Plasma methylated septin 9: a colorectal cancer screening marker

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Expert Review of Molecular Diagnostics

• Publication date

  2015-01-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1586/14737159.2015.975212PMID 25429690
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Septin 9 promoter region methylation in free circulating DNA—potential role in noninvasive diagnosis of lung cancer: preliminary report

  2014cited by this paper
• Lower endoscopy reduces colorectal cancer incidence in older individuals.

  2014cited by this paper
• Investigation of cell free BIRC5 mRNA as a serum diagnostic and prognostic biomarker for colorectal cancer

  2014cited by this paper
• Blood-Based Testing for Colorectal Cancer Screening

  2014influential reference
• Preferences for blood-based colon cancer screening differ by race/ethnicity.

  2014cited by this paper
• Plasma Septin9 versus Fecal Immunochemical Testing for Colorectal Cancer Screening: A Prospective Multicenter Study

  2014cited by this paper
• Postoperative serum methylation levels of TAC1 and SEPT9 are independent predictors of recurrence and survival of patients with colorectal cancer

  2014cited by this paper
• Validation of a real-time PCR-based qualitative assay for the detection of methylated SEPT9 DNA in human plasma.

  2014influential reference
• Microsatellite instability testing in colorectal carcinoma: a practical guide.

  2014cited by this paper
• Mitotic Regulation of SEPT9 Protein by Cyclin-dependent Kinase 1 (Cdk1) and Pin1 Protein Is Important for the Completion of Cytokinesis*

  2013cited by this paper
• DNA methylation in cancer: a gene silencing mechanism and the clinical potential of its biomarkers.

  2013cited by this paper
• Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer.

  2013cited by this paper
• KRAS and BRAF mutation status in circulating colorectal tumor cells and their correlation with primary and metastatic tumor tissue

  2013cited by this paper
• Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island

  2013cited by this paper
• Prospective evaluation of methylated SEPT9 in plasma for detection of asymptomatic colorectal cancer

  2013influential reference
• SEPT9_i1 is required for the association between HIF-1α and importin-α to promote efficient nuclear translocation

  2013cited by this paper
• Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012.

  2013cited by this paper
• Serrated pathway: alternative route to colorectal cancer.

  2013cited by this paper
• Age-associated epigenetic drift: implications, and a case of epigenetic thrift?

  2013cited by this paper
• Diagnostic and Prognostic Value of SHOX2 and SEPT9 DNA Methylation and Cytology in Benign, Paramalignant and Malignant Pleural Effusions

  2013cited by this paper
• Plasma MiR-21: A Potential Diagnostic Marker of Colorectal Cancer

  2012cited by this paper
• The sensitivity and specificity of guaiac and immunochemical fecal occult blood tests for the detection of advanced colonic adenomas and cancer

  2012cited by this paper
• Functions of DNA methylation: islands, start sites, gene bodies and beyond

  2012cited by this paper
• Comprehensive molecular characterization of human colon and rectal cancer

  2012cited by this paper
• Detection of Methylated SEPT9 in Plasma Is a Reliable Screening Method for Both Left- and Right-Sided Colon Cancers

  2012cited by this paper
• Review of biomarkers in colorectal cancer

  2012cited by this paper
• Next-generation stool DNA test accurately detects colorectal cancer and large adenomas.

  2012cited by this paper
• European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition – Organisation

  2012cited by this paper
• Discovery and Validation of Molecular Biomarkers for Colorectal Adenomas and Cancer with Application to Blood Testing

  2012cited by this paper
• A multiplex serum protein assay for determining the probability of colorectal cancer.

  2012cited by this paper
• Septin 9 methylated DNA is a sensitive and specific blood test for colorectal cancer

  2011influential reference
• Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression

  2011cited by this paper
• Meta-analysis of new genome-wide association studies of colorectal cancer risk

  2011cited by this paper
• Microtubules support a disk-like septin arrangement at the plasma membrane of mammalian cells

  2011cited by this paper
• Organized colorectal cancer screening in integrated health care systems.

  2011cited by this paper
• A role for septins in the interaction between the Listeria monocytogenes INVASION PROTEIN InlB and the Met receptor.

  2011cited by this paper
• Performance of Epigenetic Markers SEPT9 and ALX4 in Plasma for Detection of Colorectal Precancerous Lesions

  2010influential reference
• Targeted Knockdown of SEPT9_v1 Inhibits Tumor Growth and Angiogenesis of Human Prostate Cancer Cells Concomitant with Disruption of Hypoxia-Inducible Factor-1 Pathway

  2010cited by this paper
• Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial.

  2010cited by this paper
• From discovery to the clinic: the novel DNA methylation biomarker (m)SEPT9 for the detection of colorectal cancer in blood.

