Vascular Adhesion Protein-1 Inhibition Provides Antiinflammatory Protection after an Intracerebral Hemorrhagic Stroke in Mice

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Journal of Cerebral Blood Flow and Metabolism

• Publication date

  2011-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/jcbfm.2010.167PMID 20877383PMCID PMC3063621
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Ac-YVAD-CMK Decreases Blood–Brain Barrier Degradation by Inhibiting Caspase-1 Activation of Interleukin-1β in Intracerebral Hemorrhage Mouse Model

  2010cited by this paper
• Heme oxygenase 2 deficiency increases brain swelling and inflammation after intracerebral hemorrhage.

  2008cited by this paper
• The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole blood.

  2008cited by this paper
• Anti-Inflammatory Effects of LJP 1586 [Z-3-Fluoro-2-(4-methoxybenzyl)allylamine Hydrochloride], an Amine-Based Inhibitor of Semicarbazide-Sensitive Amine Oxidase Activity

  2008cited by this paper
• HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model.

  2008cited by this paper
• Reduced brain injury in CD18‐deficient mice after experimental intracerebral hemorrhage

  2008cited by this paper
• Preclinical Models of Intracerebral Hemorrhage: A Translational Perspective

  2008cited by this paper
• Vascular adhesion protein‐1 in human ischaemic stroke

  2008cited by this paper
• Cell adhesion molecules and ischemic stroke

  2008influential reference
• Vascular adhesion protein‐1 blockade suppresses choroidal neovascularization

  2008influential reference
• Intracerebral Hemorrhage Models in Rat: Comparing Collagenase to Blood Infusion

  2008cited by this paper
• A mouse model of intracerebral hemorrhage using autologous blood infusion

  2008cited by this paper
• Inflammation after Intracerebral Hemorrhage

  2007cited by this paper
• Modifications of Arterial Phenotype in Response to Amine Oxidase Inhibition by Semicarbazide

  2007cited by this paper
• Astrocytic Induction of Matrix Metalloproteinase-9 and Edema in Brain Hemorrhage

  2007cited by this paper
• Increased Tolerance to Ischemic Neuronal Damage by Knockdown of Na+–Ca2+ Exchanger Isoform 1

  2007cited by this paper
• The oxidase activity of vascular adhesion protein-1 (VAP-1) induces endothelial E- and P-selectins and leukocyte binding.

  2007influential reference
• Vascular Adhesion Protein-1 Plays an Important Role in Postischemic Inflammation and Neuropathology in Diabetic, Estrogen-Treated Ovariectomized Female Rats Subjected to Transient Forebrain Ischemia

  2006cited by this paper
• Latest advances in intracerebral hemorrhage

  2006cited by this paper
• Role of NADPH oxidase in the brain injury of intracerebral hemorrhage

  2005cited by this paper
• Mechanisms of Hyperbaric Oxygen-Induced Neuroprotection in a Rat Model of Subarachnoid Hemorrhage

  2005cited by this paper
• Absence of the endothelial oxidase AOC3 leads to abnormal leukocyte traffic in vivo.

  2005cited by this paper
• New Horizons for Primary Intracerebral Hemorrhage Treatment: Experience From Preclinical Studies

  2005cited by this paper
• Cell-surface enzymes in control of leukocyte trafficking

  2005cited by this paper
• MMP-9 Deficiency Enhances Collagenase-Induced Intracerebral Hemorrhage and Brain Injury in Mutant Mice

  2004cited by this paper
• Experimental intracerebral hemorrhage in the mouse: histological, behavioral, and hemodynamic characterization of a double-injection model.

  2003cited by this paper
• Inflammation and Infection in Clinical Stroke

  2002cited by this paper
• A cell surface amine oxidase directly controls lymphocyte migration.

  2001cited by this paper
• Evidence for Apoptosis After Intracerebral Hemorrhage in Rat Striatum

  2000cited by this paper
• Transient focal cerebral ischemia induces sensorimotor deficits in mice.

  2000cited by this paper
• Neurological impairment in rats after transient middle cerebral artery occlusion: a comparative study under various treatment paradigms.

  2000cited by this paper
• Inflammatory Mediators and Stroke: New Opportunities for Novel Therapeutics

  1999cited by this paper
• Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation.

  1995cited by this paper
• Bacterial collagenase disrupts extracellular matrix and opens blood-brain barrier in rat.

