Contribution of the ATP-Dependent Protease ClpCP to the Autolysis and Virulence of Streptococcus pneumoniae

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Infection and Immunity

• Publication date

  2005-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.73.2.730-740.2005PMID 15664911PMCID PMC546992
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of Heat Shock and Mutations in ClpL and ClpP on Virulence Gene Expression in Streptococcus pneumoniae

  2003cited by this paper
• Contribution of a Response Regulator to the Virulence of Streptococcus pneumoniae Is Strain Dependent

  2003cited by this paper
• Role of Inflammatory Mediators in Resistance and Susceptibility to Pneumococcal Infection

  2002cited by this paper
• Global Transcriptional Analysis of clpP Mutations of Type 2 Streptococcus pneumoniae and Their Effects on Physiology and Virulence

  2002influential reference
• HtrA protease and processing of extracellular proteins of Streptococcus mutans.

  2001cited by this paper
• Complete Genome Sequence of a Virulent Isolate of Streptococcus pneumoniae

  2001cited by this paper
• The Autolytic Enzyme LytA of Streptococcus pneumoniae Is Not Responsible for Releasing Pneumolysin

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Regulation of Streptococcus pneumoniae clp Genes and Their Role in Competence Development and Stress Survival

  2001influential reference
• Genome of the Bacterium Streptococcus pneumoniae Strain R6

  2001cited by this paper
• Pathogenesis of pneumococcal infection.

  2000cited by this paper
• Host Cellular Immune Response to Pneumococcal Lung Infection in Mice

  2000cited by this paper
• Regulation of growth inhibition at high temperature, autolysis, transformation and adherence in Streptococcus pneumoniae by ClpC

  2000influential reference
• The Clp Proteases of Bacillus subtilisAre Directly Involved in Degradation of Misfolded Proteins

  2000cited by this paper
• Regulation by proteolysis: developmental switches.

  1999cited by this paper
• ClpP participates in the degradation of misfolded protein in Lactococcus lactis

  1999cited by this paper
• Emergence of vancomycin tolerance in Streptococcus pneumoniae

  1999cited by this paper
• CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria

  1999cited by this paper
• Posttranslational quality control: folding, refolding, and degrading proteins.

  1999cited by this paper
• A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein.

  1999cited by this paper
• Stress induction of the Bacillus subtilis clpP gene encoding a homologue of the proteolytic component of the Clp protease and the involvement of ClpP and ClpX in stress tolerance

  1998cited by this paper
• Large-scale identification of virulence genes from Streptococcus pneumoniae.

  1998cited by this paper
• Molecular analysis of virulence factors of Streptococcus pneumoniae

  1997cited by this paper
• Molecular analysis of virulence factors of Streptococcus pneumoniae.

  1997cited by this paper
• Competence for genetic transformation in encapsulated strains of Streptococcus pneumoniae: two allelic variants of the peptide pheromone

  1996cited by this paper
• Uptake of Streptococcus pneumoniae by respiratory epithelial cells

  1996cited by this paper
• HSP100/Clp proteins: a common mechanism explains diverse functions.

  1996cited by this paper
• Pathogenesis of pneumococcal infection.

  1995cited by this paper
• Stress induction of clpC in Bacillus subtilis and its involvement in stress tolerance

  1994cited by this paper
• Heat shock proteins: molecular chaperones of protein biogenesis

  1993cited by this paper
• Characterization of a catalase-deficient strain of Neisseria gonorrhoeae: evidence for the significance of catalase in the biology of N. gonorrhoeae

  1993cited by this paper
• Molecular chaperone functions of heat-shock proteins.

  1993cited by this paper
• The Clp proteins: proteolysis regulators or molecular chaperones?

  1992cited by this paper
• Clp P represents a unique family of serine proteases.

  1990cited by this paper
• Biological role of the pneumococcal amidase. Cloning of the lytA gene in Streptococcus pneumoniae.

  1987cited by this paper
• The heat-shock response.

  1986cited by this paper
• The heat shock response.

  1985cited by this paper
• Interaction of the pneumococcal amidase with lipoteichoic acid and choline.

  1985cited by this paper
• Donor deoxyribonucleic acid length and marker effect in pneumococcal transformation

  1979cited by this paper
• A plasmid in Streptococcus pneumoniae

  1979cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• A study of the genetic material determining an enzyme activity in Pneumococcus

  1960cited by this paper
• A study of the genetic material determining an enzyme in Pneumococcus.