  2010cited by this paper
• Potential of a New Blood Test for Colorectal Cancer Screening - The Septin 9 Gene Biomarker

  2010cited by this paper
• Molecular origins of cancer: Molecular basis of colorectal cancer.

  2009cited by this paper
• Circulating methylated SEPT9 DNA in plasma is a biomarker for colorectal cancer.

  2009influential reference
• A blood‐based biomarker panel for stratifying current risk for colorectal cancer

  2009cited by this paper
• Septins Regulate Bacterial Entry into Host Cells

  2009cited by this paper
• AML1 amplification and 17q25 deletion in a case of childhood acute lymphoblastic leukemia

  2009cited by this paper
• DNA Integrity in Plasma and Serum of Patients with Malignant and Benign Diseases

  2008cited by this paper
• Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps.

  2008cited by this paper
• DNA methylation biomarkers for blood-based colorectal cancer screening.

  2008cited by this paper
• Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline from the American Cancer Society, the US Multi‐Society Task Force on Colorectal Cancer, and the American College of Radiology * †

  2008cited by this paper
• Sensitive Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay

  2008cited by this paper
• Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma.

  2008cited by this paper
• Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology.

  2008cited by this paper
• Systematic review of the effectiveness of population screening for colorectal cancer.

  2007cited by this paper
• An MLL-SEPT9 fusion and t(11;17)(q23;q25) associated with de novo myelodysplastic syndrome.

  2007cited by this paper
• Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease

  2007cited by this paper
• Comparative DNA methylation analysis in normal and tumour tissues and in cancer cell lines using differential methylation hybridisation.

  2007cited by this paper
• Plasma levels of tumor M2-pyruvate kinase should not be used as a tumor marker for hematological malignancies and solid tumors

  2006cited by this paper
• Altered patterns of transcription of the septin gene, SEPT9, in ovarian tumorigenesis

  2006cited by this paper
• CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

  2006cited by this paper
• Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours

  2005cited by this paper
• Analysis of mammalian septin expression in human malignant brain tumors.

  2004cited by this paper
• Tumor type M2 pyruvate kinase expression in gastric cancer, colorectal cancer and controls.

  2004cited by this paper
• The pathobiology of the septin gene family

  2004cited by this paper
• The Septin 9 (MSF) gene is amplified and overexpressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines.

  2003cited by this paper
• The colorectal adenoma–carcinoma sequence

  2002cited by this paper
• Tumour class prediction and discovery by microarray-based DNA methylation analysis.

  2001cited by this paper
• Genomic organization, complex splicing pattern and expression of a human septin gene on chromosome 17q25.3

  2001cited by this paper
• Septins: cytoskeletal polymers or signalling GTPases?

  1999cited by this paper
• CpG island methylator phenotype in colorectal cancer.

  1999cited by this paper
• Colorectal adenoma-carcinoma sequence.

  1996cited by this paper
• A genetic model for colorectal tumorigenesis.

  1990influential reference

• Current status and progress of diagnosis and treatment of postoperative recurrence of gastrointestinal peritoneal metastases

  2025cites this paper
• Cracking the Code of Colorectal Cancer Screening: An Overview With a Focus on Current and Emerging Screening Methods

  2025cites this paper
• The NRF2-KEAP1 pathway and epigenetic control in colorectal cancer: A promising prognostic and predictive biomarker

  2024cites this paper
• The Clinical Significance of Septin 9 and Colon Cancer Specific Antigen-2 (CCSA-2) in Colorectal Cancer

  2023cites this paper
• Circulating tumor DNA for monitoring colorectal cancer: A prospective observational study to assess the presence of methylated SEPT9 and VIM promoter genes and its role as a biomarker in colorectal cancer management.

  2023cites this paper
• Current and future colorectal cancer screening strategies

  2022cites this paper
• Liquid Biopsy and Artificial Intelligence as Tools to Detect Signatures of Colorectal Malignancies: A Modern Approach in Patient’s Stratification

  2022cites this paper
• Molecular testing panel in colorectal cancer

  2022cites this paper
• Detection of free DNA septin 9 gene methylation in plasma.

  2021cites this paper
• Dual-modality loop-mediated isothermal amplification for pretreatment-free detection of Septin9 methylated DNA in colorectal cancer

  2021cites this paper
• When Tissue is an Issue the Liquid Biopsy is Nonissue: A Review

  2021cites this paper
• Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB).

  2020cites this paper
• Investigation of GHSR methylation levels in thymomas from patients with Myasthenia Gravis.

