Modulating effect of Gmelina arborea Linn. on immunosuppressed albino rats

Aim: In the present study, the immunomodulatory effects of roots of Gmelina arborea Linn. were investigated Materials and Methods: Methanolic extract of G. arborea Linn. (MEGA) and its ethyl acetate fraction (EAFME) were used for evaluating the pharmacological activity. The modulating effect was evaluated on humoral and cell-mediated immune response using animal models like cyclophosphamide-induced myelosuppression, delayed-type hypersensitivity (DTH) response, and humoral antibody (HA) titre Results: Both test extracts produced significant increase in HA titre, DTH response, and levels of total white blood cell count Conclusion: This drug is found to be a potential immunostimulant

• Publication year

  2010

• Venue

  Pharmacognosy Research

• Publication date

  2010-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4103/0974-8490.75455PMID 21713139PMCID 3111695
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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