Antidiabetic potential of oleanolic acid from Ligustrum lucidum Ait.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Canadian Journal of Physiology and Pharmacology

• Publication date

  2007-11-19

• Fields of study

  Medicine

• Identifiers
  DOI 10.1139/Y07-098PMID 18066109
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Study of the extraction, purification and antidiabetic potential of ursolic acid from Cornus officinalis Sieb. et Zucc.

  2008cited by this paper
• Botanicals as epigenetic modulators for mechanisms contributing to development of metabolic syndrome.

  2008cited by this paper
• A Case of Hyperglycemic Hyperosmolar State Associated with Graves' Hyperthyroidism: A Case Report

  2006cited by this paper
• Plasma sitosterol elevations are associated with an increased incidence of coronary events in men: results of a nested case-control analysis of the Prospective Cardiovascular Münster (PROCAM) study.

  2006cited by this paper
• Effect of melatonin on the thymus, adrenal glands, and spleen in rats during acute stress

  2006cited by this paper
• Oleanolic acid, a pentacyclic triterpene attenuates capsaicin-induced nociception in mice: possible mechanisms.

  2006cited by this paper
• A Randomized Trial of a Strategy for Increasing High-Density Lipoprotein Cholesterol Levels: Effects on Progression of Coronary Heart Disease and Clinical Events

  2005cited by this paper
• Molecular defects in cardiac myofibrillar proteins due to thyroid hormone imbalance and diabetes.

  2005cited by this paper
• Hypoglycaemic activity of Gentiana olivieri and isolation of the active constituent through bioassay-directed fractionation techniques.

  2005cited by this paper
• Protective effect of Eugenia jambolana seed kernel on tissue antioxidants in streptozotocin-induced diabetic rats.

  2004cited by this paper
• Effects of Ligustrazin on the synthesis of immunoglobulins in peripheral blood mononuclear cells of patients with rheumatoid arthritis

  2004cited by this paper
• Comparising the effects of different preparations of Fructus Ligustri Lucidi on enhancing white blood cell and anti-hypoxia ability

  2004cited by this paper
• Hypoglycaemic and hypolipidemic effect of ethanolic extract of seeds of Eugenia jambolana in alloxan-induced diabetic rabbits.

  2003cited by this paper
• Modulatory Effect of Scoparia dulcis in Oxidative Stress-Induced Lipid Peroxidation in Streptozotocin Diabetic Rats

  2003cited by this paper
• Diabetic dyslipidemia.

  2002cited by this paper
• Thyroid hormone excess and glucose intolerance.

  2001cited by this paper
• Low High-Density Lipoprotein Cholesterol as a Risk Factor in Coronary Heart Disease: A Working Group Report

  2001cited by this paper
• Hypoglycemic effect of Cecropia obtusifolia on streptozotocin diabetic rats.

  2001cited by this paper
• Hypoglycemic effect of Suaeda fruticosa in streptozotocin-induced diabetic rats.

  2001cited by this paper
• From Obesity to Diabetes: Why, When and Who?

  2000cited by this paper
• Obesity, insulin resistance and diabetes — a worldwide epidemic

  2000cited by this paper
• The HISS story overview: a novel hepatic neurohumoral regulation of peripheral insulin sensitivity in health and diabetes.

  1999cited by this paper
• Diabetic ketoacidosis precipitated by thyrotoxicosis

  1999cited by this paper
• Distribution of lipids in 8,500 men with coronary artery disease. Department of Veterans Affairs HDL Intervention Trial Study Group.

  1995cited by this paper
• HDL cholesterol predicts coronary heart disease mortality in older persons.

  1995cited by this paper
• Familial Lipoprotein Disorders in Patients With Premature Coronary Artery Disease

  1992cited by this paper
• Lipolytic and ketogenic fluxes in human hyperthyroidism.

  1991cited by this paper
• Increased Insulin Action and Clearance in Hyperthyroid Newly Diagnosed IDDM Patient: Restoration to Normal With Antithyroid Treatment

  1989cited by this paper
• Fasting and postabsorptive hepatic glucose and insulin metabolism in hyperthyroidism.

  1989cited by this paper
• Skeletal muscle and whole body protein turnover in thyroid disease

  1988cited by this paper
• Insulin Sensitivity and Exogenous Insulin Clearance in Graves' Disease: Measurement by the Glucose Clamp Technique and Continuous Indirect Calorimetry

  1986cited by this paper
• Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen

  1969cited by this paper
• Studies of the Diabetogenic Action of Streptozotocin.∗

  1967cited by this paper

• Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

  2025cites this paper
• Ligustrum L. (Oleaceae) in South Africa: Introduction history and invasion ecology

  2025cites this paper
• Triterpenoid From Persimmon Leaves (Diospyros kaki L.f.) Exerted Anti–Type 2 Diabetic Effects and No Toxicity in Experimental Animals

  2025cites this paper
• Oleanolic acid alleviates obesity‐induced skeletal muscle atrophy via the PI3K/Akt signaling pathway

  2024cites this paper
• Therapeutic effects of Huangqi formula (Eefooton) in chronic kidney disease: clinical research and narrative literature review

  2024cites this paper
• The Effect and Mechanism of Oleanolic Acid in the Treatment of Metabolic Syndrome and Related Cardiovascular Diseases

  2024cites this paper
• Synthesis, Cytotoxicity and Molecular Docking of New Hybrid Compounds by Combination of Curcumin with Oleanolic Acid

  2023cites this paper
• Processing-structure–property relationships of oleanolic acid loaded PLGA fiber membranes

  2023cites this paper
• Pentacyclic triterpene oleanolic acid protects against cardiac aging through regulation of mitophagy and mitochondrial integrity.

