D2-40, a novel monoclonal antibody against the M2A antigen as a marker to distinguish hemangioblastomas from renal cell carcinomas

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Acta Neuropathologica

• Publication date

  2005-04-27

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00401-005-0999-3PMID 15864611
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2003influential reference
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• Monoclonal Antibody D2-40, a New Marker of Lymphatic Endothelium, Reacts with Kaposi's Sarcoma and a Subset of Angiosarcomas

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• Hemangioblastomas of the Central Nervous System in von Hippel-Lindau Syndrome and Sporadic Disease

  2001influential reference
• Clear Cell Carcinoma of the Liver: A Comparative Immunohistochemical Study with Renal Clear Cell Carcinoma

  2000cited by this paper
• Transthyretin and transferrin in hemangioblastoma stromal cells.

  2000cited by this paper
• Angiogenic histogenesis of stromal cells in hemangioblastoma: ultrastructural and immunohistochemical study.

  1999cited by this paper
• Metastatic renal cell carcinoma to the bladder: a clinicopathologic and immunohistochemical study.

  1999cited by this paper
• Metastasis of renal carcinoma to a cerebellar hemangioblastoma in a patient with von Hippel Lindau disease: a case report.

  1999cited by this paper
• Hormone receptor immunoreactivity in hemangioblastomas and clear cell renal cell carcinomas.

  1998cited by this paper
• Immunohistochemical and ultrastructural studies of stromal cells in hemangioblastoma.

  1995cited by this paper
• Immunohistochemical staining of germ cell tumors and intratubular malignant germ cells of the testis using antibody to placental alkaline phosphatase and a monoclonal anti-seminoma antibody.

  1991cited by this paper
• Surgical pathology of the nervous system and its coverings

  1991cited by this paper
• A detailed immunohistochemical analysis of cerebellar hemangioblastoma: an undifferentiated mesenchymal tumor.

  1989cited by this paper
• Use of immunohistochemical methods in the differential diagnosis between primary cerebellar haemangioblastoma and metastatic renal carcinoma.

  1988cited by this paper
• Selective localization of gamma-enolase in stromal cells of cerebellar hemangioblastomas.

  1987cited by this paper
• Immunoperoxidase labelled antibody staining in differential diagnosis of central nervous system haemangioblastomas and central nervous system metastases of renal carcinomas.

  1986cited by this paper
• Production of a monoclonal antibody specific for seminomas and dysgerminomas.

  1986cited by this paper
• Histogenesis of haemangioblastomas: an immunocytochemical and ultrastructural study in a case of von Hippel-Lindau syndrome.

  1985cited by this paper
• Surgical Pathology of the Nervous System and its Coverings

  1976cited by this paper
• ©1999 Cancer Research Campaign Article no. bjoc.1998.0393

  year unknowninfluential reference

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