Abdominal aortic aneurysms: an autoimmune disease?

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Trends in Molecular Medicine

• Publication date

  2008-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.molmed.2008.09.008PMID 18980864
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vessel Wall–Embedded Dendritic Cells Induce T-Cell Autoreactivity and Initiate Vascular Inflammation

  2008cited by this paper
• Epigenetics, aging, and autoimmunity

  2008cited by this paper
• Medical management of small abdominal aortic aneurysms.

  2008cited by this paper
• Aortic Aneurysms: An Immune Disease With a Strong Genetic Component

  2008cited by this paper
• Characterisation of fractalkine/CX3CL1 and fractalkine receptor (CX3CR1) expression in abdominal aortic aneurysm disease.

  2008cited by this paper
• Differences in synovial tissue infiltrates between anti-cyclic citrullinated peptide-positive rheumatoid arthritis and anti-cyclic citrullinated peptide-negative rheumatoid arthritis.

  2008cited by this paper
• Adventitial Mast Cells Contribute to Pathogenesis in the Progression of Abdominal Aortic Aneurysm

  2008cited by this paper
• Mutations in the Positional Candidate Genes in Patients With Syndromic and Nonsyndromic Forms of TAAD

  2008cited by this paper
• Effect of statins on proteolytic activity in the wall of abdominal aortic aneurysms

  2008cited by this paper
• The role of T lymphocytes in rheumatoid arthritis and other autoimmune diseases.

  2008cited by this paper
• The Efficacy of Pharmacotherapy for Decreasing the Expansion Rate of Abdominal Aortic Aneurysms: A Systematic Review and Meta-Analysis

  2008cited by this paper
• Current issues in the treatment of women with abdominal aortic aneurysm.

  2008cited by this paper
• Molecular mechanisms of autoimmunity

  2008cited by this paper
• Regression of Abdominal Aortic Aneurysms by Simultaneous Inhibition of Nuclear Factor &kgr;B and Ets in a Rabbit Model

  2007cited by this paper
• Impaired Fas-induced apoptosis of T lymphocytes in patients with abdominal aortic aneurysms.

  2007cited by this paper
• Negative association between infra-renal aortic diameter and glycaemia: the Health in Men Study.

  2007cited by this paper
• Inflammatory abdominal aortic aneurysm.

  2007cited by this paper
• Current management of infrarenal abdominal aortic aneurysms.

  2007cited by this paper
• Abdominal aortic aneurysm in women: prevalence, risk factors, and implications for screening.

  2007cited by this paper
• Increased natural killer cell activity in patients with an abdominal aortic aneurysm

  2006cited by this paper
• Autoimmune aspects of chronic periaortitis.

  2006cited by this paper
• Abdominal aortic aneurysms: an underestimated type of immune-mediated large vessel arteritis?

  2006cited by this paper
• Abdominal Aortic Aneurysm as a Complex Multifactorial Disease

  2006cited by this paper
• Abdominal Aortic Aneurysm Is a Specific Antigen‐Driven T Cell Disease

  2006cited by this paper
• High Prevalence of Circulating CD4+CD28− T-Cells in Patients With Small Abdominal Aortic Aneurysms

  2005cited by this paper
• Predominance of type 1 CD4+T cells in human abdominal aortic aneurysm

  2005cited by this paper
• Functional characterization of T cells in abdominal aortic aneurysms

  2005cited by this paper
• Genome-wide linkage in three Dutch families maps a locus for abdominal aortic aneurysms to chromosome 19q13.3.

  2005cited by this paper
• Reduced Immunoregulatory CD31+ T Cells in Patients With Atherosclerotic Abdominal Aortic Aneurysm

  2005cited by this paper
• Atherosclerotic Abdominal Aortic Aneurysm and the Interaction Between Autologous Human Plaque-Derived Vascular Smooth Muscle Cells, Type 1 NKT, and Helper T Cells

  2005cited by this paper
• Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase

  2005cited by this paper
• Key Roles of CD4+ T Cells and IFN-γ in the Development of Abdominal Aortic Aneurysms in a Murine Model1

  2004cited by this paper
• T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection.