  2022cites this paper
• Antidiabetic Potential of Commonly Available Fruit Plants in Bangladesh: Updates on Prospective Phytochemicals and Their Reported MoAs

  2022cites this paper
• Preliminary results on the separation of the different parts of Ligustrum lucidum Ait fruit and the main bioactive compounds analysis

  2022cites this paper
• Hypoglycemic natural products with in vivo activities and their mechanisms: a review

  2022cites this paper
• Ethnopharmacological, Phytochemical, Pharmacological, and Toxicological Review on Senna auriculata (L.) Roxb.: A Special Insight to Antidiabetic Property

  2021cites this paper
• Endoplasmic Reticulum Stress in Diabetic Nephrology: Regulation, Pathological Role, and Therapeutic Potential

  2021cites this paper
• Betulinic acid reduces the complications of autoimmune diabetes on the body and kidney through effecting on inflammatory cytokines in C57BL/6 mice

  2021cites this paper
• Self-assembled micellar nanostructures of ursolic acid-polyethylene glycol (UA-PEG) conjugate as efficient drug transporter system

  2021cites this paper
• Transcriptome study of oleanolic acid in the inhibition of breast tumor growth based on high-throughput sequencing

  2021cites this paper
• Determination of Ursolic Acid in Extracts From Ligustri lucidum Fruit Using an Electrochemical Method

  2020cites this paper
• Chemical composition and glucose uptake effect on 3T3-L1 adipocytes of Ligustrum lucidum Ait. flowers

  2020cites this paper
• Oleanolic acid : Biological activities and therapeutic potential in chronic diseases

  2019cites this paper
• Pharmacological Property of Pentacyclic Triterpenoids

  2019cites this paper
• Screening of Biological Activities of Ligustrum lucidum Berries: A Comparative Approach

  2018cites this paper
• Anti-corrosion and Anti-bacteria Property of Modified Pomegranate Peel Extract

  2018cites this paper
• Anti-diabetic effect of betulinic acid on streptozotocin-nicotinamide induced diabetic male mouse model

  2018cites this paper
• The protective effect of neonatal oral administration of oleanolic acid against the subsequent development of fructose-induced metabolic dysfunction in male and female rats

  2018cites this paper
• Pharmacognostic Studies and HPLC Analysis of Roots of Helicteres isora (L.)

  2017cites this paper
• Host-guest interaction of β-cyclodextrin with isomeric ursolic acid and oleanolic acid: physicochemical characterization and molecular modeling study

  2017cites this paper
• Synthesis of Barringtogenol C Derivatives and Their Cytotoxic Activities

  2017cites this paper
• Investigation of Ligustrum lucidum Ait. Seeds Extract as Green Corrosion Inhibitors and Bacteriostatic Agent

  2016cites this paper
• Glucose consumption and alpha-glucosidase inhibitory activities of aqueous root extract of Helicteres angustifolia.

  2016cites this paper
• Effects of oleanolic acid and Centella asiatica on enzymes of carbohydrate metabolism in muscle and skin of streptozotocin-induced diabetic Sprague-Dawley rats.

  2016cites this paper
• Oleanolic, Ursolic, and Betulinic Acids as Food Supplements or Pharmaceutical Agents for Type 2 Diabetes: Promise or Illusion?

  2016cites this paper
• Oleanolic acid and N-acetylcysteine ameliorate diabetic nephropathy through reduction of oxidative stress and endoplasmic reticulum stress in a type 2 diabetic rat model.

  2016cites this paper
• Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1α/VEGF Signaling Pathway

  2016cites this paper
• Antidiabetic activity of Helicteres angustifolia root

  2016cites this paper
• Studies on the Osteoprotective and Antidiabetic Activities of Moringa Oleifera Plant Extract.

  2015cites this paper
• Quality assessment of Fructus Ligustri Lucidi by the simultaneous determination of six compounds and chemometric analysis.

  2015cites this paper
• Research progress on lipidemic regulation and antiobesity effects of oleanolic acid and ursolic acid

  2015cites this paper
• Development and evaluation of optimized sucrose ester stabilized oleanolic acid nanosuspensions prepared by wet ball milling with design of experiments.

  2014cites this paper
• Synthesis and Evaluation of Novel Oleanolic Acid Derivatives as Potential Antidiabetic Agents

  2014cites this paper
• The pentacyclic triterpenoids in herbal medicines and their pharmacological activities in diabetes and diabetic complications.