  1993cited by this paper
• Long‐term Survival After First‐Ever Stroke: The Oxfordshire Community Stroke Project

  1993cited by this paper
• A 90-kilodalton endothelial cell molecule mediating lymphocyte binding in humans.

  1992cited by this paper
• Collagenase-induced intracerebral hemorrhage in rats.

  1990cited by this paper
• Hemostasis, Thrombosis, and Vascular Biology Table 1. Inhibition of Vap-1/ssao and Total Mao Enzyme Activity by Hydroxylamine, Semicarbazide, and Btt-2027

  year unknowncited by this paper

• Intracerebral Hemorrhage: Advances, Knowledge Gaps, and Future Directions

  2025cites this paper
• Vascular-adhesion protein 1 in giant cell arteritis and polymyalgia rheumatica

  2024cites this paper
• Mechanism and application of immune interventions in intracerebral haemorrhage

  2024cites this paper
• Emerging diagnostic markers and therapeutic targets in post-stroke hemorrhagic transformation and brain edema

  2023cites this paper
• Caudal DMN neurons innervate the spleen and release CART peptide to regulate neuroimmune function

  2023cites this paper
• Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases.

  2022cites this paper
• Curcumin regulates glial cell polarization through TLR4/NF-κB pathway after intracerebral hemorrhage

  2022cites this paper
• Lipoxin A4 Receptor Stimulation Attenuates Neuroinflammation in a Mouse Model of Intracerebral Hemorrhage

  2022cites this paper
• Establishment of composite experimental animal model of brain edema after cerebral hemorrhagic.

  2021cites this paper
• SSAO/VAP-1 in Cerebrovascular Disorders: A Potential Therapeutic Target for Stroke and Alzheimer’s Disease

  2021cites this paper
• Inhibition of Vascular Adhesion Protein 1 Protects Dopamine Neurons From the Effects of Acute In�ammation and Restores Habit Learning in the Striatum

  2021cites this paper
• Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine

  2021cites this paper
• Role of Monoamine Oxidase Activity in Alzheimer’s Disease: An Insight into the Therapeutic Potential of Inhibitors

  2021cites this paper
• Vascular Adhesion Protein-1 (VAP-1)/Semicarbazide-Sensitive Amine Oxidase (SSAO): A Potential Therapeutic Target for Atherosclerotic Cardiovascular Diseases

  2021cites this paper
• Microglia in the Pathophysiology of Hemorrhagic Stroke and the Relationship Between Microglia and Pain After Stroke: A Narrative Review

  2021cites this paper
• Assessing the Evolution of Intracranial Hematomas by using Animal Models: A Review of the Progress and the Challenges

  2021cites this paper
• Inhibition of vascular adhesion protein 1 protects dopamine neurons from the effects of acute inflammation and restores habit learning in the striatum

  2021cites this paper
• Vascular adhesion protein-1 defines a unique subpopulation of human hematopoietic stem cells and regulates their proliferation

  2021cites this paper
• Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology, and Cognitive Impairments.

  2021cites this paper
• Progress on siRNA-based gene therapy targeting secondary injury after intracerebral hemorrhage

  2021cites this paper
• Effect of Acupuncture on the Expression of Heme Oxygenase 1 and Inflammatory Factors in Rats with Intracerebral Hemorrhage

  2021cites this paper
• Increased Vascular Adhesion Protein 1 (VAP-1) Levels Are Associated with Alternative M2 Macrophage Activation and Poor Prognosis for Human Gliomas

  2020cites this paper
• MicroRNA-152 attenuates neuroinflammation in intracerebral hemorrhage by inhibiting thioredoxin interacting protein (TXNIP)-mediated NLRP3 inflammasome activation.

  2020cites this paper
• Human Copper-Containing Amine Oxidases in Drug Design and Development

  2020cites this paper
• Programmed Cell Deaths and Potential Crosstalk With Blood–Brain Barrier Dysfunction After Hemorrhagic Stroke

  2020cites this paper
• Incremental Accuracy of Blood Biomarkers for Predicting Clinical Outcomes After Intracerebral Hemorrhage.

  2020cites this paper
• IGF-1R stimulation alters microglial polarization via TLR4/NF-κB pathway after cerebral hemorrhage in mice.

