Sufu and Kif7 in limb patterning and development

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Developmental Dynamics

• Publication date

  2015-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/dvdy.24249PMID 25581370
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.

  2015cited by this paper
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  2014cited by this paper
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  2014influential reference
• Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants.

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• Positive and Negative Regulation of Gli Activity by Kif7 in the Zebrafish Embryo

  2013influential reference
• Meteorological Influences on the Incidence of Aneurysmal Subarachnoid Hemorrhage – A Single Center Study of 511 Patients

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• Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis

  2012influential reference
• GLI Proteins in Human Genetic Disease

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• Dual function of suppressor of fused in Hh pathway activation and mouse spinal cord patterning.

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• Suppressor of Fused (Sufu) Mediates the Effect of Parathyroid Hormone-like Hormone (Pthlh) on Chondrocyte Differentiation in the Growth Plate*

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  2011cited by this paper
• Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu

  2011influential reference
• Dual Phosphorylation of Suppressor of Fused (Sufu) by PKA and GSK3β Regulates Its Stability and Localization in the Primary Cilium*

  2011cited by this paper
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  2010cited by this paper
• A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes

  2010cited by this paper
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  2010influential reference
• Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors

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• Patched 1 conditional null allele in mice

  2003influential reference
• Progression of Vertebrate Limb Development Through SHH-Mediated Counteraction of GLI3

  2002cited by this paper
• Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling.

  2002cited by this paper
• Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer

  2002cited by this paper
• Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

  2002cited by this paper
• Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.

  2000influential reference
• Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb.

  2000cited by this paper
• Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development.

  1997cited by this paper
• Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.

  1997cited by this paper
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  1997cited by this paper
• Biological Crystallography Structural Basis of Sufu–gli Interaction in Human Hedgehog Signalling Regulation

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  2020cites this paper
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