  2004cited by this paper
• Th2-predominant inflammation and blockade of IFN-gamma signaling induce aneurysms in allografted aortas.

  2004cited by this paper
• Genome Scan for Familial Abdominal Aortic Aneurysm Using Sex and Family History as Covariates Suggests Genetic Heterogeneity and Identifies Linkage to Chromosome 19q13

  2004cited by this paper
• Genetic markers of disease susceptibility and severity in giant cell arteritis and polymyalgia rheumatica.

  2003cited by this paper
• The value of sensitive imaging modalities in rheumatoid arthritis

  2003cited by this paper
• Natural killer cells and autoimmunity

  2003cited by this paper
• Differential Effects of Doxycycline, a Broad-Spectrum Matrix Metalloproteinase Inhibitor, on Angiotensin II–Induced Atherosclerosis and Abdominal Aortic Aneurysms

  2003cited by this paper
• The role of a putative microfibrillar protein (80 kDa) in abdominal aortic aneurysm disease.

  2003cited by this paper
• Genetic analysis on HLA loci in Japanese patients with abdominal aortic aneurysm.

  2003cited by this paper
• Familial abdominal aortic aneurysms: collection of 233 multiplex families.

  2003cited by this paper
• Inflammatory aortic aneurysm is associated with increased incidence of autoimmune disease.

  2003cited by this paper
• Characterisation of T and B lymphocytes infiltrating abdominal aortic aneurysms.

  2003cited by this paper
• The expansion of CD4+CD28- T cells in patients with rheumatoid arthritis

  2003cited by this paper
• Controlling the expansion of abdominal aortic aneurysms

  2003cited by this paper
• TH2 Predominant Immune Responses Prevail in Human Abdominal Aortic Aneurysm

  2002cited by this paper
• T(H)2 predominant immune responses prevail in human abdominal aortic aneurysm.

  2002cited by this paper
• Human leukocyte antigen class II immune response genes, female gender, and cigarette smoking as risk and modulating factors in abdominal aortic aneurysms.

  2002cited by this paper
• A subset of natural killer cells is greatly expanded within inflamed joints.

  2002cited by this paper
• Long-term outcomes of immediate repair compared with surveillance of small abdominal aortic aneurysms.

  2002cited by this paper
• Epidemiology of abdominal aortic aneurysms in the Asian community

  2001cited by this paper
• Ectopic Lymphoid Organogenesis A Fast Track for Autoimmunity

  2001cited by this paper
• Vascular-associated lymphoid tissue (VALT) involvement in aortic aneurysm.

  2001cited by this paper
• Genetic similarity in inflammatory and degenerative abdominal aortic aneurysms: a study of human leukocyte antigen class II disease risk genes.

  2001cited by this paper
• Sex differences in autoimmune disease

  2001cited by this paper
• Incidence of femoral and popliteal artery aneurysms in patients with abdominal aortic aneurysms.

  2000cited by this paper
• Inhibition of prostaglandin E2 synthesis in abdominal aortic aneurysms: implications for smooth muscle cell viability, inflammatory processes, and the expansion of abdominal aortic aneurysms.

  1999cited by this paper
• Chlamydia pneumoniae reactive T lymphocytes in the walls of abdominal aortic aneurysms

  1999cited by this paper
• Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms.

  1998cited by this paper
• Genetic risk factor for abdominal aortic aneurysm: HLA-DR2(15), a Japanese study.

  1998cited by this paper
• Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms.

  1997cited by this paper
• Perforin-secreting killer cell infiltration in the aortic tissue of patients with atherosclerotic aortic aneurysm.

  1997cited by this paper
• Analysis of the T cell receptor Vβ repertoire in human aortic aneurysms

  1997cited by this paper
• Analysis of the T cell receptor V beta repertoire in human aortic aneurysms.

