Serotonin 2A receptors in obsessive-compulsive disorder: a positron emission tomography study with [11C]MDL 100907.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Biological Psychiatry

• Publication date

  2011-11-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/j.biopsych.2011.06.023PMID 21855857PMCID PMC3951757
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Extended characterisation of the serotonin 2A (5-HT2A) receptor-selective PET radiotracer 11C-MDL100907 in humans: Quantitative analysis, test-retest reproducibility, and vulnerability to endogenous 5-HT tone

  2012cited by this paper
• Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder

  2011cited by this paper
• Pediatric obsessive-compulsive disorder, a neurodevelopmental disorder? Evidence from neuroimaging

  2011cited by this paper
• Encyclopedia of Psychopharmacology

  2010cited by this paper
• Reduced serotonin transporter binding in the insular cortex in patients with obsessive-compulsive disorder: A [11C]DASB PET study

  2010cited by this paper
• Using individual items to clarify OCD symptom structure: the case for five factors.

  2009cited by this paper
• Textbook of Anxiety Disorders

  2009cited by this paper
• Brain imaging in pediatric obsessive-compulsive disorder.

  2008cited by this paper
• In vivo PET study of 5HT2A serotonin and D2 dopamine dysfunction in drug-naive obsessive-compulsive disorder

  2008cited by this paper
• Further development of YBOCS dimensions in the OCD Collaborative Genetics study: symptoms vs. categories.

  2008cited by this paper
• Dose–Occupancy Study of Striatal and Extrastriatal Dopamine D2 Receptors by Aripiprazole in Schizophrenia with PET and [18F]Fallypride

  2008cited by this paper
• Validation of a Tracer Kinetic Model for the Quantification of 5-HT2A Receptors in Human Brain with [11C]MDL 100,907

  2007cited by this paper
• Taboo thoughts and doubt/checking: a refinement of the factor structure for obsessive-compulsive disorder symptoms.

  2007cited by this paper
• Association studies of serotonin system candidate genes in early-onset obsessive-compulsive disorder.

  2007cited by this paper
• Consensus Nomenclature for in vivo Imaging of Reversibly Binding Radioligands

  2007cited by this paper
• Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder.

  2006cited by this paper
• Increased 5-HT(2A) receptor binding in euthymic, medication-free patients recovered from depression: a positron emission study with [(11)C]MDL 100,907.

  2006cited by this paper
• Mechanisms of action of current and potential pharmacotherapies of obsessive-compulsive disorder.

  2006cited by this paper
• Patients with obsessive-compulsive disorder have increased 5-HT2A receptor binding in the caudate nuclei.

  2005cited by this paper
• Effects of reduced endogenous 5‐HT on the in vivo binding of the serotonin transporter radioligand 11C‐DASB in healthy humans

  2005cited by this paper
• Serotonin transporters in obsessive-compulsive disorder: a positron emission tomography study with [(11)C]McN 5652.

  2003cited by this paper
• Dysfunctional attitudes and 5-HT2 receptors during depression and self-harm.

  2003cited by this paper
• Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography.

  2003cited by this paper
• Prefrontal Dopamine D1 Receptors and Working Memory in Schizophrenia

  2002cited by this paper
• Brain-behavior relationships in obsessive-compulsive disorder.

  2001cited by this paper
• Brain anatomy and chemistry may predict treatment response in paediatric obsessive--compulsive disorder.

  2001cited by this paper
• Regional cerebral blood flow abnormalities in early-onset obsessive-compulsive disorder: an exploratory SPECT study.

  2001cited by this paper
• Cognitive dysfunction in obsessive‐compulsive disorder

  2000cited by this paper
• Brief screening for family psychiatric history: the family history screen.

  2000cited by this paper
• Segregation of serotonin 5‐HT2A and 5‐HT3 receptors in inhibitory circuits of the primate cerebral cortex

  2000cited by this paper
• Autoradiographic localization of 5‐HT2A receptors in the human brain using [3H]M100907 and [11C]M100907

  2000cited by this paper
• Measurement of Striatal and Extrastriatal Dopamine D1 Receptor Binding Potential With [11C]NNC 112 in Humans: Validation and Reproducibility

  2000cited by this paper
• On the role of cortical glutamate inobsessive‐compulsive disorder and attention‐deficit hyperactivity disorder, two phenomenologically antithetical conditions

  2000cited by this paper
• Characterization of radioactive metabolites of 5-HT2A receptor PET ligand [18F]altanserin in human and rodent.

  1999cited by this paper
• Multimodal image coregistration and partitioning--a unified framework.

  1997cited by this paper
• Serotonin 5‐HT2A receptors are expressed on pyramidal cells and interneurons in the rat cortex

  1997cited by this paper
• Automated three-dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures.

  1997cited by this paper
• [11C]MDL 100907, a radioligland for selective imaging of 5-HT(2A) receptors with positron emission tomography.

  1996cited by this paper
• Controlling the false discovery rate: a practical and powerful approach to multiple testing

  1995cited by this paper
• SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil: kinetic and equilibrium paradigms.

  1994cited by this paper
• The Yale-Brown Obsessive-Compulsive Scale: measures of internal consistency.

  1994cited by this paper
• The serotonin hypothesis of obsessive compulsive disorder: implications of pharmacologic challenge studies.

  1992cited by this paper
• The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability.

  1989cited by this paper
• The Yale-Brown Obsessive Compulsive Scale. II. Validity.

  1989cited by this paper
• Pathogenesis of obsessive-compulsive disorder.

  1989cited by this paper
• Pathogenesis of obsessive-compulsive disorder.

