It was shown previously that endotubin, an integral membrane protein of endosomes, regulates the trafficking of tight junction proteins between endosomes and the tight junctions. Here it is shown that endotubin regulates YAP localization on endosomes through its interaction with AMOT and thus may play a role in contact inhibition.
Endosomal regulation of contact inhibition through the AMOT:YAP pathway
Christopher M. Cox,Edward K. Mandell,L. Stewart,Ruifeng Lu,Debra L. Johnson,S. D. Mccarter,Andre L. P. Tavares,Raymond B. Runyan,Sourav Ghosh,Jean M. Wilson
Published 2015 in Molecular Biology of the Cell
ABSTRACT
PUBLICATION RECORD
- Publication year
2015
- Venue
Molecular Biology of the Cell
- Publication date
2015-07-15
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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