Ciliar functions in the nephron

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Pflügers Archiv: European Journal of Physiology

• Publication date

  2009-01-20

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00424-008-0632-0PMID 19153764
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chapter 7 – Autosomal Recessive Polycystic Kidney Disease

  2008cited by this paper
• Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia.

  2008cited by this paper
• Evaluation of Genetic Association and Expression Reduction of TRPC1 in the Development of Diabetic Nephropathy

  2008influential reference
• Slow spontaneous [Ca2+]i oscillations reflect nucleotide release from renal epithelia

  2008cited by this paper
• Structure and function of mammalian cilia

  2008cited by this paper
• Formation of a new receptor‐operated channel by heteromeric assembly of TRPP2 and TRPC1 subunits

  2008influential reference
• Sensory roles of neuronal cilia: cilia development, morphogenesis, and function in C. elegans.

  2008cited by this paper
• Ciliary dysfunction in polycystic kidney disease: an emerging model with polarizing potential.

  2008cited by this paper
• TRPP2 and TRPV4 form a polymodal sensory channel complex

  2008influential reference
• Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1)

  2007cited by this paper
• Polycystic kidney disease and the renal cilium.

  2007cited by this paper
• Discinesia ciliar primária: considerações sobre seis casos da síndrome de Kartagener

  2007cited by this paper
• Differences in Renal Tubule Primary Cilia Length in a Mouse Model of Bardet-Biedl Syndrome

  2007influential reference
• Role of primary cilia in the pathogenesis of polycystic kidney disease.

  2007cited by this paper
• The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells

  2007cited by this paper
• Fibrocystin/Polyductin, Found in the Same Protein Complex with Polycystin-2, Regulates Calcium Responses in Kidney Epithelia

  2007influential reference
• Force-response considerations in ciliary mechanosensation.

  2007cited by this paper
• Transient receptor potential cation channels in disease.

  2007cited by this paper
• Flow-induced [Ca2+]i increase depends on nucleotide release and subsequent purinergic signaling in the intact nephron.

  2007cited by this paper
• Primary ciliary dyskinesia: considerations regarding six cases of Kartagener syndrome.

  2007cited by this paper
• Polycystic kidney disease and the renal cilium (Review Article)

  2007cited by this paper
• Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals

  2007cited by this paper
• Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein.

  2006cited by this paper
• The versatile nature of the calcium‐permeable cation channel TRPP2

  2006cited by this paper
• Polycystin-2 traffics to cilia independently of polycystin-1 by using an N-terminal RVxP motif

  2006cited by this paper
• Polycystic kidney disease: cell division without a c(l)ue?

  2006cited by this paper
• Primary cilium formation requires von hippel-lindau gene function in renal-derived cells.

  2006cited by this paper
• Nephrocystin specifically localizes to the transition zone of renal and respiratory cilia and photoreceptor connecting cilia.

  2006cited by this paper
• Phenotypic characterization of Bbs4 null mice reveals age-dependent penetrance and variable expressivity

  2006cited by this paper
• A physiological view of the primary cilium.

  2005cited by this paper
• Vertebrate Smoothened functions at the primary cilium

  2005cited by this paper
• Polycystins: polymodal receptor/ion-channel cellular sensors

  2005cited by this paper
• Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease?

  2005influential reference
• Expression of sperm protein 17 (Sp17) in ovarian cancer

  2004cited by this paper
• Beta1-integrins in the primary cilium of MDCK cells potentiate fibronectin-induced Ca2+ signaling.

  2004influential reference
• Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly.

  2004cited by this paper
• Membrane Trafficking of Angiotensin Receptor Type-1 and Mechanochemical Signal Transduction in Proximal Tubule Cells

  2004cited by this paper
• Global cytoskeletal control of mechanotransduction in kidney epithelial cells.

  2004cited by this paper
• The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression

  2004cited by this paper
• Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin.

