A preliminary open-label study of 5-HT1A partial agonist tandospirone for behavioural and psychological symptoms associated with dementia.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  International Journal of Neuropsychopharmacology

• Publication date

  2007-04-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1017/S1461145706007000PMID 16817981
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Risk of death in elderly users of conventional vs. atypical antipsychotic medications.

  2005cited by this paper
• Behavioral and psychological symptoms in dementia: the role of atypical antipsychotics.

  2004influential reference
• Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease.

  2003cited by this paper
• Effect of serotonin 1A agonist tandospirone on depression symptoms in senile patients with dementia

  2002cited by this paper
• Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment.

  2001cited by this paper
• Buspirone vs. Haloperidol: A Double-Blind Trial for Agitation in a Nursing Home Population With Alzheimer's Disease.

  1996cited by this paper
• The Neuropsychiatric Inventory

  1994cited by this paper

• Deciphering the Functions of Raphe–Hippocampal Serotonergic and Glutamatergic Circuits and Their Deficits in Alzheimer’s Disease

  2025cites this paper
• Dysregulated Neurotransmitters and CB1 Receptor Dysfunction and Their Roles in Agitation Associated with Alzheimer’s Disease

  2025cites this paper
• Production, Mechanisms, and Therapeutic Strategies of Tryptophan Metabolites in CNS Diseases

  2025influential citation
• Targeting the serotonergic system in the treatment of neurodegenerative diseases—emerging therapies and unmet challenges

  2025cites this paper
• Amygdala neuronal dyshomeostasis via 5‐HT receptors mediates mood and cognitive defects in Alzheimer's disease

  2024cites this paper
• The role of serotonin within the microbiota-gut-brain axis in the development of Alzheimer's disease: a narrative review.

  2022cites this paper
• Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D2 and Serotonin 1A and 2A Receptors in C. elegans

  2022cites this paper
• Medicinal Cannabis and Central Nervous System Disorders

  2022cites this paper
• 5-HT1A Partial Agonist Tandospirone for Behavioral and Psychological Symptoms in Oldest-old Patients with Dementia at a Special Elderly Nursing Home

  2021influential citation
• Tranquilizer/Anxiolytics: Tandospirone

  2021cites this paper
• Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease.

  2021cites this paper
• EEG power spectral analysis reveals tandospirone improves anxiety symptoms in patients with Alzheimer’s disease: a prospective cohort study

  2020influential citation
• Combined network pharmacology and virtual reverse pharmacology approaches for identification of potential targets to treat vascular dementia

  2020cites this paper
• Management of Dementia-Related Psychosis, Agitation and Aggression: A Review of the Pharmacology and Clinical Effects of Potential Drug Candidates

  2020cites this paper
• The Hyperactivity–Impulsivity–Irritiability–Disinhibition–Aggression–Agitation Domain in Alzheimer’s Disease: Current Management and Future Directions

  2019cites this paper
• Serotonergic system, cognition, and BPSD in Alzheimer's disease.

  2019cites this paper
• Methylphenidate-Induced Raynaud Phenomenon Developed After Increasing Methylphenidate in an Adult With Attention-Deficit Hyperactivity Disorder.

  2019cites this paper
• Dose-Dependent Efficacy of Tandospirone for an Oldest-Old Patient With Behavioral and Psychological Symptoms of Dementia.

  2019cites this paper
• Chapter 6 Association of 5-HT 1 A Receptors with Affective Disorders

  2018cites this paper
• Association of 5-HT1A Receptors with Affective Disorders

  2017cites this paper
• Role of tandospirone, a 5-HT1A receptor partial agonist, in the treatment of central nervous system disorders and the underlying mechanisms

  2017cites this paper
• Monoaminergic neuropathology in Alzheimer's disease

  2017influential citation
• Hippocampal 5-HT1A receptor expression changes in prodromal stages of Alzheimer's disease: Beneficial or deleterious?

  2017cites this paper
• Agonist and antagonist bind differently to 5-HT1A receptors during Alzheimer's disease: A post-mortem study with PET radiopharmaceuticals.

  2016cites this paper
• Differential effects of amyloid-beta 1-40 and 1-42 fibrils on 5-HT1A serotonin receptors in rat brain.

  2016cites this paper
• Effect of selective serotonin reuptake inhibitors on expression of 5-HT1AR and neurotransmitters in rats with vascular dementia.

  2016cites this paper
• Chronic treatment with tandospirone, a serotonin 1A receptor partial agonist, inhibits psychosocial stress-induced changes in hippocampal neurogenesis and behavior.

  2015cites this paper
• A Review of Pharmacological Treatments for Depression in Alzheimer's Disease.

  2015cites this paper
• Multitarget‐Directed Tricyclic Pyridazinones as G Protein‐Coupled Receptor Ligands and Cholinesterase Inhibitors

  2015cites this paper
• A Postmortem Study to Compare Agonist and Antagonist 5‐HT1A Receptor‐binding Sites in Alzheimer's Disease

  2014cites this paper
• Kampo therapy and behavioral and psychological symptoms of dementia

  2014cites this paper
• Chronic Treatment with the 5-HT1A Receptor Partial Agonist Tandospirone Increases Hippocampal Neurogenesis

  2014cites this paper
• Serotonergic Therapies for Cognitive Symptoms in Alzheimer’s Disease: Rationale and Current Status

  2014cites this paper
• Yokukan-san: a review of the evidence for use of this Kampo herbal formula in dementia and psychiatric conditions

  2014cites this paper
• Apports de la TEP dans l’imagerie moléculaire des récepteurs sérotoninergiques 5-HT1A et 5-HT7

  2011cites this paper
• Behavioural genetics of Alzheimer's disease: a comprehensive review

  2011cites this paper
• Effects of yokukansan on anxiety-like behavior in a rat model of cerebrovascular dementia

  2011cites this paper
• Effects of amyloid-β peptides on the serotoninergic 5-HT1A receptors in the rat hippocampus.

  2011cites this paper
• Cognitive domains affected by histamine H(1)-antagonism in humans: a literature review.

  2010cites this paper
• Use of Yi-Gan San (TJ-54) in patients with motor aphasia who refuse to participate in rehabilitation

  2010cites this paper
• Successful treatment of extrapyramidal and psychotic symptoms with zonisamide in a patient with dementia with Lewy bodies.

  2010cites this paper
• Synthesis and pharmacological evaluation of aminopyrimidine series of 5-HT1A partial agonists.

  2009cites this paper
• A randomized cross-over study of a traditional Japanese medicine (kampo), yokukansan, in the treatment of the behavioural and psychological symptoms of dementia.

  2009cites this paper
• Vers l'imagerie TEP de la neurotransmission sérotoninergique dans la maladie d'Alzheimer : du radiotraceur au modèle animal.

  2008cites this paper
• Molecular imaging of the 5-HT(1A) receptor in relation to human cognition.

  2008cites this paper
• Alternatives to Atypical Antipsychotics for the Management of Dementia-Related Agitation

  2008cites this paper
• Practical clinical use of therapeutic agents for Alzheimer's disease.

  2007cites this paper