Paeoniflorin Upregulates β-Defensin-2 Expression in Human Bronchial Epithelial Cell Through the p38 MAPK, ERK, and NF-κB Signaling Pathways

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Inflammation

• Publication date

  2014-04-04

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s10753-014-9872-7PMID 24700312
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Induction of human defensins by intestinal Caco-2 cells after interactions with opportunistic Candida species.

  2014cited by this paper
• Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway.

  2014cited by this paper
• A Novel Lipopeptide from Skin Commensal Activates TLR2/CD36-p38 MAPK Signaling to Increase Antibacterial Defense against Bacterial Infection

  2013cited by this paper
• [Advance in studies on effect of paeoniflorin on nervous system].

  2013cited by this paper
• Pneumolysin-mediated expression of β-defensin 2 is coordinated by p38 MAP kinase-MKP1 in human airway cells

  2013cited by this paper
• Paeoniflorin, a monoterpene glycoside, attenuates lipopolysaccharide-induced neuronal injury and brain microglial inflammatory response

  2013cited by this paper
• Pseudomonas fluorescens can induce and divert the human β-defensin-2 secretion in intestinal epithelial cells to enhance its virulence

  2013cited by this paper
• The induction expression of human β-defensins in gingival epithelial cells and fibroblasts.

  2013cited by this paper
• Paeoniflorin inhibits inflammatory responses in mice with allergic contact dermatitis by regulating the balance between inflammatory and anti-inflammatory cytokines

  2013cited by this paper
• MAP kinase signalling cascades and transcriptional regulation.

  2013cited by this paper
• Streptococcus pneumoniae induces human β-defensin-2 and -3 in human lung epithelium

  2012cited by this paper
• Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis.

  2012cited by this paper
• Extracellular HIV-1 Tat induces human beta-defensin-2 production via NF-kappaB/AP-1 dependent pathways in human B cells

  2012cited by this paper
• Protective effect of a molecular chaperone inducer, paeoniflorin, on the HCl- and ethanol-triggered gastric mucosal injury.

  2011cited by this paper
• Paeoniflorin improves survival in LPS-challenged mice through the suppression of TNF-α and IL-1β release and augmentation of IL-10 production.

  2011cited by this paper
• Innate Immunity and the Role of Defensins in Otitis Media

  2011cited by this paper
• Pattern recognition receptors and inflammation.

  2010cited by this paper
• Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections.

  2010cited by this paper
• Epithelial cell-derived antimicrobial peptides are multifunctional agents that bridge innate and adaptive immunity.

  2010cited by this paper
• Review: Defensins and cathelicidins in lung immunity

  2010cited by this paper
• [Paeoniflorin increases beta-defensin expression and attenuates lesion in the colonic mucosa from mice with oxazolone-induced colitis].

  2010cited by this paper
• Paeoniflorin inhibits systemic inflammation and improves survival in experimental sepsis.

  2009cited by this paper
• The role of epithelial beta-defensins and cathelicidins in host defense of the lung.

  2007cited by this paper
• Defensin participation in innate and adaptive immunity.

  2007cited by this paper
• THE ROLE OF EPITHELIAL β-DEFENSINS AND CATHELICIDINS IN HOST DEFENSE OF THE LUNG

  2007cited by this paper
• Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines.

  2007cited by this paper
• Recent advances in the research and development of human defensins.

  2006cited by this paper
• Paeoniflorin, a novel heat shock protein–inducing compound

  2004cited by this paper
• IL-17 Markedly Up-Regulates β-Defensin-2 Expression in Human Airway Epithelium via JAK and NF-κB Signaling Pathways1

  2004cited by this paper
• Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB.

  2004cited by this paper
• Up-regulation of human β-defensin 2 by interleukin-1β in A549 cells: Involvement of PI3K, PKC, p38 MAPK, JNK, and NF-κB

  2004cited by this paper
• IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.

  2004cited by this paper
• Toll-Like Receptor 4-Dependent Activation of Dendritic Cells by β-Defensin 2

  2002cited by this paper
• Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

  2002cited by this paper
• Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway.