  1960cited by this paper
• STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES

  1944cited by this paper

• Beyond nocardioform: Transcriptionally active microbes and host responses in equine mucoid placentitis

  2025cites this paper
• Structure, Function, and Regulation of LytA: The N-Acetylmuramoyl-l-alanine Amidase Driving the “Suicidal Tendencies” of Streptococcus pneumoniae—A Review

  2025cites this paper
• The serine protease HtrA regulates Group B Streptococcus virulence and affects the host response to infection

  2025cites this paper
• MecA: A Multifunctional ClpP‐Dependent and Independent Regulator in Gram‐Positive Bacteria

  2025cites this paper
• Streptococcus lutetiensis and Streptococcus equinus as potential emerging bovine mastitis pathogens

  2024cites this paper
• Streptococcus suis Deploys Multiple ATP‐Dependent Proteases for Heat Stress Adaptation

  2024cites this paper
• Fusarium graminearum Ste3 G-Protein Coupled Receptor: A Mediator of Hyphal Chemotropism and Pathogenesis

  2022cites this paper
• A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance

  2022cites this paper
• Viral community-wide auxiliary metabolic genes differ by lifestyles, habitats, and hosts

  2022cites this paper
• Comprehensive comparative genomics analysis for the emerging human pathogen Streptococcus dysgalactiae subsp. equisimilis (SDSE): A case study and Pan-subspecies genomic analysis

  2021cites this paper
• DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis

  2021cites this paper
• Enyzmes | Clp Proteases

  2021cites this paper
• Protein degradation control and regulation of bacterial survival and pathogenicity: the role of protein degradation systems in bacteria

  2021cites this paper
• Effects of ClpP protease on biofilm formation of Enterococcus faecalis

  2021cites this paper
• Electronic Cigarette (E-Cigarette) Vapor Exposure Alters the Streptococcus pneumoniae Transcriptome in a Nicotine-Dependent Manner without Affecting Pneumococcal Virulence

  2019cites this paper
• Role of ClpX and ClpP in Streptococcus suis serotype 2 stress tolerance and virulence.

  2019cites this paper
• pdh modulate virulence through reducing stress tolerance and biofilm formation of Streptococcus suis serotype 2

  2019cites this paper
• The effects of e-cigarette vapor exposure on the transcriptome and virulence of Streptococcus pneumoniae

  2019cites this paper
• How to become a killer, or is it all accidental? Virulence strategies in oral streptococci

  2018cites this paper
• Transition Metal Homeostasis in Streptococcus pyogenes and Streptococcus pneumoniae.

  2017cites this paper
• The CtsR regulator controls the expression of clpC, clpE and clpP and is required for the virulence of Enterococcus faecalis in an invertebrate model

  2016cites this paper
• Stress Physiology of Lactic Acid Bacteria

  2016cites this paper
• ClpP-deletion impairs the virulence of Legionella pneumophila and the optimal translocation of effector proteins

  2016cites this paper
• ClpP Affects Biofilm Formation of Streptococcus mutans Differently in the Presence of Cariogenic Carbohydrates Through Regulating gtfBC and ftf

  2015cites this paper
• Stress responses in Streptococcus species and their effects on the host

  2015influential citation
• Mechanistic studies of mycobacterial caseinolytic proteases (Clp)

  2014cites this paper
• Stress response and pathogenicity in Streptococcus pneumoniae

  2014influential citation
• Characterization of glycosylation-associated protein, Gap2, required for the biogenesis of Streptococcus parasanguinis fimbriae-associated protein 1, Fap1

  2014influential citation
• Bacterial caseinolytic proteases as novel targets for antibacterial treatment.

  2014cites this paper
• Bacterial proteases and virulence.

  2013cites this paper
• Pneumococcal ClpP modulates the maturation and activation of human dendritic cells: implications for pneumococcal infections

  2013cites this paper
• Streptococcus pneumoniae and reactive oxygen species: an unusual approach to living with radicals.

  2013cites this paper
• Aldehyde Dehydrogenase 1 – A Novel Target of Duocarmycins and Activity Based Protein Profiling during Bacterial Invasion

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• Streptococcus mutans Unique Tandem Repeat Sequence in Is Enhanced by a clpP Transcription of

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• Molecular characterisation of the polyhistidine triad proteins of Streptococcus pneumoniae.

  2013cites this paper
• Looking Deep Inside: Detection of Low-Abundance Proteins in Leaf Extracts of Arabidopsis and Phloem Exudates of Pumpkin1[W]

  2012cites this paper
• Identification and proteome analysis of the two-component VirR/VirS system in epidemic Streptococcus suis serotype 2.

  2012cites this paper
• Development of vaccines and antibody-based therapies against Streptococcus pneumoniae using conserved antigens

  2011cites this paper
• Stress Responses of Streptococci

  2011cites this paper
• Transcriptome analysis reveals that ClpXP proteolysis controls key virulence properties of Streptococcus mutans.

