Expression of atrial natriuretic peptide receptor-A antagonizes the mitogen-activated protein kinases (Erk2 and P38MAPK) in cultured human vascular smooth muscle cells

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Molecular and Cellular Biochemistry

• Publication date

  2002-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1023/A:1015882302796PMID 12083372
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Allosteric regulatory step and configuration of the ATP-binding pocket in atrial natriuretic factor receptor guanylate cyclase transduction mechanism.

  2001cited by this paper
• Natriuretic peptide receptor-A negatively regulates mitogen-activated protein kinase and proliferation of mesangial cells: role of cGMP-dependent protein kinase.

  2000cited by this paper
• Functional domains and expression of truncated atrial natriuretic peptide receptor-A: the carboxyl-terminal regions direct the receptor internalization and sequestration in COS-7 cells.

  2000cited by this paper
• Reciprocal Antagonism Coordinates C-type Natriuretic Peptide and Mitogen-signaling Pathways in Fibroblasts*

  1999cited by this paper
• Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle.

  1999cited by this paper
• Natriuretic peptides.

  1998cited by this paper
• Catalytic activation of the phosphatase MKP-3 by ERK2 mitogen-activated protein kinase.

  1998cited by this paper
• Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase.

  1998cited by this paper
• N ATRIURETIC P EPTIDES

  1998cited by this paper
• Physiology of the natriuretic peptides Gonadal function

  1997cited by this paper
• Expression of guanylyl cyclase-A/atrial natriuretic peptide receptor blocks the activation of protein kinase C in vascular smooth muscle cells. Role of cGMP and cGMP-dependent protein kinase.

  1997cited by this paper
• Mechanisms of natriuretic-peptide-induced growth inhibition of vascular smooth muscle cells.

  1997cited by this paper
• Role of atrial natriuretic factor in volume control.

  1996cited by this paper
• Atrial natriuretic peptide inhibits the phosphoinositide hydrolysis in murine Leydig tumor cells

  1996cited by this paper
• Atrial Natriuretic Peptide Inhibits Mitogen-activated Protein Kinase through the Clearance Receptor

  1996cited by this paper
• Inhibition of Growth Factor-induced Protein Synthesis by a Selective MEK Inhibitor in Aortic Smooth Muscle Cells*

  1996cited by this paper
• Vascular Action Natriuretic Peptide Receptors

  1996cited by this paper
• Atrial Natriuretic Peptide Induces the Expression of MKP-1, a Mitogen-activated Protein Kinase Phosphatase, in Glomerular Mesangial Cells (*)

  1996cited by this paper
• The MAPK signaling cascade

  1995cited by this paper
• Atrial Natriuretic Peptide Suppresses the Transcription of Its Guanylyl Cyclase-linked Receptor (*)

  1995cited by this paper
• The family of guanylyl cyclase receptors and their ligands.

  1994cited by this paper
• Atrial natriuretic factor inhibits the phosphorylation of protein kinase C in plasma membrane preparations of cultured Leydig tumor cells.

  1994cited by this paper
• Atrial natriuretic factor inhibits autophosphorylation of protein kinase C and A 240-kDa protein in plasma membranes of bovine adrenal glomerulose cells: Involvement of cGMP-dependent and independent signal transduction mechanisms

  1994cited by this paper
• Regulation of the expression of cyclic GMP-dependent protein kinase by cell density in vascular smooth muscle cells.

  1994cited by this paper
• Protein kinase C-dependent desensitization of the atrial natriuretic peptide receptor is mediated by dephosphorylation.

  1994cited by this paper
• The mitogen-activated protein kinase signal transduction pathway.

  1993cited by this paper
• A comparison of transoesophageal atrial pacing and direct current cardioversion for the termination of atrial flutter: a prospective, randomised clinical trial.

  1993cited by this paper
• The MAP kinase cascade is essential for diverse signal transduction pathways.

  1993cited by this paper
• Core sequence of ATP regulatory module in receptor guanylate cyclases

  1993cited by this paper
• Neointimal Proliferation: The Role of Basic FGF on Vascular Smooth Muscle Cell Proliferation

  1993cited by this paper
• Smooth muscle cells and the pathogenesis of the lesions of atherosclerosis.