  2004cited by this paper
• Gating of the polycystin ion channel signaling complex in neurons and kidney cells

  2004cited by this paper
• From cilia to cyst

  2003cited by this paper
• Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

  2003influential reference
• Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination

  2003influential reference
• New insights into ciliary function: Kidney cysts and photoreceptors

  2003cited by this paper
• Autosomal dominant polycystic kidney disease.

  2003cited by this paper
• Polycystic kidney disease--the ciliary connection.

  2003cited by this paper
• Ciliary function of polycystins: a new model for cystogenesis.

  2003cited by this paper
• Removal of the MDCK Cell Primary Cilium Abolishes Flow Sensing

  2003cited by this paper
• The renal cell primary cilium functions as a flow sensor.

  2003cited by this paper
• Autosomal dominant polycystic kidney disease: molecular genetics and pathophysiology.

  2003cited by this paper
• Specific lectins map the distribution of fibronectin and beta 1-integrin on living MDCK cells.

  2002cited by this paper
• The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia.

  2002cited by this paper
• Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease.

  2002cited by this paper
• Effects of luminal flow and nucleotides on [Ca(2+)](i) in rabbit cortical collecting duct.

  2002cited by this paper
• Cilia in PKD--letting it all hang out.

  2002cited by this paper
• Polycystin-2 localizes to kidney cilia and the ciliary level is elevated in orpk mice with polycystic kidney disease.

  2002cited by this paper
• A Proteomic Analysis of Human Cilia

  2002cited by this paper
• Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle.

  2002cited by this paper
• Bending the MDCK Cell Primary Cilium Increases Intracellular Calcium

  2001influential reference
• Epithelial Na(+) channels are regulated by flow.

  2001influential reference
• Extracellular ATP and cAMP as Paracrine and Interorgan Regulators of Renal Function P2Y Receptors of MDCK Cells: Epithelial Cell Regulation by Extracellular Nucleotides

  2001cited by this paper
• Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia.

  2001cited by this paper
• Cell to Cell Communication in Response to Mechanical Stress via Bilateral Release of Atp and Utp in Polarized Epithelia

  2000cited by this paper
• Molecular genetics and mechanism of autosomal dominant polycystic kidney disease.

  2000cited by this paper
• The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination.

  2000cited by this paper
• An ever-expanding story of cyst formation

  2000cited by this paper
• Chlamydomonas IFT88 and Its Mouse Homologue, Polycystic Kidney Disease Gene Tg737, Are Required for Assembly of Cilia and Flagella

  2000cited by this paper
• Localization of 5-HT(6) receptors at the plasma membrane of neuronal cilia in the rat brain.

  2000cited by this paper
• Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

  2000cited by this paper
• Selective targeting of somatostatin receptor 3 to neuronal cilia.

  1999cited by this paper
• A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans

  1999cited by this paper
• Cloning of inv, a gene that controls left/right asymmetry and kidney development

  1998cited by this paper
• Prenatal diagnosis of autosomal recessive polycystic kidney disease (ARPKD): molecular genetics, clinical experience, and fetal morphology.

  1998cited by this paper
• A release mechanism for stored ATP in ocular ciliary epithelial cells.

  1998cited by this paper
• Prenatal Diagnosis of Autosomal Recessive Polycystic Kidney Disease (ARPKD): Molecular Genetics, Clinical Experience, and Fetal Morphology

  1998cited by this paper
• Somatic inactivation of Pkd2 results in polycystic kidney disease.

  1998cited by this paper
• Analysis and modeling of the primary cilium bending response to fluid shear.

  1997cited by this paper
• Release, metabolism and interconversion of adenine and uridine nucleotides: implications for G protein-coupled P2 receptor agonist selectivity.

  1997cited by this paper
• Role of integrins in cellular responses to mechanical stress and adhesion.

  1997cited by this paper
• Mechanisms of integrin-mediated calcium signaling in MDCK cells: regulation of adhesion by IP3- and store-independent calcium influx.

  1996cited by this paper
• Autosomal recessive polycystic kidney disease: clinical features and genetics.