  2011influential citation
• Identification of Genes and Genomic Islands Correlated with High Pathogenicity in Streptococcus suis Using Whole Genome Tilling Microarrays

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• Two Spx proteins modulate stress tolerance , survival , 4 and virulence in Streptococcus mutans 5 6 7

  2010cites this paper
• Screening of In Vivo Activated Genes in Enterococcus faecalis during Insect and Mouse Infections and Growth in Urine

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• The ClpP protease homologue is required for the transmission traits and cell division of the pathogen Legionella pneumophila

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• Two Spx Proteins Modulate Stress Tolerance, Survival, and Virulence in Streptococcus mutans

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• Regulation of CtsR activity in low GC, Gram+ bacteria.

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• ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage.

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• Periodicity of Epidemics of Invasive Disease due to Infection With Streptococcus pneumoniae in the United States

  2010cites this paper
• Role of Clp-mediated proteolysis in the Gram-positive human pathogen Streptococcus pyogenes

  2010cites this paper
• Novel strategies to prevent and treat experimental pneumococcal disease

  2010influential citation
• Gene Regulation in Streptococcus pneumoniae: interplay between nutrition and virulence

  2010influential citation
• Biosynthesis and regulation of cyclic lipopeptides in Pseudomonas fluorescens

  2009cites this paper
• University of Groningen Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence Hendriksen,

  2009cites this paper
• Investigation of the role of a large serine rich repeat protein in Streptococcus pneumoniae

  2009cites this paper
• Contribution of ClpE to virulence of Streptococcus pneumoniae.

  2009cites this paper
• Caseinolytic protease: a protein vaccine which could elicit serotype‐independent protection against invasive pneumococcal infection

  2009cites this paper
• Proteases in bacterial pathogenesis.

  2009cites this paper
• Helicobacter pylori mutants defective in the clpP ATP-dependant protease and the chaperone clpA display reduced macrophage and murine survival.

  2009cites this paper
• Role of Clp Proteins in Expression of Virulence Properties of Streptococcus mutans

  2009cites this paper
• Strain-specific impact of PsaR of Streptococcus pneumoniae on global gene expression and virulence.

  2009cites this paper
• Heat Shock Proteins Are Mediators of Bacterial-Host Interactions

  2009cites this paper
• Ecology of virulence genes in the human pathogen Streptococcus pneumoniae

  2008cites this paper
• β‐Lactone als privilegierte Strukturen für die Markierung des aktiven Zentrums vielfältiger bakterieller Enzymklassen

  2008cites this paper
• Transcription of clpP Is Enhanced by a Unique Tandem Repeat Sequence in Streptococcus mutans

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• Isolation of Streptococcus pneumoniae Biofilm Mutants and Their Characterization during Nasopharyngeal Colonization

  2008cites this paper
• Regulation of Cyclic Lipopeptide Biosynthesis in Pseudomonas fluorescens by the ClpP Protease

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• Pneumolysin: a double-edged sword during the host-pathogen interaction.

  2008cites this paper
• Unique Tandem Repeat Sequence in Is Enhanced by a Clpp Transcription Of

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• Virulence factors in pneumococcal respiratory pathogenesis.

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• Beta-lactones as privileged structures for the active-site labeling of versatile bacterial enzyme classes.

  2008cites this paper
• Differential expression of Streptococcus Pneumoniae genes during pathogenesis.

  2007cites this paper
• Unveiling molecular mechanisms of bacterial surface proteins: Streptococcus pneumoniae as a model organism for structural studies

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• SpxB Is a Suicide Gene of Streptococcus pneumoniae and Confers a Selective Advantage in an In Vivo Competitive Colonization Model

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• Clp ATPases and ClpP proteolytic complexes regulate vital biological processes in low GC, Gram‐positive bacteria

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• Modulation of Adherence, Invasion, and Tumor Necrosis Factor Alpha Secretion during the Early Stages of Infection by Streptococcus pneumoniae ClpL

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• Contribution of Conserved ATP-Dependent Proteases of Campylobacter jejuni to Stress Tolerance and Virulence

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• Phylogenomic analysis of natural selection pressure in Streptococcus genomes

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• Enhanced protection against pneumococcal infection elicited by immunization with the combination of PspA, PspC, and ClpP.

  2007cites this paper
• Proteomic Profiling and Identification of Immunodominant Spore Antigens of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis

  2006cites this paper
• Analysis of the transcriptome of group A Streptococcus in mouse soft tissue infection.

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• Genome Sequence of Avery's Virulent Serotype 2 Strain D39 of Streptococcus pneumoniae and Comparison with That of Unencapsulated Laboratory Strain R6

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• Self‐compartmentalized bacterial proteases and pathogenesis

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• Stress Wars: the Direct Role of Host and Bacterial Molecular Chaperones in Bacterial Infection

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