  1993cited by this paper
• MAP kinase and the activation of quiescent cells.

  1993cited by this paper
• Atrial natriuretic peptide inhibits endothelin-1-induced activation of mitogen-activated protein kinase in cultured rat mesangial cells.

  1993cited by this paper
• Stoichiometric analysis of internalization, recycling, and redistribution of photoaffinity-labeled guanylate cyclase/atrial natriuretic factor receptors in cultured murine Leydig tumor cells.

  1993cited by this paper
• Intracellular cyclic GMP receptor proteins

  1993cited by this paper
• Atrial natriuretic factor receptors and signal transduction mechanisms.

  1993cited by this paper
• Phosphorylation of atrial natriuretic factor R1 receptor by serine/threonine protein kinases: evidences for receptor regulation

  1992cited by this paper
• Phenotype related changes of intimal smooth muscle cells from human aorta in primary culture.

  1992cited by this paper
• Guanylyl cyclase receptors and their endocrine, paracrine, and autocrine ligands.

  1992cited by this paper
• Atrial natriuretic factor and related peptide hormones.

  1991cited by this paper
• Atrial natriuretic peptide antagonists: biological evaluation and structural correlations.

  1990cited by this paper
• Regulation of differentiated properties and proliferation of arterial smooth muscle cells.

  1990cited by this paper
• Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells.

  1990cited by this paper
• Diverse biological actions of atrial natriuretic peptide.

  1990cited by this paper
• Molecular cloning and expression of murine guanylate cyclase/atrial natriuretic factor receptor cDNA.

  1990cited by this paper
• Stimulation of protein phosphorylation by atrial natriuretic factor in plasma membranes of bovine adrenal cortical cells.

  1989cited by this paper
• Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells

  1988cited by this paper
• Identification and characterization of three distinct atrial natriuretic factor receptors. Evidence for tissue-specific heterogeneity of receptor subtypes in vascular smooth muscle, kidney tubular epithelium, and Leydig tumor cells by ligand binding, photoaffinity labeling, and tryptic proteolysis.

  1988cited by this paper
• Atrial natriuretic factor: a hormone produced by the heart.

  1985cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper

• Expression and Regulation of Npr1 Gene Coding for Natriuretic Peptide Receptor-A in Hypertrophied Heart: Mechanisms and Therapeutic Implications

  2026cites this paper
• Guanylyl cyclase/natriuretic peptide receptor-A: Identification, molecular characterization, and physiological genomics

  2023influential citation
• Molecular Signaling Mechanisms and Function of Natriuretic Peptide Receptor-A in the Pathophysiology of Cardiovascular Homeostasis

  2021cites this paper
• Angiotensin II represses Npr1 expression and receptor function by recruitment of transcription factors CREB and HSF-4a and activation of HDACs

  2020cites this paper
• Depletion of cyclic‐GMP levels and inhibition of cGMP‐dependent protein kinase activate p21Cip1/p27Kip1 pathways and lead to renal fibrosis and dysfunction

  2020cites this paper
• Genetic disruption of guanylyl cyclase/natriuretic peptide receptor‐A upregulates renal (pro)renin receptor expression in Npr1 null mutant mice

  2019cites this paper
• Molecular and genetic aspects of guanylyl cyclase natriuretic peptide receptor-A in regulation of blood pressure and renal function.

  2018cites this paper
• Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure

  2018cites this paper
• Chinese liquor extract enhances inflammation resistance in RAW 264.7 and reduces aging in Caenorhabditis elegans

  2018cites this paper
• The renal and cardiovascular effects of natriuretic peptides.

  2017influential citation
• Clathrin-dependent internalization, signaling, and metabolic processing of guanylyl cyclase/natriuretic peptide receptor-A

  2017cites this paper
• HISTONES, HISTONE ACETYLTRANSFERASE, p300, AND Sp1 Cyclase/Natriuretic Peptide Receptor-A Gene: INTERACTIVE ROLES OF MODIFIED Histone Deacetylase Inhibitors Modulate the Transcriptional Regulation of Guanylyl

  2015cites this paper
• Atrial natriuretic peptide inhibits cell cycle activity of embryonic cardiac progenitor cells via its NPRA receptor signaling axis.

