Insulin receptor substrates-5 and -6 are poor substrates for the insulin receptor.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Molecular Medicine Reports

• Publication date

  2009-11-20

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/mmr_00000239PMID 21472221
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Constitutive plasma membrane targeting and microdomain localization of Dok5 studied by single-molecule microscopy.

  2008cited by this paper
• Identification of Dok-4b, a Dok-4 splice variant with enhanced inhibitory properties.

  2007cited by this paper
• Monitoring the Activation State of Insulin/Insulin-Like Growth Factor-1 Hybrid Receptors Using Bioluminescence Resonance Energy Transfer

  2006cited by this paper
• Dok5 is substrate of TrkB and TrkC receptors and involved in neurotrophin induced MAPK activation.

  2006cited by this paper
• Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase

  2006cited by this paper
• Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase

  2006cited by this paper
• Critical nodes in signalling pathways: insights into insulin action

  2006cited by this paper
• The Muscle Protein Dok-7 Is Essential for Neuromuscular Synaptogenesis

  2006cited by this paper
• Dok-R Mediates Attenuation of Epidermal Growth Factor-Dependent Mitogen-Activated Protein Kinase and Akt Activation through Processive Recruitment of c-Src and Csk

  2005cited by this paper
• Mitochondrial Dok-4 Recruits Src Kinase and Regulates NF-κB Activation in Endothelial Cells*

  2005cited by this paper
• Pleckstrin Homology and Phosphotyrosine-binding Domain-dependent Membrane Association and Tyrosine Phosphorylation of Dok-4, an Inhibitory Adapter Molecule Expressed in Epithelial Cells*

  2004cited by this paper
• Dok-6, a Novel p62 Dok Family Member, Promotes Ret-mediated Neurite Outgrowth*

  2004cited by this paper
• Dynamics of the interaction between the insulin receptor and protein tyrosine‐phosphatase 1B in living cells

  2003cited by this paper
• Two New Substrates in Insulin Signaling, IRS5/DOK4 and IRS6/DOK5*

  2003cited by this paper
• DOK4 and DOK5: new dok-related genes expressed in human T cells

  2003cited by this paper
• Monitoring the activation state of the insulin receptor using bioluminescence resonance energy transfer.

  2001cited by this paper
• Signaling via Shc family adapter proteins

  2001cited by this paper
• Insulin Receptor Substrate-1 Pleckstrin Homology and Phosphotyrosine-binding Domains Are Both Involved in Plasma Membrane Targeting*

  2001cited by this paper
• Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation

  2001cited by this paper
• P62dok, a Negative Regulator of Ras and Mitogen-Activated Protein Kinase (Mapk) Activity, Opposes Leukemogenesis by P210bcr-abl

  2001cited by this paper
• Insulin receptor substrate (IRS) transduction system: distinct and overlapping signaling potential

  2000cited by this paper
• Dok-3, a Novel Adapter Molecule Involved in the Negative Regulation of Immunoreceptor Signaling

  2000cited by this paper
• The functional significance of Shc in insulin signaling as a substrate of the insulin receptor.

  2000cited by this paper
• Intracellular Localization of Phosphatidylinositide 3-kinase and Insulin Receptor Substrate-1 in Adipocytes: Potential Involvement of a Membrane Skeleton

  1998cited by this paper
• Sch proteins are localized on endoplasmic reticulum membranes and are redistributed after tyrosine kinase receptor activation

  1996cited by this paper
• Isoproterenol inhibits insulin-stimulated tyrosine phosphorylation of the insulin receptor without increasing its serine/threonine phosphorylation.

  1995cited by this paper
• Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

  1985cited by this paper

• Insulin Receptor Isoforms and Insulin Growth Factor-like Receptors: Implications in Cell Signaling, Carcinogenesis, and Chemoresistance

  2023cites this paper
• Differential expression of glucose metabolism-related genes and AMP-activated protein kinases in crop tissue of male and female pigeons (Columba livia domestica) during the incubation and chick-rearing periods.

  2022cites this paper
• Insulin receptor substrate 4 deficiency mediates the insulin effect on the epithelial magnesium channel TRPM6 and causes hypomagnesemia

  2022cites this paper
• The Insulin Receptor: An Important Target for the Development of Novel Medicines and Pesticides

  2022cites this paper
• Brief report of the effects of the aerobic, resistance, and high-intensity interval training in type 2 diabetes mellitus individuals

  2018cites this paper
• A bioluminescence resonance energy transfer 2 (BRET2) assay for monitoring seven transmembrane receptor and insulin receptor crosstalk

  2017cites this paper
• Brief report of the effects of the aerobic, resistance, and high-intensity interval training in type 2 diabetes mellitus individuals

  2017cites this paper
• Insulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycle

  2016cites this paper
• Differential Effects of Camel Milk on Insulin Receptor Signaling – Toward Understanding the Insulin-Like Properties of Camel Milk

  2016cites this paper
• Tissue specific functions of insulin receptor substrate family members based on their molecular structures

  2016cites this paper
• FOR DOCTORAL DEGREE ( Ph . D . )

  2015cites this paper
• Insulin receptor signaling in normal and insulin-resistant states.

  2014cites this paper
• Positive Regulation of Insulin Signaling by Neuraminidase 1

  2013cites this paper
• BRET Biosensor Analysis of Receptor Tyrosine Kinase Functionality

  2013influential citation
• Sam68 interacts with IRS1.

  2012cites this paper
• From signal transduction to signal interpretation: An alternative model for the molecular function of insulin receptor substrates

  2012cites this paper
• A BRET assay for monitoring insulin receptor interactions and ligand pharmacology

  2012cites this paper
• Molecular Basis of Signaling Specificity of Insulin and IGF Receptors: Neglected Corners and Recent Advances

  2011cites this paper
• Docking proteins

  2010cites this paper