  2002cited by this paper

• The Role of Innate Immunity in Healthy Aging Through Antimicrobial Peptides

  2025cites this paper
• Oleanolic acid improved intestinal immune function by activating and potentiating bile acids receptor signaling in E. coli-challenged piglets

  2024cites this paper
• Preventing Respiratory Viral Diseases with Antimicrobial Peptide Master Regulators in the Lung Airway Habitat

  2023cites this paper
• Mechanisms and regulation of defensins in host defense

  2023cites this paper
• Induction of Endogenous Antimicrobial Peptides to Prevent or Treat Oral Infection and Inflammation

  2023cites this paper
• Current knowledge of leptin in wound healing: A collaborative review

  2022cites this paper
• Effect of paeoniflorin on acute lung injury induced by influenza A virus in mice. Evidences of its mechanism of action.

  2021cites this paper
• Phytopharmaceuticals mediated Furin and TMPRSS2 receptor blocking: can it be a potential therapeutic option for Covid-19?

  2020cites this paper
• EGCG induces β-defensin 3 against influenza A virus H1N1 by the MAPK signaling pathway

  2020cites this paper
• Toll-like receptor 2-mediated induction of avian β-defensin 9 by Lactobacillus rhamnosus and its cellular components in chicken intestinal epithelial cells

  2019influential citation
• Inducible expression of defensins and cathelicidins by nutrients and associated regulatory mechanisms.

  2019cites this paper
• Differential Expression of Antimicrobial Peptides in Streptococcus pneumoniae Keratitis and STAT3-Dependent Expression of LL-37 by Streptococcus pneumoniae in Human Corneal Epithelial Cells

  2019cites this paper
• Saccharomyces cerevisiae β-glucan-induced SBD-1 expression in ovine ruminal epithelial cells is mediated through the TLR-2-MyD88-NF-κB/MAPK pathway

  2019cites this paper
• Saccharomyces cerevisiae mannan induces sheep beta-defensin-1 expression via Dectin-2-Syk-p38 pathways in ovine ruminal epithelial cells

  2019cites this paper
• Astragalus polysaccharides exerts anti‐infective activity by inducing human cathelicidin antimicrobial peptide LL‐37 in respiratory epithelial cells

  2018cites this paper
• Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibition by the Chinese Herbal Remedy Free and Easy Wanderer

  2017cites this paper
• Paeoniflorin inhibits proliferation of endometrial cancer cells via activating MAPK and NF-κB signaling pathways

  2017cites this paper
• Reduction of Ischemic Brain Edema by Combined use of Paeoniflorin and Astragaloside IV via Down‐Regulating Connexin 43

  2017cites this paper
• hBD-2 and hBD-3 are induced in S. pneumoniae infected human macrophages via distinct signaling pathways but exhibit similar immune modulatory functions

  2016cites this paper
• Green tea polyphenol epigallocatechin-3-gallate improves epithelial barrier function by inducing the production of antimicrobial peptide pBD-1 and pBD-2 in monolayers of porcine intestinal epithelial IPEC-J2 cells.

  2016cites this paper
• CHARACTERIZATION OF ANTI-INFLAMMATORY, ANTI-STREPTOCOCCUS PYOGENES AND ANTI-BIOFILM ACTIVITIES OF SUMMER SAVORY PHYTOCHEMICALS

  2015cites this paper
• Paeoniflorin ameliorates ANIT‐induced cholestasis by activating Nrf2 through an PI3K/Akt‐dependent pathway in rats

  2015cites this paper
• Elution-extrusion counter-current chromatography for the separation of two pairs of isomeric monoterpenes from Paeoniae Alba Radix.

  2015cites this paper
• Porcine β-Defensin 2 Attenuates Inflammation and Mucosal Lesions in Dextran Sodium Sulfate–Induced Colitis

  2015cites this paper
• Dehydroandrographolide enhances innate immunity of intestinal tract through up-regulation the expression of hBD-2

  2015cites this paper
• Human Antimicrobial Peptides and Proteins

  2014cites this paper