  2015cites this paper
• Subcellular trafficking of guanylyl cyclase/natriuretic peptide receptor-A with concurrent generation of intracellular cGMP

  2015cites this paper
• Guanylyl cyclase/natriuretic peptide receptor-A signaling antagonizes phosphoinositide hydrolysis, Ca2+ release, and activation of protein kinase C

  2014cites this paper
• Functional O-GlcNAc modifications: Implications in molecular regulation and pathophysiology

  2014cites this paper
• Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.

  2013cites this paper
• Functional silencing of guanylyl cyclase/natriuretic peptide receptor-A by microRNA interference: analysis of receptor endocytosis.

  2013influential citation
• The Effects of Calcium Channel Blockade and Atrial Natriuretic Peptide Signalling on Proliferation and Differentiation of Cardiac Progenitor Cells

  2013cites this paper
• Activation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice.

  2012cites this paper
• Guanylyl cyclase/natriuretic peptide receptor-A signaling antagonizes the vascular endothelial growth factor-stimulated MAPKs and downstream effectors AP-1 and CREB in mouse mesangial cells

  2012cites this paper
• Mechanosensitive Pro-inflammatory Gene Expression in Vascular Cells

  2012cites this paper
• Chapiter 10: Identification of mechanosensitive genes in chondrocytes and osteoblasts and their role in OA pathogenesis

  2012cites this paper
• The toll‐like receptor 4‐antagonist eritoran reduces murine cardiac hypertrophy

  2011cites this paper
• The functional genomics of guanylyl cyclase/natriuretic peptide receptor‐A: Perspectives and paradigms

  2011cites this paper
• Hepatic stellate cells produce vascular endothelial growth factor via phospho-p44/42 mitogen–activated protein kinase/cyclooxygenase-2 pathway

  2011cites this paper
• Guanylyl cyclase / atrial natriuretic peptide receptor-A: role in the pathophysiology of cardiovascular regulation.

  2011cites this paper
• Targeted disruption of guanylyl cyclase-A/natriuretic peptide receptor-A gene provokes renal fibrosis and remodeling in null mutant mice: role of proinflammatory cytokines.

  2010cites this paper
• Atrial natriuretic peptide promotes pancreatic islet beta-cell growth and Akt/Foxo1a/cyclin D2 signaling.

  2009cites this paper
• Natriuretic Peptides and Cardiovascular Regulation

  2009cites this paper
• Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO* and beyond.

  2009cites this paper
• Molecular regulation of cardiac hypertrophy.

  2008cites this paper
• Emerging Roles of Natriuretic Peptides and their Receptors in Pathophysiology of Hypertension and Cardiovascular Regulation.

  2008cites this paper
• Cyclic GMP-specific phosphodiesterase 5 regulates growth and apoptosis in pulmonary endothelial cells.

  2005cites this paper
• Biology of natriuretic peptides and their receptors.

  2005cites this paper
• Involvement of the NF-κB/Matrix Metalloproteinase Pathway in Cardiac Fibrosis of Mice Lacking Guanylyl Cyclase/Natriuretic Peptide Receptor A*

  2005cites this paper
• Local Atrial Natriuretic Peptide Signaling Prevents Hypertensive Cardiac Hypertrophy in Endothelial Nitric-oxide Synthase-deficient Mice*

  2005cites this paper
• Reduced cGMP signaling activates NF-kappaB in hypertrophied hearts of mice lacking natriuretic peptide receptor-A.

  2005cites this paper
• Intraluminal Pressure Is a Stimulus for NFATc3 Nuclear Accumulation

  2004cites this paper
• Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A.

  2003cites this paper
• Functional Interplay Between Angiotensin II and Nitric Oxide: Cyclic GMP as a Key Mediator

  2003cites this paper