Yeast-based systems for tropical disease drug discovery

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Expert Opinion on Drug Discovery

• Publication date

  2016-03-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1517/17460441.2016.1160052PMID 26931823
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Phylogenetic and Phenotypic Analysis of Salmonella enterica Serovar Weltevreden, an Emerging Agent of Diarrheal Disease in Tropical Regions

  2016cited by this paper
• Yeast-Based High-Throughput Screens to Identify Novel Compounds Active against Brugia malayi

  2016cited by this paper
• Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking

  2015cited by this paper
• Is Caenorhabditis elegans the Magic Bullet for Anthelminthic Drug Discovery?

  2015cited by this paper
• Infrared Fluorescent Imaging as a Potent Tool for In Vitro, Ex Vivo and In Vivo Models of Visceral Leishmaniasis

  2015cited by this paper
• Trypanosomatids see the light: recent advances in bioimaging research.

  2015cited by this paper
• Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?

  2014cited by this paper
• Target identification and mechanism of action in chemical biology and drug discovery.

  2013cited by this paper
• Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

  2013cited by this paper
• Enrichment of Leishmania donovani ATP-binding proteins using a staurosporine capture compound.

  2013cited by this paper
• The utility of yeast as a tool for cell-based, target-directed high-throughput screening

  2013cited by this paper
• An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages

  2012cited by this paper
• Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it?

  2012cited by this paper
• Yeast ATP-binding cassette transporters conferring multidrug resistance.

  2012cited by this paper
• Functional Expression of Parasite Drug Targets and Their Human Orthologs in Yeast

  2011cited by this paper
• Proteomic Analysis of Excretory-Secretory Products of Heligmosomoides polygyrus Assessed with Next-Generation Sequencing Transcriptomic Information

  2011cited by this paper
• Identification of Small Molecule Lead Compounds for Visceral Leishmaniasis Using a Novel Ex Vivo Splenic Explant Model System

  2011cited by this paper
• Recent advances and method development for drug target identification.

  2010cited by this paper
• Establishment of a human hepatocyte line that supports in vitro development of the exo-erythrocytic stages of the malaria parasites Plasmodium falciparum and P. vivax.

  2006cited by this paper
• Yeast as a screening tool.

  2005cited by this paper
• Genetic and genomic approaches to identify and study the targets of bioactive small molecules.

  2004cited by this paper
• Genomic profiling of drug sensitivities via induced haploinsufficiency

  1999cited by this paper
• Haemonchus contortus: cloning and functional expression of a cDNA encoding ornithine decarboxylase and development of a screen for inhibitors.

  1997cited by this paper
• Structural Biology and Crystallization Communications Structural Genomics of Infectious Disease Drug Targets: the Ssgcid

  year unknowncited by this paper

• A yeast-based high-throughput screen identifies inhibitors of trypanosomatid HRG heme transporters with potent leishmanicidal and trypanocidal activity.

  2024cites this paper
• Yeast-based high-throughput screens for discovery of kinase inhibitors for neglected diseases.

  2021cites this paper
• Caracterización de una nueva diana farmacológica en Leishmania spp. e identificación de compuestos activos frente a Trypanosoma brucei

  2018cites this paper
• Heterologous Expression of a Novel Drug Transporter from the Malaria Parasite Alters Resistance to Quinoline Antimalarials

  2018cites this paper
• Tindall, Sarah M. and Vallières, Cindy and Lakhani, Dev H. and Islahudin, Farida and Ting, Kang-Nee and Avery, Simon V. (2018) Heterologous expression of a novel drug transporter from the malaria parasite alters resistance

  2018cites this paper