  2013cites this paper
• Oleanolic acid prevents progression of streptozotocin induced diabetic nephropathy and protects renal microstructures in Sprague Dawley rats

  2013influential citation
• Oleanolic acid improves hepatic insulin resistance via antioxidant, hypolipidemic and anti-inflammatory effects.

  2013cites this paper
• Integrated LC/MS and GC/MS Metabolomics Data for the Evaluation of Protection Function of FructusLigustriLucidi on Mouse Liver

  2013cites this paper
• Protective effect of oleanolic acid against beta cell dysfunction and mitochondrial apoptosis: crucial role of ERK-NRF2 signaling pathway.

  2013cites this paper
• Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-1c-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis

  2013cites this paper
• Lipid-Regulating Effect of Traditional Chinese Medicine: Mechanisms of Actions

  2012cites this paper
• FATTY ACIDS, PHENOLS CONTENT, AND ANTIOXIDANT ACTIVITY IN Ibervillea sonorae CALLUS CULTURES CONTENIDO DE ACIDOS GRASOS, FENOLES, Y ACTIVIDAD ANTIOXIDANTE EN CULTIVOS DE CALLO DE Ibervillea sonorae

  2012cites this paper
• Ultrasound-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum

  2012cites this paper
• Curative Effects of Oleanolic Acid on Formed Hypertrophic Scars in the Rabbit Ear Model

  2012cites this paper
• Antidiabetic Effects of Corni Fructus Extract in Streptozotocin-Induced Diabetic Rats

  2012cites this paper
• Plant-Derived Agents with Anti-Glycation Activity

  2012cites this paper
• Antidiabetic and antioxidative potentials of Rhodiola sachalinensis polysaccharide

  2012influential citation
• TNF-α inhibitors with anti-oxidative stress activity from natural products.

  2012cites this paper
• Ultrasound-assisted extraction of oleanolic acid and ursolic acid from Ligustrum lucidum Ait.

  2012cites this paper
• FATTY ACIDS, PHENOLS CONTENT, AND ANTIOXIDANT ACTIVITY IN Ibervillea sonorae CALLUS CULTURES

  2012cites this paper
• Antidiabetic effect of Symplocos cochinchinensis (Lour.) S. Moore. in type 2 diabetic rats.

  2011cites this paper
• Microwave-Assisted Extraction of Oleanolic Acid and Ursolic Acid from Ligustrum lucidum Ait

  2011cites this paper
• Relationship between antioxidant and antiglycation ability of saponins, polyphenols, and polysaccharides in Chinese herbal medicines used to treat diabetes

  2011cites this paper
• Development and Validation of an HPTLC Method for the Analysis of Oleanolic Acid from the Roots of Helicteres isora Linn.

  2011cites this paper
• Seasonal variations in metabolite profiling of the fruits of Ligustrum lucidum Ait.

  2011cites this paper
• Evaluation of the potential hypoglycemic and Beta-cell protective constituents isolated from Corni fructus to tackle insulin-dependent diabetes mellitus.

  2011cites this paper
• Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases.

  2011cites this paper
• Formulation, Biological and Pharmacokinetic Studies of Sucrose Ester-Stabilized Nanosuspensions of Oleanolic Acid

  2011cites this paper
• Effects of NaCl and pH on 2-hydroxypropyl-beta-cyclodextrin inclusion with oleanolic acid

  2011cites this paper
• Synergistic antihyperglycemic effects between plant-derived oleanolic acid and insulin in streptozotocin-induced diabetic rats

  2010cites this paper
• Hypoglycemic effects and mechanisms of Portulaca oleracea L. in alloxan-induced diabetic rats

  2010cites this paper
• Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice.

  2010cites this paper
• Anti-diabetic agents from natural products--an update from 2004 to 2009.

  2010cites this paper
• Antidiabetic potential of Lantana aculeata root extract in alloxan-induced diabetic rats

  2010cites this paper
• Chinese herbal medicine for the treatment of people with impaired glucose tolerance and insulin resistance

  2010cites this paper
• Antidiabetic and antioxidant effects of oleanolic acid from Ligustrum lucidum Ait in alloxan‐induced diabetic rats

  2009cites this paper
• Oleanolic Acid, a Plant Triterpenoid, Significantly Improves Survival and Function of Islet Allograft

  2009cites this paper
• Hypoglycemic activity of constituents from Astianthus viminalis in normal and streptozotocin-induced diabetic mice

  2009cites this paper
• A novel AMPK activator from Chinese herb medicine and ischemia phosphorylate the cardiac transcription factor FOXO3.

  2009cites this paper
• Antidiabetic potential of Rhodiola sachalinensis root extract in streptozotocin-induced diabetic rats.

  2009cites this paper
• Study of the extraction, purification and antidiabetic potential of ursolic acid from Cornus officinalis Sieb. et Zucc.

  2008cites this paper
• Botanicals as epigenetic modulators for mechanisms contributing to development of metabolic syndrome.

  2008cites this paper