Pregnancy impairs ketone body disposal in late gestating ewes: implications for onset of pregnancy toxaemia.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Research in Veterinary Science

• Publication date

  2006-10-01

• Fields of study

  Agricultural and Food Sciences, Medicine, Biology

• Identifiers
  DOI 10.1016/J.RVSC.2005.10.010PMID 16427105
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Spontaneous pregnancy toxaemia (ketosis) in sheep and the role of insulin.

  1998cited by this paper
• [The contributions of the hormones insulin, cortisol, somatotropin and total estrogen to the pathogenesis of sheep ketosis].

  1994cited by this paper
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  1993cited by this paper
• Regulation of fatty acid metabolism and gluconeogenesis by growth hormone and insulin in sheep hepatocyte cultures. Effects of lactation and pregnancy.

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  1991cited by this paper
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  1990cited by this paper
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  1990cited by this paper
• Human ketone body production and utilization studied using tracer techniques: regulation by free fatty acids, insulin, catecholamines, and thyroid hormones.

  1989cited by this paper
• Ketone body production and disposal: effects of fasting, diabetes, and exercise.

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