  2020cites this paper
• Colon Cancer Biomarkers: Implications for Personalized Medicine

  2020cites this paper
• Circulating Tumour DNAs and Non-Coding RNAs as Liquid Biopsies for the Management of Colorectal Cancer Patients

  2020cites this paper
• ITIH5 and ECRG4 DNA Methylation Biomarker Test (EI-BLA) for Urine-Based Non-Invasive Detection of Bladder Cancer

  2020cites this paper
• Utility of the methylated SEPT9 test for the early detection of colorectal cancer: a systematic review and meta-analysis of diagnostic test accuracy

  2020cites this paper
• DNA Methylation-Based Testing in Liquid Biopsies as Detection and Prognostic Biomarkers for the Four Major Cancer Types

  2020cites this paper
• [Characteristics and diagnostic applications of circulating cell-free DNA in colorectal cancer].

  2019cites this paper
• A Novel Prognostic DNA Methylation Panel for Colorectal Cancer

  2019cites this paper
• Biopsia liquida: una review

  2019cites this paper
• A pilot study of new promising non-coding RNA diagnostic biomarkers for early-stage colorectal cancers

  2019cites this paper
• Detection, prediction, and prognosis: blood circulating microRNA as novel molecular markers of head and neck cancer patients

  2019cites this paper
• Enhanced-ice-COLD-PCR for the Sensitive Detection of Rare DNA Methylation Patterns in Liquid Biopsies.

  2019cites this paper
• Colorectal Cancer Screening and Surveillance

  2019cites this paper
• Colorectal Cancer Screening.

  2019cites this paper
• Circulating cell-free nucleic acids as biomarkers in colorectal cancer screening and diagnosis - an update

  2019cites this paper
• NKX6.1 hypermethylation predicts the outcome of stage II colorectal cancer patients undergoing chemotherapy

  2018cites this paper
• Cell-Free Circulating Methylated SEPT9 for Noninvasive Diagnosis and Monitoring of Colorectal Cancer

  2018cites this paper
• Epigenetic Modifications as Biomarkers of Tumor Development, Therapy Response, and Recurrence across the Cancer Care Continuum

  2018cites this paper
• [In vivo analysis of circulating cell-free DNA release and degradation].

  2018cites this paper
• Blood-based DNA Methylation Biomarkers for Early Detection of Colorectal Cancer

  2018cites this paper
• Diagnostic Assessment of septin9 DNA Methylation for Colorectal Cancer Using Blood Detection: A Meta-Analysis

  2018cites this paper
• Epigenetica e cancro del colon-retto: limiti e prospettive

  2018cites this paper
• Klinische Bedeutung der Epigenetik

  2018cites this paper
• Genomic approach to translational studies in colorectal cancer

  2018cites this paper
• Epigenetic Signatures in the Diagnosis and Prognosis of Cancer

  2018cites this paper
• A sejten kívüli szabad DNS felszabadulásának és degradációjának in vivo elemzése

  2018cites this paper
• Enrichment of methylated molecules using enhanced-ice-co-amplification at lower denaturation temperature-PCR (E-ice-COLD-PCR) for the sensitive detection of disease-related hypermethylation.

  2018cites this paper
• Advance in plasma SEPT9 gene methylation assay for colorectal cancer early detection

  2018cites this paper
• COLORECTAL CANCER: A SMALL REVIEW OF CURRENT AND FUTURE MOLECULAR SCREENING MARKERS AND THE FIRST STEPS TO PERSONALIZED MEDICINE

  2017cites this paper
• Oncogenic role of PDK4 in human colon cancer cells

  2017cites this paper
• Acute myocardial infarction or stroke in occult colorectal cancer: Epiphenomena of the degree of epigenetic deregulation of SEPT9 gene?

  2017cites this paper
• Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples

  2017cites this paper
• Genomic approaches to accelerate cancer interception.

  2017cites this paper
• Platelets, circulating tumor cells, and the circulome

  2017cites this paper
• A pooled analysis of the diagnostic efficacy of plasmic methylated septin-9 as a novel biomarker for colorectal cancer.

  2017cites this paper
• A vastagbéldaganat kialakulásának in situ és perifériás vér biomarkerei

  2016cites this paper
• Nouvelles méthodes de détection de l'ADN tumoral circulant par PCR digitale en gouttelettes : application au suivi des patients

  2016cites this paper
• OSMR and SEPT9: promising biomarkers for detection of colorectal cancer based on blood-based tests

  2016cites this paper
• Epigenetic modifications: mechanisms of disease and biomarkers of food allergy.

  2016cites this paper
• Circulating cell-free nucleic acids as biomarkers in colorectal cancer screening and diagnosis

  2016cites this paper
• In situ and peripheral biomarkers of development of colorectal cancer

  2015cites this paper
• Familial colorectal cancer screening: When and what to do?

  2015cites this paper
• Cancer prevention: state of the art and future prospects

  2015influential citation
• World Journal of Gastrointestinal Oncology

  year unknowncites this paper