  2020cites this paper
• The expression of cerebrospinal fluid pentraxin-3 in patients with hemorrhagic stroke

  2019cites this paper
• Comparison of the diagnostic values of vascular adhesion protein-1 and intestinal fatty acid-binding protein in the diagnosis of acute mesenteric ischemia

  2019cites this paper
• rhIGF‐1 reduces the permeability of the blood‐brain barrier following intracerebral hemorrhage in mice

  2019cites this paper
• Inhibition of Semicarbazide-sensitive Amine Oxidase Reduces Atherosclerosis in Cholesterol-fed New Zealand White Rabbits

  2018cites this paper
• Efficacy of a novel inhibitor of vascular adhesion protein-1 in reducing albuminuria in patients with diabetic kidney disease (ALBUM): a randomised, placebo-controlled, phase 2 trial.

  2018cites this paper
• HSP-70-Mediated Hyperbaric Oxygen Reduces Brain and Pulmonary Edema and Cognitive Deficits in Rats in a Simulated High-Altitude Exposure

  2018cites this paper
• Increased Expression of T Cell Immunoglobulin and Mucin Domain 3 on CD14+ Monocytes Is Associated with Systemic Inflammatory Reaction and Brain Injury in Patients with Spontaneous Intracerebral Hemorrhage.

  2018cites this paper
• Inhibition of semicarbazide‐sensitive amine oxidase reduces atherosclerosis in apolipoprotein E‐deficient mice

  2018cites this paper
• Angiopoietin-Like 4 Attenuates Brain Edema and Neurological Deficits in a Mouse Model of Experimental Intracerebral Hemorrhage

  2018cites this paper
• Are Plasma Levels of Vascular Adhesion Protein-1 Associated Both with Cerebral Microbleeds in Multiple Sclerosis and Intracerebral Haemorrhages in Stroke?

  2018cites this paper
• Macrophage stimulating protein preserves blood brain barrier integrity after intracerebral hemorrhage through recepteur d'origine nantais dependent GAB1/Src/β‐catenin pathway activation in a mouse model

  2018cites this paper
• Simvastatin blocks soluble SSAO/VAP-1 release in experimental models of cerebral ischemia: Possible benefits for stroke-induced inflammation control.

  2018cites this paper
• Therapeutic Potential of Drugs Targeting Pathophysiology of Intracerebral Hemorrhage: From Animal Models to Clinical Applications.

  2017cites this paper
• Injury mechanisms in acute intracerebral hemorrhage

  2017cites this paper
• Neuroprotective Strategies in Hemorrhagic Stroke

  2017cites this paper
• Vascular Adhesion Protein-1: A Cell Surface Amine Oxidase in Translation

  2017cites this paper
• Hypoxia serves a key function in the upregulated expression of vascular adhesion protein-1 in vitro and in a rat model of hemorrhagic shock

  2017cites this paper
• C1q/tumor necrosis factor-related protein 3 inhibits oxidative stress during intracerebral hemorrhage via PKA signaling.

  2017cites this paper
• Fucoidan from Fucus vesiculosus Fails to Improve Outcomes Following Intracerebral Hemorrhage in Mice.

  2016cites this paper
• von Willebrand factor contributes to poor outcome in a mouse model of intracerebral haemorrhage

  2016cites this paper
• Stages of the Inflammatory Response in Pathology and Tissue Repair after Intracerebral Hemorrhage

  2016cites this paper
• Up-Regulation of Interferon Regulatory Factor 3 Involves in Neuronal Apoptosis After Intracerebral Hemorrhage in Adult Rats

  2016cites this paper
• Phosphoinositide 3-Kinase Gamma Contributes to Neuroinflammation in a Rat Model of Surgical Brain Injury

  2015cites this paper
• Vascular adhesion protein-1: Role in human pathology and application as a biomarker

  2015cites this paper
• VAP-1 blockade prevents subarachnoid hemorrhage-associated cerebrovascular dilating dysfunction via repression of a neutrophil recruitment-related mechanism.

  2015cites this paper
• Brain Targeting of siRNA via Intranasal Pathway.

  2015cites this paper
• Neuronal tumour necrosis factor-α and interleukin-1β expression in a porcine model of intracerebral haemorrhage: Modulation by U-74389G.

  2015cites this paper
• Study of the role of SSAO/VAP-1 in OGD conditions using SSAO/VAP-1-expressing HUVEC and human brain endothelial cells (hCMEC/D3) as experimental models of ischemic stroke, and its possible nexus with Alzheimer´s disease

  2015cites this paper
• Novel Inflammatory Biomarkers in Cardiovascular Therapeutics.

  2015cites this paper
• Intercellular cross-talk in intracerebral hemorrhage.

  2015cites this paper
• Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage.