  1997cited by this paper
• Unrestricted usage of immunoglobulin heavy chain genes in B cells infiltrating the wall of atherosclerotic abdominal aortic aneurysms.

  1997cited by this paper
• Expression of two novel recombinant proteins from aortic adventitia (kappafibs) sharing amino acid sequences with cytomegalovirus.

  1997cited by this paper
• Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms

  1997cited by this paper
• Elevated circulating levels of inflammatory cytokines in patients with abdominal aortic aneurysm.

  1997cited by this paper
• Partial amino acid sequence of a novel 40-kDa human aortic protein, with vitronectin-like, fibrinogen-like, and calcium binding domains: aortic aneurysm-associated protein-40 (AAAP-40) [human MAGP-3, proposed].

  1996cited by this paper
• Activated forms of MMP2 and MMP9 in abdominal aortic aneurysms.

  1996cited by this paper
• Features of autoimmunity in the abdominal aortic aneurysm.

  1996cited by this paper
• Molecular Mimicry in Human Aortic Aneurysmal Diseases a

  1996cited by this paper
• Aneurysms of the abdominal aorta: familial and genetic aspects in three hundred thirteen pedigrees.

  1995cited by this paper
• Racial differences in the incidence of femoral bypass and abdominal aortic aneurysmectomy in Massachusetts: relationship to cardiovascular risk factors.

  1995cited by this paper
• Screening for Abdominal Aortic Aneurysms

  1994cited by this paper
• Are Aortic Aneurysms Caused by Atherosclerosis?

  1992cited by this paper
• Interleukin-1β and tumor necrosis factor-α release in normal and diseased human infrarenal aortas * ** *

  1992cited by this paper
• Interleukin-1 beta and tumor necrosis factor-alpha release in normal and diseased human infrarenal aortas.

  1992cited by this paper
• Suggested standards for reporting on arterial aneurysms. Subcommittee on Reporting Standards for Arterial Aneurysms, Ad Hoc Committee on Reporting Standards, Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery.

  1991cited by this paper
• Suggested standards for reporting on arterial aneurysms

  1991cited by this paper
• The role of inflammation in nonspecific abdominal aortic aneurysm disease

  1991cited by this paper
• On the inheritance of abdominal aortic aneurysm.

  1991cited by this paper
• Human abdominal aortic aneurysms. Immunophenotypic analysis suggesting an immune-mediated response.

  1990cited by this paper
• Multifactorial inheritance of abdominal aortic aneurysm.

  1987cited by this paper
• Plasma cell infiltrates in atherosclerotic abdominal aortic aneurysms.

  1986cited by this paper
• Screening for abdominal aortic aneurysm

  1985cited by this paper
• Fifty families with abdominal aortic aneurysms in two or more first-order relatives.

  1984cited by this paper
• Familial abdominal aortic aneurysms

  1977cited by this paper

• From Single Cells to Targetable Immune Mechanisms in Congenital Heart Disease, Ischemic Heart Disease, and Abdominal Aortic Aneurysm.

  2026cites this paper
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  2025cites this paper
• Extravascular administration of IGF1R antagonists protects against aortic aneurysm in rodent and porcine models

  2024cites this paper
• Integrative analysis of multi-omics and machine learning highlighted an m6A-related mRNA signature as a robust AAA progression predictor

  2023cites this paper
• Role of Mitochondria in the Chronification of Inflammation: Focus on Dysfunctional Mitophagy and Mitochondrial DNA Mutations

  2023cites this paper
• C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms

  2023cites this paper
• 3, 4-Benzopyrene (Bap) aggravated abdominal aortic aneurysm formation by targeting pyroptosis in smooth muscle cells through ET-1 mediated NLRP3-inflammasome activation.

  2023cites this paper
• Genome-Wide Identification of Immune-Related Alternative Splicing and Splicing Regulators Involved in Abdominal Aortic Aneurysm

  2022cites this paper
• The AIM2 Inflammasome: A Novel Biomarker and Target in Cardiovascular Disease.