  1989cited by this paper
• The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability

  1989cited by this paper
• A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

  1984cited by this paper
• A RATING SCALE FOR DEPRESSION

  1960cited by this paper

• Increased Neuroplasticity in Frontal Cortex to Reduce Compulsive Behavior: A Preclinical tDCS Study in Male Rats

  2025cites this paper
• Astrocyte Dysfunctions in Obsessive Compulsive Disorder: Rethinking Neurobiology and Therapeutic Targets

  2025cites this paper
• [18F]R91150: Improved radiosynthesis and in vivo evaluation as imaging probe for 5-HT2A receptors.

  2025cites this paper
• Serotonergic underpinnings of obsessive‐compulsive disorder: A systematic review and meta‐analysis of neuroimaging findings

  2024cites this paper
• Obsessive‐compulsive disorder: Etiology, neuropathology, and cognitive dysfunction

  2023cites this paper
• Progress in the application of molecular imaging in psychiatric disorders

  2023cites this paper
• Radiotracers for the Central Serotoninergic System

  2022cites this paper
• Neurobiological outcomes of cognitive behavioral therapy for obsessive-compulsive disorder: A systematic review

  2022cites this paper
• Differential Neurobiological Markers in Phenotype-stratified Rats Modeling High or Low Vulnerability to Compulsive Behavior: A Narrative Review

  2022cites this paper
• Blockade of 5-Hydroxytryptamine 2A Receptor Attenuates Precipitation of Naloxone-Induced Withdrawal Symptoms in Opioid-Exposed Mice

  2022cites this paper
• Pharmacotherapeutic Strategies and New Targets in OCD.

  2021cites this paper
• Harmonizing the Neurobiology and Treatment of Obsessive-Compulsive Disorder.

  2021cites this paper
• “Vicarious exposure”: “Spooky action” at a distance in obsessive-compulsive disorder

  2021cites this paper
• Magnetic Resonance Spectroscopy (MRS) and Positron Emission Tomography (PET) Imaging in Obsessive-Compulsive Disorder.

  2021cites this paper
• Psychiatric Comorbidities and the Risk of Suicide in Obsessive-Compulsive and Body Dysmorphic Disorder

  2020cites this paper
• Apotential role for psilocybin in the treatment of obsessive-compulsive disorder

  2020cites this paper
• The serotonergic system in obsessive-compulsive disorder

  2020cites this paper
• Neuroimaging of Obsessive-Compulsive Disorder: Insights into Serotonergic Mechanisms

  2020cites this paper
• A potential role for psilocybin in the treatment of obsessive-compulsive disorder

  2020cites this paper
• Distribution of 5-HT receptors in the central nervous system: an update

  2020cites this paper
• Obsessive-Compulsive Disorder: Puzzles and Prospects

  2019cites this paper
• Task-based fMRI predicts response and remission to exposure therapy in obsessive-compulsive disorder

  2019cites this paper
• Évaluation de la flexibilité cognitive dans le trouble obsessionnel compulsif : étude de la validité de deux auto-questionnaires comparés à une tâche expérimentale

  2019cites this paper
• Reduced cortical serotonin 5‐HT2A receptor binding and glutamate activity in high compulsive drinker rats

  2018cites this paper
• Imaging and Genetic Approaches to Inform Biomarkers for Anxiety Disorders, Obsessive-Compulsive Disorders, and PSTD.

  2018cites this paper
• Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline

  2018cites this paper
• 5-HT2A Receptors in the Basal Ganglia

  2018cites this paper
• Raphe nuclei echogenicity changes in obsessive-compulsive disorder

  2018cites this paper
• Biological Models and Treatments for OCD in Adults

  2017cites this paper
• A review of the role of serotonin system genes in obsessive‐compulsive disorder

  2017influential citation
• New Trends and Current Status of Positron-Emission Tomography and Single-Photon-Emission Computerized Tomography Radioligands for Neuronal Serotonin Receptors and Serotonin Transporter.

  2017cites this paper
• Cane Toad Skin Extract—Induced Upregulation and Increased Interaction of Serotonin 2A and D2 Receptors via Gq/11 Signaling Pathway in CLU213 Cells

  2017cites this paper
• Tryptophan depletion affects compulsive behaviour in rats: strain dependent effects and associated neuromechanisms

  2017cites this paper
• Biological markers for anxiety disorders, OCD and PTSD – a consensus statement. Part I: Neuroimaging and genetics

  2016cites this paper
• OCD is associated with an altered association between sensorimotor gating and cortical and subcortical 5-HT1b receptor binding.

  2016cites this paper
• The 5-HT2A serotonin receptor in executive function: Implications for neuropsychiatric and neurodegenerative diseases.

  2016cites this paper
• The Role of Serotonin in Orbitofrontal Function and Obsessive-Compulsive Disorder

  2015cites this paper
• OCD: Serotonergic mechanisms

  2014cites this paper
• Activation of serotonin 5-HT2A receptors inhibits high compulsive drinking on schedule-induced polydipsia

  2014cites this paper
• Transcranial sonography in obsessive-compulsive disorder.

  2013cites this paper
• The Impact of a Naturalistic Stressor on Spontaneous Alternation Behavior: A New Animal Model of OCD

  2012cites this paper
• Investigation of Cortical Glutamate–Glutamine and γ-Aminobutyric Acid in Obsessive–Compulsive Disorder by Proton Magnetic Resonance Spectroscopy

  2012cites this paper
• Neuroimaging of serotonin system in anxiety disorders.

  2012cites this paper
• Impaired Sensorimotor Gating in Unmedicated Adults with Obsessive–Compulsive Disorder

  2012cites this paper
• The role of self-construals in obsessive-compulsive disorder

  2012cites this paper
• The serotonergic system in obsessive-compulsive disorder.

  2010cites this paper