Modular Assembly of a Pd Catalyst within a DNA Scaffold for the Amplified Colorimetric and Fluorimetric Detection of Nucleic Acids

Catalytic signal amplification is a powerful tool for the detection of chemical and biological analytes. In chemistry it has been employed in sensing various toxic metal ions (e.g. Pd2+, Pb2+, Cu2+, and Hg2+)[1] as well as small molecules such as carbon monoxide[2] and thiols.[3] In a biological context, catalytic reactions have enabled the highly sensitive detection of scarce analytes. They have been widely utilized, for instance, in the detection and assay of proteins,[4] antibodies,[5] and nucleic acids.[6]

• Publication year

  2012

• Venue

  Angewandte Chemie

• Publication date

  2012-10-17

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/anie.201206006PMID 23076826PMCID 3533772
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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