  2022cites this paper
• The role of phosphoinositide 3-kinases in immune-inflammatory responses: potential therapeutic targets for abdominal aortic aneurysm

  2022cites this paper
• Preservation of Smooth Muscle Cell Integrity and Function: A Target for Limiting Abdominal Aortic Aneurysm Expansion?

  2022cites this paper
• Association of IL-10 and CRP with Pulse Wave Velocity in Patients with Abdominal Aortic Aneurysm

  2022cites this paper
• Inflammasomes in the Pathophysiology of Aortic Disease

  2021cites this paper
• Pathophysiological Aspects of the Development of Abdominal Aortic Aneurysm with a Special Focus on Mitochondrial Dysfunction and Genetic Associations

  2021cites this paper
• Constrained Mixture Models of Soft Tissue Growth and Remodeling – Twenty Years After

  2021cites this paper
• Association of High-Sensitivity C-Reactive Protein With Aneurysm Sac Shrinkage in Patients Undergoing Endovascular Abdominal Aneurysm Repair

  2021cites this paper
• Nivolumab-Induced Periaortitis Demonstrated by FDG PET/CT.

  2020cites this paper
• Overview of IgG4-related aortitis and periaortitis. A decade since their first description.

  2020cites this paper
• Genome-Wide Expression Profiling Unveils Autoimmune Response Signatures in the Perivascular Adipose Tissue of Abdominal Aortic Aneurysm

  2019cites this paper
• High-Throughput Data Reveals Novel Circular RNAs via Competitive Endogenous RNA Networks Associated with Human Intracranial Aneurysms

  2019influential citation
• Inflammasome activity in leucocytes decreases with abdominal aortic aneurysm progression

  2019cites this paper
• Popliteal pseudoaneurysm after FOLFOX chemotherapy for metastatic colorectal cancer

  2019cites this paper
• Epigenetic regulation of regulatory T cells in patients with abdominal aortic aneurysm

  2019cites this paper
• Modulation of Immune-Inflammatory Responses in Abdominal Aortic Aneurysm: Emerging Molecular Targets

  2018cites this paper
• Abnormal acetylation of FOXP3 regulated by SIRT-1 induces Treg functional deficiency in patients with abdominal aortic aneurysms.

  2018cites this paper
• Perivascular scaffolds loaded with adipose tissue-derived stromal cells attenuate development and progression of abdominal aortic aneurysm in rats.

  2018cites this paper
• Rastreio do Aneurisma da Aorta Abdominal, estado atual da arte.

  2018cites this paper
• Characterization of CD 4 + T Cell Subsets in Patients with Abdominal Aortic Aneurysms

  2018cites this paper
• Characterization of CD4+ T Cell Subsets in Patients with Abdominal Aortic Aneurysms

  2018cites this paper
• Autoimmunity in the Abdominal Aortic Aneurysm and its Association with Smoking

  2017cites this paper
• Association of ficolin‐3 with abdominal aortic aneurysm presence and progression

  2017cites this paper
• Characterization of Fc gamma receptor IIb expression within abdominal aortic aneurysm.

  2017cites this paper
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  2017influential citation
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  2017cites this paper
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  2017influential citation
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  2016cites this paper
• Redox proteomic analysis of serum from aortic anerurysm patients: insights on oxidation of specific protein target.

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016influential citation
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  2016influential citation
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2012cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
• Reproducibility of ultrasound measurement of the abdominal aorta

  2011cites this paper
• Immunoglobulin G4-related inflammatory aortic aneurysm

  2011cites this paper
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  2010cites this paper
• Deficient CD4+CD25+ T Regulatory Cell Function in Patients With Abdominal Aortic Aneurysms

  2010cites this paper
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  2010cites this paper
• Diameter of the infrarenal aorta as a risk factor for abdominal aortic aneurysm: the Tromsø Study, 1994-2001.

  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper