are presented in this work and were analyzed by mass spectrometry (LC–MS/MS). For further interpretation and discussion of the presented data please refer to the research article entitled “Mitochondrial adaptation in steatotic mice” (Einer et al., 2017) [1].

• Publication year

  2017

• Venue

  Data in Brief

• Publication date

  2017-09-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.dib.2017.09.019PMID 29034285PMCID 5633826
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mitochondrial adaptation in steatotic mice.

  2017cited by this paper
• KEGG as a reference resource for gene and protein annotation

  2015cited by this paper
• A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain.

  2015cited by this paper
• Why to compare absolute numbers of mitochondria.

  2014cited by this paper
• UniProt: a hub for protein information

  2014cited by this paper
• Apoe, Mbl2, and Psp plasma protein levels correlate with diabetic phenotype in NZO mice--an optimized rapid workflow for SRM-based quantification.

  2013cited by this paper
• Deciphering Membrane-Associated Molecular Processes in Target Tissue of Autoimmune Uveitis by Label-Free Quantitative Mass Spectrometry*

  2010cited by this paper
• Universal sample preparation method for proteome analysis

  2009cited by this paper
• Universal sample preparation method for proteome analysis

  2009cited by this paper
• Severe NAFLD with hepatic necroinflammatory changes in mice fed trans fats and a high-fructose corn syrup equivalent.

  2008cited by this paper
• PANTHER: a library of protein families and subfamilies indexed by function.

  2003cited by this paper
• A simple method for the isolation and purification of total lipides from animal tissues.

  1957cited by this paper

• The proteomic fingerprint in infants with single ventricle heart disease in the interstage period: evidence of chronic inflammation and widespread activation of biological networks

  2023cites this paper
• Brassica oleracea Var italica by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity

  2023cites this paper
• Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2.

  2022cites this paper
• Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells

  2021cites this paper
• Potential evidence for epigenetic biomarkers of metabolic syndrome in human whole blood in Latinos

  2021cites this paper
• Significance of Simple Steatosis: An Update on the Clinical and Molecular Evidence

  2020cites this paper
• IL-18 But Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease

  2020cites this paper
• Fat and Sugar—A Dangerous Duet. A Comparative Review on Metabolic Remodeling in Rodent Models of Nonalcoholic Fatty Liver Disease

  2019cites this paper
• A High-Calorie Diet Aggravates Mitochondrial Dysfunction and Triggers Severe Liver Damage in Wilson Disease Rats

  2018influential citation
• Mitochondrial adaptation in steatotic mice.

  2017cites this paper