New cationic polyprenyl derivative proposed as a lipofecting agent.

Z. Madeja,M. Rak,Ewa Wybieralska,I. Rózański,M. Masnyk,M. Chmielewski,R. Lysek,T. Chojnacki,W. Jankowski,Ewa Ciepichal,E. Swiezewska,M. Tekle,G. Dallner

Published 2007 in Acta Biochimica Polonica

ABSTRACT

Cationic linear poly-cis-isoprenoid prepared from natural plant polyprenol in a mixture with dioleyl phosphatidylethanolamine was found to be an effective lipofection agent for eukaryotic cells. The transfecting activity is related to the poly-cis structure of the polyprenyl chain.

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