The sphingosine-1-phosphate receptor agonist FTY720 prevents the development of anti-glomerular basement membrane glomerulonephritis

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Molecular Biology Reports

• Publication date

  2011-08-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s11033-011-0750-1PMID 21833515
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• FTY720 and everolimus in de novo renal transplant patients at risk for delayed graft function: results of an exploratory one‐yr multicenter study

  2009cited by this paper
• Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist.

  2008cited by this paper
• New immunosuppresor strategies in the treatment of murine lupus nephritis

  2007cited by this paper
• S1P modulator FTY720 limits matrix expansion in acute anti-thy1 mesangioproliferative glomerulonephritis.

  2007cited by this paper
• FTY720 attenuates accumulation of EMAP-II+ and MHC-II+ monocytes in early lesions of rat traumatic brain injury

  2007cited by this paper
• Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology.

  2007cited by this paper
• Endogenous myeloperoxidase promotes neutrophil-mediated renal injury, but attenuates T cell immunity inducing crescentic glomerulonephritis.

  2007cited by this paper
• Oral fingolimod (FTY720) for relapsing multiple sclerosis.

  2006cited by this paper
• Sphingosine 1‐phosphate receptor modulators: a new class of immunosuppressants

  2006cited by this paper
• FTY720/Cyclosporine Regimens in De Novo Renal Transplantation: A 1‐Year Dose‐Finding Study

  2006cited by this paper
• Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

  2005cited by this paper
• FTY720, A Novel Immunomodulator: Efficacy and Safety Results from the First Phase 2A Study in de novo Renal Transplantation

  2005cited by this paper
• FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors.

  2005cited by this paper
• Recombinant uteroglobin prevents the experimental crescentic glomerulonephritis.

  2004cited by this paper
• Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

  2004cited by this paper
• FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation.

  2004cited by this paper
• Calcium citrate ameliorates the progression of chronic renal injury.

  2004cited by this paper
• FTY720: Sphingosine 1‐Phosphate Receptor‐1 in the Control of Lymphocyte Egress and Endothelial Barrier Function

  2004cited by this paper
• Structural and functional characteristics of S1P receptors

  2004cited by this paper
• Intracellular signal transduction pathways activated by ceramide and its metabolites.

  2003cited by this paper
• Egress: a receptor‐regulated step in lymphocyte trafficking

  2003cited by this paper
• The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors*

  2002influential reference
• FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity.

  2002cited by this paper
• Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

  2002cited by this paper
• Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus.

  2002cited by this paper
• FTY720 Immunosuppression Impairs Effector T Cell Peripheral Homing Without Affecting Induction, Expansion, and Memory1

  2000cited by this paper
• Involvement of Sphingosine in Mitochondria-dependent Fas-induced Apoptosis of Type II Jurkat T Cells*

  2000cited by this paper
• Regulatory interactions of alphabeta and gammadelta T cells in glomerulonephritis.

  2000cited by this paper
• Abolition of anti‐glomerular basement membrane antibody‐mediated glomerulonephritis in FcRγ‐deficient mice

  2000cited by this paper
• IFN-γ Mediates Crescent Formation and Cell-Mediated Immune Injury in Murine Glomerulonephritis

  1999cited by this paper
• IFN-gamma mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis.

  1999cited by this paper
• Interleukin-4 deficiency enhances Th1 responses and crescentic glomerulonephritis in mice.

  1998cited by this paper
• Th2 responses induce humorally mediated injury in experimental anti-glomerular basement membrane glomerulonephritis.

  1997cited by this paper
• Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice.

  1997cited by this paper
• Antibody independent crescentic glomerulonephritis in mu chain deficient mice.

  1997cited by this paper
• The in vivo induction of lymphocyte apoptosis in MRL‐lpr/lpr mice treated with FTY720

  1997cited by this paper
• Mechanisms of T cell‐induced glomerular injury in anti‐glomeruler basement membrane (GBM) glomerulonephritis in rats

  1997cited by this paper
• Evidence for delayed-type hypersensitivity mechanisms in glomerular crescent formation.

  1994cited by this paper

• A Rheostat of Ceramide and Sphingosine-1-Phosphate as a Determinant of Oxidative Stress-Mediated Kidney Injury

  2022cites this paper
• Regulatory role of SphK1 in TLR7/9‐dependent type I interferon response and autoimmunity

  2020cites this paper
• Sphingosine-1-phosphate in anti-neutrophil cytoplasmic antibody-associated vasculitis: coagulation-related clinical indicators and complications

  2020cites this paper
• Multiple Sclerosis Drug Fingolimod Induces Thrombotic Microangiopathy in Deoxycorticosterone Acetate/Salt Hypertension

  2018cites this paper
• Sphingolipid signaling in renal fibrosis.

  2018cites this paper
• Sphingolipids in Genetic and Acquired Forms of Chronic Kidney Diseases.

  2017cites this paper
• FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway

  2014cites this paper
• Treatment with the immunomodulator FTY720 (fingolimod) significantly reduces renal inflammation in murine unilateral ureteral obstruction.

  2014cites this paper
• Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases.

  2014cites this paper
• FTY720 attenuates tubulointerstitial inflammation and fibrosis in subtotally nephrectomized rats

  2013cites this paper
• Sphingosine 1-Phosphate in Renal Diseases

  2013cites this paper
• Increased Serum Concentration of Sphingosine-1-phosphate in Juvenile-onset Systemic Lupus Erythematosus

  2012cites this paper
• FTY720 induces cell cycle arrest and apoptosis of rat glomerular mesangial cells

  2012cites this paper