  2015cites this paper
• Neuroinflammation after intracerebral hemorrhage

  2014cites this paper
• &agr;4 Integrin Is a Regulator of Leukocyte Recruitment After Experimental Intracerebral Hemorrhage

  2014cites this paper
• Potential Role of Blood Biomarkers in the Management of Nontraumatic Intracerebral Hemorrhage

  2014cites this paper
• Vascular disruption and blood–brain barrier dysfunction in intracerebral hemorrhage

  2014cites this paper
• Correlation between subacute sensorimotor deficits and brain edema in two mouse models of intracerebral hemorrhage.

  2014cites this paper
• Inflammation in intracerebral hemorrhage: from mechanisms to clinical translation.

  2014cites this paper
• Pharmacologic blockade of vascular adhesion protein-1 lessens neurologic dysfunction in rats subjected to subarachnoid hemorrhage.

  2014cites this paper
• Controversies and evolving new mechanisms in subarachnoid hemorrhage.

  2014cites this paper
• Stroke Pathophysiology and Reactive Oxygen Species

  2014cites this paper
• Novel siRNA delivery strategy: a new “strand” in CNS translational medicine?

  2013cites this paper
• Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage.

  2013cites this paper
• Hydrogen Inhalation Ameliorated Mast Cell–Mediated Brain Injury After Intracerebral Hemorrhage in Mice

  2013cites this paper
• Erythropoietin reduces brain injury after intracerebral hemorrhagic stroke in rats.

  2013cites this paper
• PAR-1 antagonist SCH79797 ameliorates apoptosis following surgical brain injury through inhibition of ASK1-JNK in rats.

  2013cites this paper
• MyD88 Is a Critical Regulator of Hematopoietic Cell-Mediated Neuroprotection Seen after Stroke

  2013cites this paper
• siRNA Treatment: “A Sword-in-the-Stone” for Acute Brain Injuries

  2013influential citation
• Adhesion molecules in CNS disorders: biomarker and therapeutic targets.

  2013cites this paper
• Protective Effects of Urinary Trypsin Inhibitor on Vascular Permeability Following Subarachnoid Hemorrhage in a Rat Model

  2013cites this paper
• High‐mobility group box 1 from reactive astrocytes enhances the accumulation of endothelial progenitor cells in damaged white matter

  2013cites this paper
• Sleep a therapeutic target for stroke?

  2012cites this paper
• &agr;7 Nicotinic Acetylcholine Receptor Agonism Confers Neuroprotection Through GSK-3&bgr; Inhibition in a Mouse Model of Intracerebral Hemorrhage

  2012cites this paper
• Intracerebral haemorrhage: mechanisms of injury and therapeutic targets.

  2012cites this paper
• The CCL2‐CCR2 system affects the progression and clearance of intracerebral hemorrhage

  2012cites this paper
• Modeling intracerebral hemorrhage in mice: injection of autologous blood or bacterial collagenase.

  2012cites this paper
• Fibroblast growth factors preserve blood-brain barrier integrity through RhoA inhibition after intracerebral hemorrhage in mice.

  2012cites this paper
• Post‐ischemic vascular adhesion protein‐1 inhibition provides neuroprotection in a rat temporary middle cerebral artery occlusion model

  2012influential citation
• Targeting C/EBP homologous protein with siRNA attenuates cerebral vasospasm after experimental subarachnoid hemorrhage.

  2012cites this paper
• Depletion of GR-1-Positive Cells Is Associated with Reduced Neutrophil Inflammation and Astrocyte Reactivity after Experimental Intracerebral Hemorrhage

  2012cites this paper
• Blockade of vascular adhesion protein-1 attenuates choroidal neovascularization

  2012cites this paper
• Leukocyte trafficking: a special focus on VAP-1 and CLEVER-1

  2012cites this paper
• Plasmalemma Permeability and Necrotic Cell Death Phenotypes After Intracerebral Hemorrhage in Mice

  2012cites this paper
• Comparison of humoral neuroinflammation and adhesion molecule expression in two models of experimental intracerebral hemorrhage

  2011cites this paper
• HIV-1 Tat-Induced Microgliosis and Synaptic Damage via Interactions between Peripheral and Central Myeloid Cells

  2011cites this paper
• The association between serum adhesion molecules and outcome in acute spontaneous intracerebral hemorrhage

  2011cites this paper
• VAP-1/SSAO Plasma Activity and Brain Expression in Human Hemorrhagic Stroke

  2011cites this paper