  1996cited by this paper
• Insertional mutagenesis and molecular analysis of a new gene associated with polycystic kidney disease.

  1995influential reference
• A motility in the eukaryotic flagellum unrelated to flagellar beating.

  1993cited by this paper
• Flexible-substratum technique for viewing cells from the side: some in vivo properties of primary (9+0) cilia in cultured kidney epithelia.

  1988cited by this paper
• Juvenile nephronophthisis

  1981cited by this paper
• Localization of calcium channels in Paramecium caudatum.

  1977cited by this paper
• A critical reevaluation of the structure of the rat uriniferous tubule as revealed by scanning electron microscopy

  1976cited by this paper
• CILIA IN DIFFERENT SEGMENTS OF THE RAT NEPHRON

  1961cited by this paper
• Beiträge zur Kenntniss einiger Drüsen und Epithelien

  1898cited by this paper
• Gray's Anatomy

  year unknowncited by this paper

• CFTR and PC2, partners in the primary cilia in ADPKD.

  2023cites this paper
• A comprehensive review on advancements in tissue engineering and microfluidics toward kidney-on-chip.

  2022cites this paper
• Anoctamin 1 Inhibition Suppresses Cystogenesis by Enhancing Ciliogenesis and the Ciliary Dosage of Polycystins.

  2022cites this paper
• Motile Cilia on Kidney Proximal Tubular Epithelial Cells Are Associated With Tubular Injury and Interstitial Fibrosis

  2022cites this paper
• Aldosterone controls primary cilium length and cell size in renal collecting duct principal cells

  2019cites this paper
• Sensing Fluid-Shear Stress in the Endothelial System with a Special Emphasis on the Primary Cilium

  2018cites this paper
• Can Tissue Cilia Lengths and Urine Cilia Proteins Be Markers of Kidney Diseases?

  2018cites this paper
• Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction.

  2016influential citation
• Antennas of organ morphogenesis: the roles of cilia in vertebrate kidney development

  2016cites this paper
• Flow stimulated endocytosis in the proximal tubule

  2015cites this paper
• Investigating nephronophthisis using a novel murine and cell model

  2014cites this paper
• Cyst formation following disruption of intracellular calcium signaling

  2014cites this paper
• Urinary extracellular vesicles and the kidney: biomarkers and beyond.

  2014cites this paper
• Autosomal dominant policystic kidney disease, more than a renal disease.

  2014cites this paper
• Reduction of oxidative stress during recovery accelerates normalization of primary cilia length that is altered after ischemic injury in murine kidneys.

  2013cites this paper
• Shear stress-induced Ca²⁺ mobilization in MDCK cells is ATP dependent, no matter the primary cilium.

  2013cites this paper
• Regenerative medicine for the kidney: stem cell prospects & challenges

  2013cites this paper
• Generation of a Murine Model for Renal Cell Carcinoma by Overexpression of HIF2α

  2013cites this paper
• CD133 and CD24 expression in renal tissue of patients affected by autosomal dominant polcystic kidney disease

  2013cites this paper
• Adult Renal Cystic Disease: Current Update on Pathogenesis, Cross-sectional Imaging Findings and Management

  2013cites this paper
• Zebrafish models of cystic kidney disease related ciliopathies

  2013cites this paper
• Primary cilia as biomechanical sensors in regulating endothelial function.

  2012cites this paper
• Uriniferous tubule: structural and functional organization.

  2012cites this paper
• Adult renal cystic disease: a genetic, biological, and developmental primer.

  2010cites this paper
• Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

  2010cites this paper
• Primary cilia disappear in rat podocytes during glomerular development

  2010cites this paper
• Characterization of polycystic kidney disease in the Lewis Polycystic Kidney rat

  2010cites this paper
• Liver and kidney disease in ciliopathies

  2009cites this paper
• A molecularly guided tour along the nephron

  2009cites this paper
• The dentin–pulp border: a dynamic interface between hard and soft tissues

  2009cites this paper